[Research] Cannibis Product Research Showing Positive Results for LGS

[Zoe]

This just came in the news. A trial using a cannibis product is showing good results in treating Lennox-Gastaut Syndrome (LGS)

"Topline Results Positive for Cannabidiol in Lennox-Gastaut
Pauline Anderson
June 27, 2016

Following release in March of positive topline results from a phase 3 trial of an investigational cannabidiol product (Epidiolex, GW Pharmaceuticals) in patients with Dravet syndrome, GW Pharmaceuticals has now announced more positive results, this time from a phase 3 study in patients with Lennox-Gastaut syndrome (LGS)."

Link to full article:

http://www.medscape.com/viewarticle/865452
:woot:

 

[Frink]

Link requires membership to read.

 

[Frink]

Link works now. Hmm.

 

[Bernard]

Here's a press release on the news:

...
Patients aged 2-55 years with a confirmed diagnosis of drug-resistant LGS currently uncontrolled on one or more concomitant anti-epileptic drugs (AEDs) were eligible to participate in this Phase 3, randomized, double-blind placebo-controlled trial. The trial randomized 171 patients into two arms, where Epidiolex 20mg/kg/day (n=86) or placebo (n=85) was added to current AED treatment. On average, patients were taking approximately 3 AEDs, having previously tried and failed an average of 6 other AEDs. The average age of trial participants was 15 years (34% were 18 years or older). The median baseline drop seizure frequency per month was 74.

The primary efficacy endpoint of this trial was a comparison between Epidiolex and placebo in the percentage change in the monthly frequency of drop seizures during the 14 week treatment period (2 week dose escalation period followed by 12 weeks of maintenance) compared to the 4 week baseline period before randomization. Drop seizures were defined as atonic, tonic and tonic-clonic seizures involving the entire body, trunk or head that led or could have led to a fall, injury, slumping in a chair or hitting the patient’s head on a surface. During the treatment period, patients taking Epidiolex achieved a median reduction in monthly drop seizures of 44 percent compared with a reduction of 22 percent in patients receiving placebo, and the difference between treatments was statistically significant (p=0.0135).
...

https://globenewswire.com/news-rele...the-Treatment-of-Lennox-Gastaut-Syndrome.html

 

[resaebiunne]

I'm considering trying CBD oil additives to ecig juice. I can't smoke on campus where I work, so I could probably take some CBD oil infused water or juice. Would be an interesting experiment for sure.