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Intraventricular hemorrhage, suspected EBV reactivation, and TBA-positive epilepsy after deep cervical lymphovenous anastomosis in Alzheimer's disease: a case report -
Lymphovenous anastomosis (LVA) is emerging as a potential surgical intervention to ameliorate cervical lymphatic outflow and enhance glymphatic clearance in Alzheimer's disease (AD). However, the spectrum of neurological sequelae associated with this procedure remains poorly characterized. We report the case of a 67-years-old male with amyloid PET-confirmed AD who underwent bilateral deep cervi...
Attitudes and misconceptions surrounding epilepsy and first aid of seizures in the Eastern Mediterranean Region: a systematic review and meta-analysis -
No abstract
Adjunctive antiepileptic efficacy and safety study of mTOR inhibitors in children with tuberous sclerosis complex -
CONCLUSION: Adjunctive therapy with mTOR inhibitors improves the response rate to antiepileptic treatment in children with TSC, with sirolimus and everolimus demonstrating comparable efficacy. Therapeutic benefits were observed regardless of seizure onset age, and longer treatment duration was associated with greater efficacy. mTOR inhibitors may cause some adverse effects in children, but most...
Deletion of Alg13 disrupts postnatal development and migration of GABAergic cortical interneurons -
CONCLUSION: Alg13 regulates postnatal interneuron development, and its deletion may contribute to epilepsy-related pathophysiology. These results enhance understanding of the molecular mechanisms underlying epilepsy and provide a potential experimental foundation and novel therapeutic targets for the management of Alg13-associated refractory seizures, thereby advancing knowledge of interneuron ...
KCNQ2 Variants in Neonatal Epilepsy: Clinical Characteristics and Neurodevelopmental Outcomes in 30 Patients -
BACKGROUND AND OBJECTIVES: The aim of this study was to characterize clinical features, genetic architecture, treatment responses, and neurodevelopmental outcomes in neonatal epilepsy associated with KCNQ2 variants and to delineate genotype-phenotype correlations.
Ciprofloxacin-induced microbiota dysbiosis triggers seizure susceptibility through the microbiota-gut-brain axis -
CONCLUSION: This study provides evidence linking gut microbiota dysbiosis to seizure susceptibility through neuroinflammatory processes, contributing to the understanding of gut-brain axis involvement in fluoroquinolone-induced seizures.
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