Epilepsy News

Response to: "Early benzodiazepine treatment and electrographic seizures after febrile status epilepticus" - We appreciate Inui et al.'s comments regarding the divergent prognostic outcomes of patients with electrographic seizures (ESz) between our studies. The poorer prognosis in their cohort compared to ours likely stems from three key differences. First, baseline disease severity significantly differed. Our cohort predominantly consisted of milder cases, such as febrile seizures, with only 17.2% re...

Chronic posthypoxic myoclonus: Lance-Adams syndrome - Lance-Adams syndrome (LAS) is a rare condition described as chronic intentional myoclonus following prolonged hypoxia. With limited cases of the condition, no standardised diagnostic criteria, and features overlapping acute myoclonus status epilepticus (MSE), diagnosis and management are challenging.Our case is a man in his 20s, who was admitted to the intensive care unit following two in-hospi...

Comparative analysis of the effects of Δ9-tetrahydrocannabinol and cannabidiol on pilocarpine-induced status epilepticus in mice - There is growing interest in using cannabis and its active ingredients for epilepsy treatment. The main components of cannabis are cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), with some formulations of CBD approved for treating epilepsies refractory to traditional pharmacological treatments. However, it remains unclear whether the acute administration of THC or CBD can reverse a seizure...

Evaluating the usability and clinical outcomes of a mobile health application for epilepsy management in children: a quasi-experimental controlled study - CONCLUSIONS: Use of My Epilepsy App in addition to standard care was associated with reductions in seizure frequency and seizure duration and showed excellent parent-reported usability. However, these findings should be interpreted cautiously because the non-randomized design does not allow causal conclusions.

Living with medicine resistant epilepsy: Perspectives of a sample of Black Americans - CONCLUSIONS: The burden of MRE extends beyond seizure control to include emotional, social, and racialized dimensions. Establishing trust in clinical encounters requires integrating social and structural contexts into the planning of treatment and is essential for the delivery of equitable epilepsy care.

Burden assessment tools in epilepsy caregiving: A scoping review - CONCLUSIONS: While generic tools like the ZBI are reliable standards, epilepsy-specific tools provide more granular and contextually relevant assessments of the caregiver's lived reality. There is an urgent need to shift from literal translation to rigorous structural validation of tool reliability and validity, and to develop dedicated, epilepsy-specific instruments for adult populations.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.