Brivaracetam in Refractory Epilepsy: Mechanism, Tolerability, and Clinical Positioning -
Epilepsy is a common neurological disorder and has a considerable global impact. Established treatment options remain limited, as current antiseizure medications (ASMs) often do not adequately reduce the frequency of seizures. The standard of care for individuals with epilepsy using existing ASMs often fails to meet both the expectations of clinicians and patients. We observed that many ASMs ar...
Phenobarbital monotherapy for convulsive seizures in rural Northwest China: a 12-year longitudinal study -
CONCLUSIONS: Our study demonstrated that convulsive seizures could be effectively controlled with PB monotherapy with mild adverse effects in rural areas in Northwest China. Early treatment response, particularly seizure freedom within the first two years, is a strong indicator of long-term remission. High baseline seizure frequency is an independent risk factor for poor prognosis.
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes -
New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
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