Epilepsy News

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Focal treatment-resistant epilepsy symptoms improved with antiseizure medication - Please provide your email address to receive an email when new articles are posted on . Monthly seizure frequency percentage reduction was 68.73% for the entire study cohort. For those followed up in ...

Understanding epilepsy: Seven ways to respond to an epileptic seizure - At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...

EPILEPSY AWARENESS: Local neurologist explains condition & seizure first aid - COLUMBUS, Ga. (WRBL) — Local experts say epilepsy is not a condition to be afraid of. Piedmont Columbus Regional pediatric neurologist Pierre Fequiere treats patients with epilepsy every day and knows ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

Multiscale predictive modeling robustly improves the accuracy of pseudo-prospective seizure forecasting in drug-resistant epilepsy - Extensive research over the past two decades has focused on identifying a preictal period in scalp and intracranial encephalography (iEEG). This effort has led to numerous seizure prediction and forecasting algorithms, with moderate success on datasets consisting of curated and pre-segmented EEG. When evaluated pseudo-prospectively on continuous EEG recordings, existing algorithms often exhibit...

Attributional bias in epilepsy: Differences between genetic generalised epilepsy, temporal lobe epilepsy and healthy controls - CONCLUSIONS: These findings suggest that some individuals with genetic generalised epilepsy are more likely to interpret ambiguous situations as hostile. Altered attributional style may represent an under-recognised factor contributing to social difficulties in people with epilepsy and warrants further investigation as a potential target for psychosocial interventions.

Seizure outcomes after primary brain tumor resection in adults: Experience of two tertiary centers in Saudi Arabia - CONCLUSION: Approximately half of patients achieved seizure freedom for at least 1 year after surgical resection. Tumor recurrence and frequent preoperative seizures were associated with a higher risk of postoperative seizures. ASM withdrawal may be feasible in selected patients with stable low-risk disease using careful risk stratification.

Localization of ictal fear and related brain network - CONCLUSIONS: These findings delineate the regional and network-level electrophysiological features associated with IF. IF is not attributable to a single anatomical substrate but is instead linked to abnormal engagement of distributed limbic-prefrontal networks, with a core connectivity pattern centered on hippocampus-anterior cingulate interactions. Adopting a network-based perspective may fac...

Pregnancy outcomes following Eslicarbazepine acetate exposure in women with epilepsy: A global safety database analysis from clinical development to 16 years of post-marketing experience - CONCLUSIONS: Across all years with ESL exposure, no consistent pattern of congenital disorders or miscarriages was observed in pregnant women with epilepsy. While large safety databases support signal detection, there remains a need for high‑quality, adequately powered observational studies and continued pharmacovigilance to guide informed clinical decision‑making in this vulnerable population.

Integrating multisequence radiomics and clinical features to predict seizure recurrence after gross total resection of pediatric low-grade epilepsy-associated brain tumors - CONCLUSION: The combined model of multimodal MRI radiomics and clinical features demonstrates potential for predicting postoperative seizure outcomes in pediatric LEAT patients after GTR.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.