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Vision-Based Artificial Intelligence Technologies for Epilepsy Monitoring: Scoping Review and Taxonomy Development Study -
CONCLUSIONS: Vision-based AI technologies for epilepsy monitoring are still dominated by proof-of-concept and pilot evaluations, indicating a gap between technical feasibility and deployment-ready systems. This scoping review presents an implementation-oriented taxonomy integrating application context, system architecture, visual analysis, AI models, performance reporting, and feedback design i...
MRI Findings and Diagnostic Yield in Pediatric Epilepsy: A Cross-Sectional Study -
CONCLUSION: MRI is a valuable imaging modality for identifying structural abnormalities in pediatric epilepsy, with a higher diagnostic yield in patients with partial seizures. The findings underscore the importance of high-resolution MRI protocols in evaluating epilepsy, particularly in children with focal seizure presentations. Future studies should explore the integration of advanced imaging...
Efficacy and Safety of Cannabinoid-Based Products in Children and Adolescents with Autism Spectrum Disorder, Fragile X Syndrome and Rett Syndrome: A Systematic Review -
CONCLUSION: CBPs may offer potential benefits for selected behavioral symptoms and comorbid epilepsy in pediatric NDDs, but current evidence is insufficient to support routine clinical use. High-quality randomized controlled trials with standardized outcome measures and long-term follow-up are needed to clarify efficacy, safety, and syndrome-specific effects.
Aurora-Associated Geomagnetic Activity and Health: A Review With Focus on Neurological Implications -
Geomagnetic activity (GMA), particularly during auroras, has emerged as an intriguing area of research due to its potential health impact. Prior studies indicate that fluctuations in geomagnetic fields can affect diverse physiological and psychological outcomes. The aim of this article is to comprehensively review the impact of GMA on neurological health with an emphasis on implications for pat...
TPPU protects against seizures and seizure-associated comorbidities by inhibiting the Akt/mTOR signaling pathway in KA-induced convulsant mice -
CONCLUSIONS: Our findings establish the Akt/mTOR axis as a critical pathway mediating the protective actions of TPPU against epilepsy and its comorbidities in murine models. This work not only advances our understanding of epilepsy pathophysiology but also identifies novel targets for the development of comprehensive therapeutic strategies.
Neuroprotective activity of the α7-nAChR positive allosteric modulator PNU-120596 on short term outcomes after traumatic brain injury -
Traumatic brain injury (TBI) often leads to long-lasting neurological, cognitive, and behavioral impairments. Despite its high global burden, no disease-modifying therapies currently exist to mitigate secondary injury processes that contribute to chronic neurological deficits. Activation of α7 nicotinic acetylcholine receptors (α7-nAChRs), which are expressed on neurons, glia, and immune cells,...
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