Epilepsy and Seizure News
The Campaign for a National Plan for Epilepsy Needs Your Help -
A future neurologist appeals for your support for the National Plan for Epilepsy to coordinate research and care to enable earlier diagnosis, better treatment, and hopefully a cure.
Seizure action plans: Management and educational tools in epilepsy care -
Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...
Seizure action plans: More than management tools for epilepsy -
Newswise — Historically, seizure action plans have focused on certain high-risk groups — such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters ...
Epilepsy Advocacy Network provides resources, plans fundraiser -
One in 26 people will develop epilepsy in their lifetime, and one 1 in 10 people will have a seizure. November is just around the corner, and that is Epilepsy Awareness Month. Carrie Jones and Kim ...
Patients engage with epilepsy monitor in real time, improving seizure detection -
A team has built an AI-based interface that enables real-time communication between patients and epilepsy monitoring devices. As part of a small clinical study at the University of Pennsylvania in ...
Epilepsy Explained: Causes, Seizure Types, and Treatment Options for Better Control -
Egyptian fruit bats flew more slowly after eating alcohol-laced food. Now the urine strips that caught boozy wild chimps may be used on wild bats. Teen Heart Health Scores Average 68.3 in Ninth Grade ...
First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week -
Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...
Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? -
Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...
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Mechanisms of Seizure Generation and SUDEP in Cortical Dysplasia: A Role for Cortical Up and Down States -
Sudden unexpected death in epilepsy (SUDEP) remains the primary cause of epilepsy-related mortality, yet the preictal brain dynamics that distinguish fatal from nonfatal seizures are not well understood. Identifying the network mechanisms determining these outcomes is critical for developing SUDEP risk biomarkers. Using a neuron-specific PTEN knockout mouse model of cortical dysplasia-which exh...
Modulation of Postictal Hypoxia: Sex- and Route-Specific Effects of Acute and Chronic Cannabidiol and Delta9-tetrahydrocannabinol -
Postictal hypoxia causes several consequences that are detrimental to the quality of life of people with epilepsy. Cannabidiol (CBD) and Δ⁹-tetrahydrocannabinol (THC), the primary phytocannabinoids from cannabis, have been shown to exhibit vasoactive and antioxidant properties that may mitigate the local oxygen deficiency observed after seizures. Here, we focus on the effects of CBD and THC on ...
Reduced inhibition of hippocampal adult-born granule cells by parvalbumin interneurons after TBI -
Traumatic brain injury (TBI) is one of the leading causes of acquired temporal lobe epilepsy. TBI drives hippocampal circuit rearrangements that may contribute to increased seizure risk, such as altered inhibitory circuit function and aberrant post-traumatic neurogenesis. In the hippocampal dentate gyrus, adult-born dentate granule cells (DGCs) acquire inhibitory synaptic inputs from parvalbumi...
Anticonvulsant activity of berberine: a systematic review and meta-analysis of preclinical studies in animal models -
CONCLUSION: Berberine exerts a consistent, dose-dependent, multi-target anticonvulsant effect that is greatly enhanced by nanoformulation. Certainty was moderate for the primary outcome and low-moderate elsewhere, defining berberine as a rational candidate for further translational development in epilepsy.
Tablet crushing, but not splitting, alters the pharmacokinetics of extended-release levetiracetam in dogs -
CONCLUSIONS: Splitting LEV-XR tablets did not significantly alter the evaluated pharmacokinetic parameters, whereas crushing resulted in a higher Cmax, an earlier model-estimated Tmax, and reduced late exposure.
Knowledge, self-management, and health-related quality of life among Omani adults with generalized epilepsy: A cross-sectional study -
CONCLUSION: Omani adults with epilepsy exhibit poor knowledge, only acceptable self-management skills, and low HR-QoL. The positive association between knowledge and HR-QoL highlights the need to strengthen epilepsy-related education. Culturally tailored educational and self-management support for patients, families, and the wider public is required to improve knowledge, optimize self-managemen...
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