Epilepsy News
Recent news about epilepsy, seizures and treatments.
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The second unprovoked seizure in a cohort of treated patients with a first unprovoked seizure -
OBJECTIVES: To evaluate the rate of a second unprovoked seizure in antiseizure medications (ASMs)-treated patients following a first unprovoked seizure and to identify potential risk factors associated with its occurrence.
Determinants of accuracy in frame-based stereoelectroencephalography: the role of experience, workflow, and selective use of guiding devices - CONCLUSION: Frame-based sEEG implantation demonstrates high accuracy and safety. Deviations were predominantly minor and clinically acceptable, Accuracy appears primarily determined by surgical experience and workflow standardization rather than adjunctive devices. Selective cannula use may be reasonable in technically demanding trajectories, but routine application does not confer measurable b...
Mapping the cognitive landscape: a pilot study of domain-specific outcomes following frontal lobe resection in children with epilepsy - CONCLUSION: This pilot study demonstrates the feasibility and clinical value of domain-specific cognitive assessment, revealing heterogeneous outcomes not captured by global measures. The exploratory findings generate specific hypotheses regarding the roles of ASM management, developmental timing, baseline cognition, and surgical laterality. These results provide a foundation for larger, prospe...
Case Report: Epilepsy-related pure word deafness in the elderly: an underreported presentation? - We describe a rare case of epilepsy-related PWD in the elderly. A 61-year-old right-handed man presented with status epilepticus. Although electroencephalogram revealed no epileptiform discharges, brain magnetic resonance imaging (MRI) showed hyperintensity in the left temporoparietal lobe and thalamic pulvinar on diffusion-weighted imaging (DWI). Cerebrospinal fluid revealed no pleocytosis and...
Knowledge and Attitudes of Teachers and School Professionals Toward Epilepsy: Results of an Educational Program in Greece - CONCLUSIONS: The interactive training program had a positive impact on overall knowledge and attitudes; however, coordinated efforts by the entire educational community and health organizations are recommended to implement specialized training and guidance programs for teachers.
Epm2bP71A and Epm2bD148N knock-in mouse models of Lafora disease exhibit distinct and pronounced neurological alterations - Lafora disease is a rare, autosomal recessive neurodegenerative disorder characterized by the progressive accumulation of abnormal, insoluble, and hyperphosphorylated forms of glycogen, known as Lafora bodies, in the brain and other tissues. The disease typically manifests during early adolescence with myoclonus, seizures, and rapidly progressive cognitive decline, ultimately leading to severe ...
Determinants of accuracy in frame-based stereoelectroencephalography: the role of experience, workflow, and selective use of guiding devices - CONCLUSION: Frame-based sEEG implantation demonstrates high accuracy and safety. Deviations were predominantly minor and clinically acceptable, Accuracy appears primarily determined by surgical experience and workflow standardization rather than adjunctive devices. Selective cannula use may be reasonable in technically demanding trajectories, but routine application does not confer measurable b...
Mapping the cognitive landscape: a pilot study of domain-specific outcomes following frontal lobe resection in children with epilepsy - CONCLUSION: This pilot study demonstrates the feasibility and clinical value of domain-specific cognitive assessment, revealing heterogeneous outcomes not captured by global measures. The exploratory findings generate specific hypotheses regarding the roles of ASM management, developmental timing, baseline cognition, and surgical laterality. These results provide a foundation for larger, prospe...
Case Report: Epilepsy-related pure word deafness in the elderly: an underreported presentation? - We describe a rare case of epilepsy-related PWD in the elderly. A 61-year-old right-handed man presented with status epilepticus. Although electroencephalogram revealed no epileptiform discharges, brain magnetic resonance imaging (MRI) showed hyperintensity in the left temporoparietal lobe and thalamic pulvinar on diffusion-weighted imaging (DWI). Cerebrospinal fluid revealed no pleocytosis and...
Knowledge and Attitudes of Teachers and School Professionals Toward Epilepsy: Results of an Educational Program in Greece - CONCLUSIONS: The interactive training program had a positive impact on overall knowledge and attitudes; however, coordinated efforts by the entire educational community and health organizations are recommended to implement specialized training and guidance programs for teachers.
Epm2bP71A and Epm2bD148N knock-in mouse models of Lafora disease exhibit distinct and pronounced neurological alterations - Lafora disease is a rare, autosomal recessive neurodegenerative disorder characterized by the progressive accumulation of abnormal, insoluble, and hyperphosphorylated forms of glycogen, known as Lafora bodies, in the brain and other tissues. The disease typically manifests during early adolescence with myoclonus, seizures, and rapidly progressive cognitive decline, ultimately leading to severe ...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.