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I take 80mg of B6 a day from a B complex pill and my Multi-Vitamin and I haven't had any problems. Both the B complex and the Multi-Vitamin are time-released.
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Also I am not sure if I wrote this before or not, forgive me if I have, but sometimes a vitamin or mineral needs another vitamin or mineral to be absorbed properly.
... My doctor told me to take Vitamin B6. ... My neurologist said it is necessary for Keppra. I will have to ask him why?