Epilepsy News

New fMRI neurofeedback study trains the brain to reduce depressive rumination - Major Depressive Disorder (MDD) is far from a cookie-cutter diagnosis. Different patients report suffering from different subsets of symptoms, yet most are ultimately prescribed the same first-line ...

Rewiring Your Brain: Neurofeedback Goes Mainstream - See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Will Strahl walked up to my door with a massive black briefcase in his ...

What Is Neurofeedback Therapy And How Does It Work? - Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...

Neurofeedback Trains Brain to Stop Depressive Rumination - A new study uses real-time fMRI neurofeedback to help depression patients reduce rumination by training specific brain circuits in a gamified environment.

Neurofeedback Gains Popularity and Lab Attention - You sit in a chair, facing a computer screen, while a clinician sticks electrodes to your scalp with a viscous goop that takes days to wash out of your hair. Wires from the sensors connect to a ...

Endoscopic endonasal depth EEG-guided resection of a temporal encephalocele resulting in seizure freedom: illustrative case - BACKGROUND: Temporal encephaloceles (TEs) are increasingly recognized as epileptogenic lesions in drug-resistant temporal lobe epilepsy. However, endoscopic endonasal surgery performed primarily to resect epileptogenic lesions remains extremely rare, largely because defining the optimal extent of resection is challenging without direct electrophysiological confirmation.

Child Neurology: Expanding the LGI1 Spectrum: Homozygous Loss-of-Function Variant in an Infant With Epileptic Encephalopathy - Epilepsy syndromes are clinically defined by their specific set of features, including seizure types, age at onset, electroencephalographic patterns, and prognosis. For example, autosomal-dominant lateral temporal lobe epilepsy (ADLTE) is a well-recognized epilepsy syndrome associated with heterozygous leucine-rich glioma inactivated-1 (LGI1) gene variants. Relatedly, developmental and epilepti...

The functional impact of LGI1 autoantibodies on human CA3 pyramidal neurons - Autoantibodies against leucine-rich glioma inactivated 1 protein (LGI1) lead to limbic encephalitis, a rare neurological autoimmune disorder characterized by faciobrachial dystonic seizures and memory deficits. While animal models provide precious insights into the mechanisms of LGI1 autoantibody action, species-specific confirmation is lacking. In this study, we investigated the effects of pat...

Neuropsychiatric adverse effects associated with the use of levetiracetam in adults: A Systematic Review and Meta-analysis - CONCLUSION: Patients treated with levetiracetam have a greater risk of developing neuropsychiatric effects, such as somnolence and fatigue, compared to placebo.

Neuroimaging spectrum of GATOR1-related epilepsy (GATORopathies) - CONCLUSION: GATOR1-related epilepsy demonstrates substantial variability in neuroimaging and electroclinical features, extending beyond focal cortical malformations to include diffuse cortical malformations, generalized neuroparenchymal atrophy, and MRI-negative presentations. These findings highlight the value of integrated genetic, imaging, and electroclinical assessment in routine clinical p...

Comparative Predictive Performance of Serum and Dose-Normalized Valproate Levels for Seizure Control in Adults With Epilepsy - Background Valproate is a widely used antiepileptic drug, but its clinical response shows considerable interindividual variability. Conventional therapeutic ranges may not reliably predict seizure control, and the role of dose-normalized valproate levels in forecasting seizure as an outcome remains unclear. Objective To evaluate the predictive performance of serum valproate levels for seizure c...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.