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  #1  
Old 11-19-2007, 06:06 PM
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antihistamines and partial complex seizures


Does anyone here think they ever had a seizure because they took an antihistamine? I just read a book called Partial Seizure Disorders that mentions antihistamines as a possible cause of seizures.

In the past I had taken benadryl right before a couple of swim races so I could breath better and I had no problem. But in October I took a benadryl and I had a seizure 20 minutes later while I was driving. In the past I also have had seizures at night while I was sleeping and I often took Benadryl at night for my alergies.

Has anyone else ever wondered if taking an antihisamine caused a seizure for them?
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Old 11-19-2007, 08:15 PM
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Unhappy Yes!....definitely!......


Sudafed is an absolute killer for me! It seems to really lower my seizure threshhold (as if the presence of severe allergies isn't bad enough!).

I have settled on using Claritin to battle my allergies or toughing it out...the epileptologist said it won't interfere with Zonisamide(Zonegran) and Trileptal use.
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Old 11-19-2007, 10:20 PM
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Originally Posted by forward2007 View Post:
Does anyone here think they ever had a seizure because they took an antihistamine? I just read a book called Partial Seizure Disorders that mentions antihistamines as a possible cause of seizures.

In the past I had taken benadryl right before a couple of swim races so I could breath better and I had no problem. But in October I took a benadryl and I had a seizure 20 minutes later while I was driving. In the past I also have had seizures at night while I was sleeping and I often took Benadryl at night for my alergies.

Has anyone else ever wondered if taking an antihisamine caused a seizure for them?
No Wonder about it! I ended up in the ER on Benadryl and my pharmacist called my doc when she watched me fall out in the pharmacy after I'd taken a sudafed. Anihistimines and seizures\seizure meds are not a good combo.
Here's a link to more information:

Drugs that may lower seizure threshold : Epilepsy.com/ProfessionalsDrugs that may lower seizure threshold ... antihistamines baclofen heavy metals hyperbaric oxygen lithium mefenamic acid oral hypoglycemics ...
professionals.epilepsy.com/page/table_seniors_drugs.html
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Old 11-19-2007, 11:55 PM
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Zoe I tried to do a cut and paste on that link and it failed.

I am glad to know this, as a mom, I would reach for Sudafed as a sure bet.
Benadryl sent my ASD son into crazy mode as a young child. I was expecting sleepiness and he was bouncing off the walls, and that is putting it mildly.

Last edited by RobinN; 11-19-2007 at 11:58 PM.
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Old 11-20-2007, 08:10 AM
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Hi forward2007, welcome to the forum.
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New to CWE? I suggest reading the proactive prescription and epilepsy 101 threads. Also check out this chart of alternative epilepsy treatments and this page on EEG Neurofeedback. More great stuff can be found in the list of the best forum threads.

Would you like to help support this forum?
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Old 11-20-2007, 11:20 AM
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Oops!
Forward2007,I too want to welcome you to the forum. Glad you joined us.
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Old 11-20-2007, 07:13 PM
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Thanks for the welcome. I'll be posting lots of questions on the forum
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Old 11-20-2007, 10:44 PM
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Forward!

Looking forward to meeting you!


(Couldn't resist saying that!)
Welcome to CWE! And you're correct
in regarding to the meds and complex partial's.
I can't even take Nyquil or stuff
like that, and there goes my list of
No-No's ... and I feel like a 3 year
old sometimes! No, you can't have
this. No, you can't do that.

How about some Yes, I can do this?
Yes, I can take that?
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Old 11-26-2007, 08:20 PM
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Question


Would the same seizure threshold rule apply to cough syrup? My cough syrup (Wal-Mart brand) contains 6.25 mg antihistimine?
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Old 11-26-2007, 11:03 PM
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Forward2007,

I just had to add my piece, it's from an earlier post:

check with your pharmasist or Dr. but if you are on ANY anti-epileptic drugs, definately don't take any over the counter cold or flu meds (anything containing antihystimine and/or decongestant as the chemical reaction CAN be fatal.)

I speak from 28 years experience of being on anti-epileptic drugs.
I was told (and experienced myself) internal bleeding or nose bleeds from most headache meds exept Tylonol. That's the only one that I can take that doesn't react to my seizure meds.

I can't take aspirin, IB Profen, Advil, Exederin or Motrin, just Tylonol.

I took 2 Advil once by mistake and had massive nose bleeds that wouldn't stop. At the time I didn't think it had anything to do with the meds then it happened again just a couple of days before I had to see my neurologist. I happened to mention this to him and he was very concerned and said that I was lucky that I didn't bleed out through my stomach.

This is more of a problem in my case because I also take meds for my ulcerative colitis.

This warning is not documented on any OTC cold/flu meds literature.
I don't know why the FDA doesn't make this info manditory.

Regards

Randy
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Diagnosed with epilepsy and ulcerative colitis in 1979,
Been on meds ever since.

275mg-dilantin/day
120mg-pheonobarb/day
3,000mg-Mesasol/day
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Old 11-26-2007, 11:35 PM
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I keep trying to find some more info on this and can't seem to pull anything up.
Found some facts that antihistamines can trigger seizures, but nothing about internal bleeding.
Can anyone help pull something up?
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Old 11-26-2007, 11:53 PM
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My Neurologist told me that taking Benadryl would be safe as long as I followed the directions so I question how well known it is that antihistamines can cause seizures.
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Old 11-28-2007, 09:19 AM
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Originally Posted by forward2007 View Post:
My Neurologist told me that taking Benadryl would be safe as long as I followed the directions so I question how well known it is that antihistamines can cause seizures.
I had to take another dose of Benadryl last night i feel like crap today was sick to my stomach weak dizzy....

you guys might be right.... i see my neurologist again in January so ill ask him.... its not something I've ever taken a lot of ...

the rash is gone now though
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Old 11-28-2007, 09:24 AM
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Good to hear Angel... now drink your water today.
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Old 11-28-2007, 09:33 AM
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hehe ok mom i will ....
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Old 11-28-2007, 09:40 AM
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(it is a reminder for myself too...)
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Old 11-28-2007, 09:46 AM
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I know it is hard to drink water all the time.... I sometimes add lemon or lime just to have a different taste....
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Old 11-28-2007, 10:05 AM
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Just remembering is hard for me, but I am going to connect it to this machine, and won't allow myself to touch a key, until I have taken my glass and downed the contents.
(We are talking H20 here folks)
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Old 12-07-2007, 12:13 PM
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happened to me


I too had a seizure after backpacking in CO and taking an antihistimine. I have mentioned this to 3 nero docs and none of them had said anything -- so it is great to have the confirmation.
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Old 12-16-2007, 11:36 AM
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I went to the Dr. Friday and he was less than convinced that the seizure I had while driving was caused by the Benadryl I had taken twenty minutes before the seizure happened. He did agree I should play it safe though and switch to a different antihistamine.
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