Vaccine related seizures

[RobinN]

Good for you... I hope you can convince others that this has occurred. I guess we all need to start videotaping our children for more reasons than just remembering birthdays.

[RobinN]

An evolving series of articles about vaccine-injury and thimerosal litigation in the civil courts, the Vaccine Injury Compensation Program and Omnibus Autism Proceeding, and the attorneys and “experts” who promote speculative, marginally supported hypotheses of disability causation.

http://neurodiversity.com/weblog/article/162

[RobinN]

Wilson: Some Vaccines Still Contain Mercury

It’s the controversy that won’t go away. Is the skyrocketing rate of Autism in children due in any way to the mercury long contained in childhood vaccines? It’s an issue our chief investigative reporter Steve Wilson has stayed with from the start…and Steve will science ever answer this one?

A loving grandmother and president of the American Academy of Pediatrics, Dr. Renee Jenkins is among those in medicine, in government, in the media, pretty much telling parents this problem’s been solved…there is no mercury in the routine schedule of childhood vaccines anymore, except maybe just “trace” amounts. She’s talking about a mercury-based vaccine preservative called Thimerosal…and the truth is there’s still as much as ever in 11 vaccines including most flu vaccines injected into pregnant women and kids, and some of them younger than 9 get two doses in a season. And also high levels of mercury from Thimerosal in tetanus shots and the boosters routinely injected into 11-year-olds…and also in some meningitis and diphtheria-tetanus formulas, too.

http://www.wxyz.com/content/news/inv...e-1241f33b57fd


http://www.vaccinesafety.edu/thi-table.htm

[RobinN]

Nine studies connecting vaccines to neurological problems.
I have added the Bold text

1. Status epilepticus and lymphocytic pneumonitis following
hepatitis B vaccination.

Authors:de Carvalho, Jozélio Freire1,2
Shoenfeld, Yehuda2,3 shoenfel@post.tau.ac.il

Source:European Journal of Internal Medicine; Jul2008, Vol. 19 Issue 5, p383-385, 3p

Document Type:ArticleSubject Terms:*EPILEPTICS
*LYMPHOCYTES
*HEPATITIS B -- Vaccination
*MEDICINE, Preventive

Abstract: The case reported refers to a patient who developed status
epilepticus in the day of her third dose of hepatitis B vaccination
and we review the literature on this subject. A 12 year-old girl,
without a relevant previous history, taking no drugs, developed a
seizure attack followed by unconsciousness, and eventually died after
three days of her third dose of hepatitis B (HB) vaccination. Autopsy
study revealed cerebral edema with congestion and herniation and
diffuse interstitial type pneumonitis. There seem to be a straight
forward time relationship between the third HB vaccine, the event of
convulsion and the sudden death of the patient. We suggest that, in
some cases, vaccination may be the triggering factor for autoimmune
and neurological disturbances in genetically predisposed individuals
and physicians should be aware of this possible association.
[Copyright 2008 Elsevier]

2. Clinical & Experimental Immunology; Nov2005, Vol. 142 Issue 2,
p377-380, 4p

Document Type:
Article
Subject Terms:
*HEPATITIS B -- Vaccination
*HEPATITIS B vaccine
*ANTIPHOSPHOLIPID syndrome
*VACCINATION
*IMMUNOGLOBULINS

Author-Supplied Keywords:
autoimmunity
hepatitis B

NAICS/Industry Codes:
923120 Administration of Public Health Programs
Abstract:
This study was undertaken to evaluate the possible role of hepatitis
B recombinant vaccine inducing the synthesis of IgG and IgM anti-
cardiolipin antibodies (aCL), antibodies against β₂GPI
(anti-β₂GPI), lupus anti-coagulant (LA), anti-nuclear
antibodies and antibodies against extractable nuclear antigens (anti-
ENA). The study population consisted of 85 healthy students (63
female, 22 male; mean age 20•8 years), vaccinated with three doses of
recombinant DNA hepatitis B vaccine. One month after vaccination with
the first dose of hepatitis B vaccine a minority of vaccinated
individuals showed changes in IgG or IgM aCL or anti-β₂GPI
or LA activity ( P < 0•001). Among subjects in whom changes of IgG
anti-β₂GPI were observed, a significantly higher number of
increased (8/85) than decreased (2/85) values were found ( P < 0•01).
Analyses of paired data showed that differences in aCL or anti-
β₂GPI levels before vaccination or 1 month later did not
reach statistical significance. In two people aCL transitorily
reached medium positivity after the first dose of hepatitis B vaccine
with a drop 5 months later. Similar evident anti-β₂GPI
fluctuation was also observed in one person. Another participant was
initially low positive for IgG anti-β2GPI and the levels were
increasing after vaccination. Two participants became positive for
anti-nuclear antibodies during 6 months' follow-up. There were no sex-
dependent differences in tested antibodies observed and no
associations between levels of aPL and levels of anti-HBV antibodies.
We conclude that HBV can induce aPL, although rarely. In genetically
susceptible individuals or together with some other triggers such
combination might confer the risk of developing a continuous
autoimmune response in an individual. [ABSTRACT FROM AUTHOR]

3. Cytokine profile after rubella vaccine inoculation: evidence of
the immunosuppressive effect of vaccination

Alexander L. Pukhalsky,1 Galina V. Shmarina,1 Maria S. Bliacher,2
Irina M. Fedorova,2 Anna P. Toptygina,2 Julia J. Fisenko,2 and
Vladimir A. Alioshkin2
1Research Centre for Medical Genetics, 1 Moskvorechie Stree, Moscow
115478, Russia
2Moscow G.N. Gabrichevsky Institute of Epidemiology and Microbiology,
Moscow, Russia

Abstract

Background: Immunization with live virus vaccines may cause an
immunosuppression with lymphopaenia, impaired cytokine production and
defective lymphocyte response to mitogenes. These abnormalities were
described in subjects vaccinated against measles. This study was
performed to analyse the host immune response related to
immunosuppression in subjects vaccinated with live attenuated rubella
vaccine.

Methods: Eighteen schoolgirls, aged 11-13 years, were vaccinated with
live attenuated rubella vaccine Rudivax®. Before immunization, and 7
and 30 days after, peripheral blood was collected. Cellular fractions
were subjected to flow cytometric analysis, and the lymphocyte
response to phytohaemagglutinin was investigated. Plasma samples were
analysed for cytokines (interleukin (IL)-4, IL-10, tumour necrosis
factor-α, and interferon-γ) by enzyme-linked immunosorbent assay
techniques.

Results: On day 7 after vaccination, the number of each lymphocyte
subset was decreased; however, only for CD3 and CD4 lymphocytes has a
significant reduction been shown. On the contrary, tumour necrosis
factor-α and IL-10 levels markedly increased and amounted to its
maximum on day 30. Simultaneously, a significant reduction in plasma
interferon-γ and a profound decrease of the lymphocyte response to
phytohaemagglutinin were shown. The changes were accompanied with
marked elevation of plasma IL-4.

Conclusions: Our data indicate that the vaccination with live
attenuated rubella vaccine results in moderate but sustained immune
disturbance. The signs of immunosuppression, including defective
lymphocyte response to mitogene and impaired cytokine production, may
persist for at least 1 month after vaccination.

4. Autism May Be Caused By An Immune System Response To A Virus
ScienceDaily (Nov. 3, 199

— ANN ARBOR---Antibodies found in the blood of autistic children
suggest that at least some cases of autism are caused by a misguided
immune response, triggered by exposure to a virus, researchers in the
University of Michigan's College of Pharmacy report.
________________________________________
The researchers found that autistic children who had been exposed to
certain viruses in the past showed unusually high levels of
antibodies to brain proteins, suggesting an autoimmune response.
Their findings appear in the October issue of the peer-reviewed
journal, Clinical Immunology and Immunopathology.
Autism is a developmental disorder that affects brain function,
interfering with reasoning ability, imagination, communication, and
social interaction. Children with autism start talking later than
other children, and when they do speak, their communication skills
are extremely limited. They often avoid looking at other people and
don't learn to read others' faces for signs of emotion or other cues.
These children typically are unable to play creatively, and some
engage in repetitive, sometimes self-destructive, behavior, such as
rocking, hand flapping or head-banging.
No single cause of autism has been found, and researchers believe
that genes and environmental factors (such as viruses or chemicals)
both may contribute. The kinds of brain abnormalities found in people
with autism suggest that the disorder arises when something disrupts
normal brain development.
One possibility is that early exposure to a virus prods the body into
mounting an immune response that somehow goes awry. In addition to
producing antibodies against the virus, the body makes antibodies
against itself, resulting in damage to tissues and organs.
This "autoimmune" response is what happens in autoimmune diseases
such as lupus, and some researchers think a similar response may
account for the brain abnormalities found in people with autism.
It was this possibility that U-M researchers Vijendra Singh and
Victor Yang and undergraduate student assistant Sheren Lin
investigated. In their study of 48 autistic children and 34 normal
children and adults, the researchers measured levels of antibodies to
two viruses---measles virus and human herpesvirus-6---in the
subjects' blood. These antibodies were chosen because they are often
used in research on known autoimmune diseases, says Singh, the
principal investigator of the project and an assistant research
scientist in the College of Pharmacy.
The researchers also measured levels of two brain autoantibodies
(antibodies to brain tissue). One, anti-MBP, is an antibody to myelin
basic protein, a protein found in the protective sheaths around nerve
fibers in the brain. The other, anti-NAFP, is an antibody to neuron-
axon filament protein, a protein that makes up the nerve fibers
themselves.
Virus antibody levels were essentially the same in autistic and non-
autistic subjects, as the researchers expected. But the majority of
autistic children who had virus antibodies also had brain
autoantibodies. The higher the level of virus antibodies, the more
likely an autistic child was to have brain autoantibodies. None of
the non-autistic subjects had brain autoantibodies.
The strongest link found in the autistic children was between measles
virus antibodies and anti-MBP, suggesting that exposure to the
measles virus may trigger an autoimmune response that interferes with
the development of myelin, says Singh. If myelin in the brain doesn't
develop properly, nerve fibers won't work as they should. This could
be one way that the brain abnormalities associated with autism arise.
The question of how exposure to measles virus occurs raises a
controversial issue. Parents of children with autism often report
that the children started showing signs of the disorder shortly after
being immunized with measles-mumps-rubella (MMR) or diphtheria-
pertussis-tetanus (DPT) vaccine, but no scientific studies have shown
a link between vaccines and autism. In the U-M study, almost all the
subjects had had MMR immunizations, and none had ever had a case of
measles. It is possible, however, that some might have been infected
with measles virus but never developed symptoms of measles, says
Singh.
________________________________________
Adapted from materials provided by University Of Michigan.
Need to cite this story in your essay, paper, or report? Use one of
the following formats:
APA

[RobinN]

continued:

MLA
University Of Michigan (1998, November 3). Autism May Be Caused By An
Immune System Response To A Virus. ScienceDaily. Retrieved May 26,
2008, from
http://www.sciencedaily.com¬ /releases/1998/10/981031181106.htm

5. Cultured lymphocytes from autistic children and non-autistic
siblings up-regulate heat shock protein RNA in response to thimerosal
challenge.Find More Like This
Authors:
Walker, Stephen J.1 swalker@wfubmc.edu
Segal, Jeffrey
Aschner, Michael2
Source:
NeuroToxicology; Sep2006, Vol. 27 Issue 5, p685-692, 8p

Subject Terms:
*AUTISTIC children
*TOXINS
*AUTISM
*METALS
*TOXICOLOGY
*HEAVY metals -- Physiological effect
*METALLOTHIONEIN

Abstract: There are reports suggesting that some autistic children
are unable to mount an adequate response following exposure to
environmental toxins. This potential deficit, coupled with the
similarity in clinical presentations of autism and some heavy metal
toxicities, has led to the suggestion that heavy metal poisoning
might play a role in the etiology of autism in uniquely susceptible
individuals. Thimerosal, an anti-microbial preservative previously
added routinely to childhood multi-dose vaccines, is composed of
49.6% ethyl mercury. Based on the levels of this toxin that children
receive through routine immunization schedules in the first years of
life, it has been postulated that thimerosal may be a potential
triggering mechanism contributing to autism in susceptible
individuals. One potential risk factor in these individuals may be an
inability to adequately up-regulate metallothionein (MT) biosynthesis
in response to presentation of a heavy metal challenge. To
investigate this hypothesis, cultured lymphocytes (obtained from the
Autism Genetic Resource Exchange, AGRE) from autistic children and
non-autistic siblings were challenged with either 10μM ethyl mercury,
150μM zinc, or fresh media (control). Following the challenge, total
RNA was extracted and used to query "whole genome" DNA microarrays.
Cultured lymphocytes challenged with zinc responded with an
impressive up-regulation of MT transcripts (at least nine different
MTs were over-expressed) while cells challenged with thimerosal
responded by up-regulating numerous heat shock protein transcripts,
but not MTs. Although there were no apparent differences between
autistic and non-autistic sibling responses in this very small
sampling group, the differences in expression profiles between those
cells treated with zinc versus thimerosal were dramatic. Determining
cellular response, at the level of gene expression, has important
implications for the understanding and treatment ... [Copyright 2006
Elsevier]

Copyright of NeuroToxicology is the property of Elsevier

6. An Evaluation of the Effects of Thimerosal on Neurodevelopmental
Disorders Reported Following DTP and Hib Vaccines in Comparison to
DTPH Vaccine in the United States.

Authors:
Geier, David A.1,2
Geier, Mark R.3 mgeier@comcast.net
Source:
Journal of Toxicology & Environmental Health: Part A; Aug2006, Vol.
69 Issue 15, p1481-1495, 15p
Document Type:
Article
Thimerosal is an ethylmercury (49.55% mercury by weight) preservative
historically added to some vaccines. Toxicokinetic studies showed
children in the United States received doses of mercury from
Thimerosal-containing vaccines (TCVs) in excess of safety guidelines.
In the United States during the 1990s, diphtheria-tetanus-pertussis
(DTP) and Haemophilus influenzae type b (Hib) vaccines (maximally, 50
μg mercury per joint administration) and diphtheria-tetanus-pertussis-
Haemophilus influenzae type b (DTPH) vaccines (25 μg mercury per
administration) were given to children in the same childhood
vaccination schedule at 2, 4, 6, and 15-18 mo, so that children
receiving DTP and Hib vaccines may have maximally received an
additional 100 μg more mercury exposure from TCVs than children
administered DTPH vaccines. A case-control epidemiological study of
neurodevelopmental disorders (NDs) reported to the Vaccine Adverse
Event Reporting System (VAERS) (online public access version; updated
31 August 2004) following administration of DTP vaccines in
comparison DTPH vaccines manufactured by Lederle Laboratories (Pearl
River, NY) from 1994 through 1998 was undertaken. Significantly
increased odds ratios for autism, speech disorders, mental
retardation, infantile spasms, and thinking abnormalities reported to
VAERS were found following DTP vaccines in comparison to DTPH
vaccines with minimal bias or systematic error. Additional ND
research should be undertaken in the context of evaluating mercury-
associated exposures, especially since in 2005 the Institute of
Medicine issued a report calling into question handling of vaccine
safety data by the National Immunization Program of the Centers for
Disease Control and Prevention. [ABSTRACT FROM AUTHOR]

7. Clinical & Experimental Immunology; Nov2005, Vol. 142 Issue 2,
p377-380, 4p
Document Type:
Article
Subject Terms:
*HEPATITIS B -- Vaccination
*HEPATITIS B vaccine
*ANTIPHOSPHOLIPID syndrome
*VACCINATION
*IMMUNOGLOBULINS

Author-Supplied Keywords:
autoimmunity
hepatitis B

NAICS/Industry Codes:
923120 Administration of Public Health Programs
Abstract:
This study was undertaken to evaluate the possible role of hepatitis
B recombinant vaccine inducing the synthesis of IgG and IgM anti-
cardiolipin antibodies (aCL), antibodies against β₂GPI
(anti-β₂GPI), lupus anti-coagulant (LA), anti-nuclear
antibodies and antibodies against extractable nuclear antigens (anti-
ENA). The study population consisted of 85 healthy students (63
female, 22 male; mean age 20•8 years), vaccinated with three doses of
recombinant DNA hepatitis B vaccine. One month after vaccination with
the first dose of hepatitis B vaccine a minority of vaccinated
individuals showed changes in IgG or IgM aCL or anti-β₂GPI
or LA activity ( P < 0•001). Among subjects in whom changes of IgG
anti-β₂GPI were observed, a significantly higher number of
increased (8/85) than decreased (2/85) values were found ( P < 0•01).
Analyses of paired data showed that differences in aCL or anti-
β₂GPI levels before vaccination or 1 month later did not
reach statistical significance. In two people aCL transitorily
reached medium positivity after the first dose of hepatitis B vaccine
with a drop 5 months later. Similar evident anti-β₂GPI
fluctuation was also observed in one person. Another participant was
initially low positive for IgG anti-β2GPI and the levels were
increasing after vaccination. Two participants became positive for
anti-nuclear antibodies during 6 months' follow-up. There were no sex-
dependent differences in tested antibodies observed and no
associations between levels of aPL and levels of anti-HBV antibodies.
We conclude that HBV can induce aPL, although rarely. In genetically
susceptible individuals or together with some other triggers such
combination might confer the risk of developing a continuous
autoimmune response in an individual. [ABSTRACT FROM AUTHOR]

8. Autoimmune hazards of hepatitis B vaccine.
Girard, Marc1 agosgirard@aol.com
Autoimmunity Reviews; Feb2005, Vol. 4 Issue 2, p96-100, 5p
Document Type:
Article
Subject Terms:
*SAFETY
*HEPATITIS B vaccine
*VIRAL vaccines
*EVIDENCE-based medicine
*EPIDEMIOLOGY

Author-Supplied Keywords:
Autoimmunity
Hepatitis B
Molecular mimicry
Vaccination

Abstract:
Abstract: According to Hippocratic tradition, the safety level of a
preventive medicine must be very high, as it is aimed at protecting
people against diseases that they may not contract. This paper points
out that information on the safety of hepatitis B vaccine (HBV) is
biased as compared to classical requirements of evidence-based
medicine (EBM), as exemplified by a documented selectivity in the
presentation or even publication of available clinical or
epidemiological data. Then, a review is made of data suggesting that
HBV is remarkable by the frequency, the severity and the variety of
its complications, some of them probably related to a mechanism of
molecular mimicry leading to demyelinating diseases, and the others
reproducing the spectrum of non-hepatic manifestations of natural
hepatitis B. To be explained, this unusual spectrum of toxicity
requires additional investigations based upon complete release of
available data.

9. 65% Autistic Children Found To Have Mitochondrial Disorder

At an American Academy of Neurology meeting last Sunday it was
revealed in a recent research paper, see below, that 65% of children with Austistic Spectrum Disorders assessed were found to have mitochondrial disorder (MtD) and so were always at risk of autism caused by one or more vaccines.

Oxidative Phosphorylation (OXPHOS) Defects in Children with Autistic
Spectrum Disorders [IN1-1.004]

John Shoffner, Lauren C. Hyams, Genevieve N. Langley, Atlanta, GA

OBJECTIVE: To retrospectively survey patients with autistic spectrum
disorders that were evaluated clinically for mitochondrial disease
and to
assess the
clinical and laboratory features of this group of patients.
BACKGROUND: Autism is a developmental disorder characterized by
disturbance
in language, perception and socialization. A variety of biochemical,
anatomical and neuroradiographical studies imply a disturbance of
brain energy metabolism in autistic patients. Recent studies confirmed the
previously reported high frequency of biochemical markers of mitochondrial dysfunction, namely hyperlactacidemia and increased lactate/pyruvate ratio, in a significant fraction of 210 autistic patients. (J Autism Dev Disord, 2006.
36:1137)
Although rare, Mecp2 mutations can produce autistic features and the mouse
model has significant mitochondrial defects. (Mol Cell Biol, 2006. 26: 5033)
Additionalgenetic defects associated with mitochondrial dysfunction include
inverted 15q11-13 duplication (Complex III defect) (Ann Neurol, 2003,53,801), A3243G mutation (mitochondrial transfer RNALeucine(UUR) gene, mtDNA depletion (J Pediatr, 2004,144,81), G8363A mutation (mitochondrial transfer RNALysine gene. (J Child
Neurol, 2000,15,357).
DESIGN/METHODS: Retrospective analysis of 37 children with autistic spectrum disorders. Clinical, biochemical, metabolic, and genetic data is
assessed.
RESULTS: Twenty four children (65%) had skeletal muscle OXPHOS
defects: Complex I (16), Complex I and Complex III (5), Complex III (1),
Complex I and Complex IV (2). Thirteen (35%) had normal skeletal muscle OXPHOS enzyme activities for Complexes I-IV. Clinical, metabolic, protein
chemistry, and sequencing of coding regions of the mitochondrial DNA will be reported.
CONCLUSIONS/RELEVANCE: Most children with autistic spectrum disorders
do not have recognizable abnormalities on a broad range of imaging,
metabolic and genetic studies. However, a subset of patients do harbor significant defects in oxidative phosphorylation function. Complex I abnormalities are the most frequently encountered defect. Recognition of these children is important for understanding how genes that produce autistic spectrum disorders impact mitochondrial function. Supported by: Horizon Molecular Medicine.
Category - Neurogenetics and Gene Therapy SubCategory - Other
Sunday, April 13, 2008 2:45 PM
Platform Session: Integrated Neuroscience: Autism (2:00 PM-3:15 PM)
Annual Meeting American Academy of Neurology"

Michael A. Gruttadauria, DC, DACAN
Defeat Autism Now! Clinician

Board Certified Chiropractic Neurology
100 Manetto Hill Road, Suite 106
Plainview, NY 11803
_www.lispectrum.com_ (http://www.lispectrum.com/)
516-470-9525 Office
516-470-9524 Fax

[RobinN]

A different community being HIT:

1) Some 10.4 million service members, DoD employees and their beneficiaries (including children) have been vaccinated.

2) Up to 2%, or 1-in-50 service members (and it looks like DoD employees and beneficiaries as well - though I have yet to confirm this) have sustained "serious" adverse vaccine reactions, including disability and death.

3) Among active duty and reserve service members, up to 48,000 individuals may have sustained serious vaccine injuries which might need to be classified as "casualties."

4) These vaccine-related disabilities are often severe, and may require teaching "new skills" to the injured.

At first, I thought the injury rates might be so high because of the anthrax and smallpox vaccines. But military studies on both shots claimed that they were extremely safe. (For example, there were only 140 reports of inflamed heart muscle following smallpox vaccination, out of 1.2 million service members vaccinated).

But then I read that the possible cause of so much injury, for service members at least, was "multiple vaccines" or "drugs + vaccines," according to the VHC slide.

I wrote to the VHC, and to the GAO, seeking more information on these data, but did not receive any replies (so far, although I will be happy to update this column if I do).

The questions raised by this, by other slides in the series, and within the GAO report, are numerous. They could have serious implications for the military, and for the population at large.

http://www.huffingtonpost.com/david-..._b_119048.html