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Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review -
OBJECTIVE: A systematic review was conducted to synthesize current anatomo-clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence-based guidance for interpreting this ictal semiology during presurgical evaluation.
Prevalence of neuropsychiatric and seizure disorders in neurofibromatosis type 1: a systematic review and meta-analysis -
Neurofibromatosis type 1 (NF1) is associated with intellectual disability (ID), autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), emotional and seizure disorders. However, published prevalence estimates vary widely. The aim of this meta-analysis was to estimate the prevalence of ID, ASD, ADHD, epileptic seizures and emotional disorders in NF1. A systematic search ...
The role of MEG cluster characteristics in defining the epileptogenic zone: A retrospective study of 101 seizure-free patients -
OBJECTIVE: Magnetoencephalography (MEG) is used widely in presurgical evaluation of medically intractable epilepsy. Prior research has documented the added value of MEG in refining surgical strategies; however, not all MEG clusters require resection for seizure freedom, suggesting that they represent nodes within a broader epileptic network, with differing importance for epileptogenic zone (EZ)...
Low-gamma wavelet entropy as a contextual signature descriptor of the epileptogenic zone in peri-onset SEEG -
CONCLUSION: The proposed method enables accurate and interpretable identification of epileptogenic contacts, with potential for patient-level screening pending validation on larger datasets.
Electrical Stimulation With stereoelectroencephalography for Defining the Surgical Target: A Contemporary Approach -
This review aims to summarize important concepts related to electrical stimulation for the induction of seizures as it is understood in 2026. We discuss the history of electrical stimulation; we describe important methodological considerations when stimulating; we review key recent publications regarding the clinical validity of stimulated seizures; and we mention emerging areas of interest and...
Nanostructured lipid carriers for intranasal cannabidiol delivery in Dravet and Lennox-Gastaut syndromes: bridging preclinical promise to clinical translation -
Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS) are severe developmental epileptic encephalopathies that appear in early childhood, are unresponsive to medications, and have a dismal neurodevelopmental prognosis. Most patients do not respond well to polytherapy, and the need to fulfill this gap in clinical practice is urgent. Cannabidiol (CBD) has proven to be an effective adjunct drug, ...
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