Epilepsy News

CREATe Therapeutics Achieves Complete Seizure Prevention in a Severe Model of Focal Epilepsy - Breakthrough Preclinical Result in Epilepsy Treatment These findings strengthen our confidence as we progress toward ...

After Epilepsy Surgery, When to Stop ASMs Matters - A multicenter cohort study explores how the timing of ASM withdrawal after epilepsy surgery may influence seizure relapse and long-term outcomes.

Longboard Pharma Trial Data Show How It Could Stand Out in the Epilepsy Field - Longboard Pharmaceuticals is chasing much bigger companies already in the market with therapies for rare forms of epilepsy. The biotech has gone from saying its drug could be differentiated to ...

Focal treatment-resistant epilepsy symptoms improved with antiseizure medication - Please provide your email address to receive an email when new articles are posted on . Monthly seizure frequency percentage reduction was 68.73% for the entire study cohort. For those followed up in ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Pediatrics in Brevard: Here's what to know about epilepsy, what to do if someone has seizure - More than 3.4 million people in the United States have epilepsy, so it is a relatively common diagnosis. In fact, it is the fourth-most common neurologic condition in the world. November is National ...

Understanding epilepsy: Seven ways to respond to an epileptic seizure - At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...

Why Early Detection of Seizures and Epilepsy Is so Important - For parents, a child having a seizure is one of the most frightening experiences imaginable. While many childhood seizures are brief and isolated, others are more serious and persistent. To make the ...

Rewiring Your Brain: Neurofeedback Goes Mainstream - Will Strahl walked up to my door with a massive black briefcase in his hand, the kind you could use to tote a dirty bomb. Once inside my living room, he cracked open the case and removed a laptop, a ...

Neurofeedback Gains Popularity and Lab Attention - You sit in a chair, facing a computer screen, while a clinician sticks electrodes to your scalp with a viscous goop that takes days to wash out of your hair. Wires from the sensors connect to a ...

Neurofeedback for ADHD: Significant, Lasting Improvement - Computer-based neurofeedback can produce significant and lasting improvement in attention and focus in children with attention-deficit/hyperactivity disorder (ADHD ...

Can Monitoring Brain Waves Boost Mental Health? - Neurofeedback has promised a mental health revolution for decades. But is it effective? Credit...Tony Luong for The New York Times Supported by By David Dodge Twice a week, Stephanie, a 37-year-old ...

Neurofeedback is the newest mental health hack among entrepreneurs. Here’s why - Running a business can be an exhilarating and rewarding journey, but it can also bring a unique set of stressors. While the beginning stages of a business can be exciting and feel full of ...

Safety and efficacy of eslicarbazepine acetate for seizure prevention in patients with stroke at high risk of developing post-stroke epilepsy: a proof-of-concept, phase 2a, randomised, double-blind... - BACKGROUND: Eslicarbazepine acetate is an antiseizure medication that has shown potential antiepileptogenic effects in preclinical models of epilepsy. We aimed to investigate whether eslicarbazepine acetate could prevent or reduce the incidence of unprovoked seizures after acute ischaemic stroke or acute intracerebral haemorrhage.

A step towards antiepileptogenic therapies for post-stroke epilepsy - No abstract

Efficacy and safety of cenobamate-based combination therapy in drug-resistant epilepsy: Secondary analysis by mechanisms of action of concomitant antiseizure medications - CONCLUSION: Cenobamate demonstrated optimal efficacy when combined with valproate and broad-spectrum agents, and suboptimal efficacy when coadministered with SCB. Substantial seizure improvements were often achieved at moderate doses of cenobamate, underscoring the value of individualized titration and comedication management.

Image-guided posterior callosotomy: Optimizing disconnection with DTI tractography and neuronavigation - CONCLUSION: Integrating DTI-based tractography with neuronavigation in posterior callosotomy is feasible and safe, and significantly enhances surgical precision. This approach allows the targeted transection of motor callosal fibers, leading to superior seizure control and stable or improved cognitive outcomes, thereby validating the mechanistic role of these pathways in drop attacks. We advoca...

Dose escalation in pentylenetetrazol kindling detects differences in chronic seizure susceptibility - Pentylenetetrazol (PTZ) kindling is a widely used model for inducing epileptogenesis and evaluating long-term seizure susceptibility differences among animals. This model is typically performed by chronic, repetitive exposures to a constant subconvulsive PTZ dose. However, the effectiveness of the commonly used dose (35 mg/kg) varies among different animal groups due to factors such as species,...

The protective effect of planned pregnancy against adverse foetal outcomes in pregnant women with epilepsy: A retrospective cohort analysis from Northwest China - CONCLUSION: Planned pregnancy is associated with well folic acid adherence, proactive ASM adjustment, higher breastfeeding rates, and stable seizure control. It serves as an independent protective factor against adverse foetal outcomes. Maternal age ≥ 30 years, TPM use, and frequent GTCS increase risk, while ASM withdrawal during pregnancy is not protective.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.