Epilepsy and Seizure News
Nerve Stimulation for Epilepsy: Intracranial Versus Extracranial Approaches Compared -
But long-term mortality -- which her group considered a proxy for seizure control -- became substantially worse for patients treated with VNS compared with the intracranial implants, starting at about ...
GLP-1s Linked to Better Seizure Control in Epilepsy -
GLP-1s are linked to lower seizure recurrence, hospitalization, and mortality risk than other glucose-lowering drugs in adults with epilepsy, new research shows.
First seizure clinic speeds time to diagnosis with pediatric epilepsy -
Children referred to a first seizure clinic (FSC) see a neurologist epilepsy specialist within one week, according to a study presented at the annual meeting of the American Epilepsy Society, held ...
RAP-219 Phase 2a Seizure Data and Planned Pivotal Trials Might Change The Case For Investing In Rapport Therapeutics (RAPP) -
Rapport Therapeutics recently presented new data and post hoc analyses from its Phase 2a trial of RAP-219 in drug-resistant focal onset seizures at the 2025 American Epilepsy Society Meeting, showing ...
NeuroVice Announces PATI Now Available, Launches First FDA-Cleared Device Designed for Seizure Oral Injury Protection and Airway Management at American Epilepsy Society Annual ... -
Today, NeuroVice announced that PATI is now commercially available, marking a breakthrough moment for millions of patients living with focal and grand-mal seizures. The company will debut the ...
OHSU epilepsy patient nearly seizure-free after regenerative brain cell therapy procedure -
PORTLAND, Ore. — Oregon Health and Science University is at the forefront, again, of a possible life-changing medical advancement. “I think this is a turning point. This is where I’m hopeful that ...
Xenon Showcases New 48-Month Azetukalner OLE Study Data in Epilepsy at AES 2025 -
Monthly reductions in seizure frequency of 90.9% among participants treated for ≥48 months in the OLE, with 38% achieving ≥1 year of seizure ...
Many people have seizures. Here's why that doesn’t always mean epilepsy. -
One of the most common causes of epilepsy is a structural brain abnormality. “Epilepsy can result from structural issues in the brain, such as brain tumors, brain injuries, brain infections or ...
Praxis claims efficacy success in phase 2 seizure trial, setting up approval talks with FDA -
“SCN2A and SCN8A DEEs are devastating conditions with extremely high mortality due to the debilitating seizure burden they impose on patients, and there are currently no approved treatment options,” ...
Epilepsy awareness in the workplace: training and safety tips -
More than 35,000 Long Islanders live with epilepsy. Experts urge businesses to provide seizure training, safety plans, and awareness to protect employees and customers.
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Non-invasive neurostimulation for drug-resistant epilepsy: systematic review and meta-analysis of effectiveness, safety, and optimal stimulation parameters -
Drug-resistant epilepsy is a common and disabling condition, with few non-surgical treatment options. Non-invasive neurostimulation is an emerging therapy for drug-resistant epilepsy, though evidence is mixed and comparisons between modalities remain challenging. This review systematically appraises and compares the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS)...
Temporal Dynamics of c-Fos Expression in a Zebrafish Larva Model of Pentylenetetrazole-Induced Seizures -
The use of zebrafish (Danio rerio) larva as an experimental model has gained a lot of interest in epilepsy research due to its multiple advantages over mammalian models. The present study investigated the time-dependent expression of c-fos, an immediate early gene, and a marker of neuronal activation, following pentylenetetrazole (PTZ)-induced seizures in zebrafish larvae at 7-day post-fertiliz...
Early neurological symptoms and epilepsy outcomes in individuals with the recurrent GABRG2 p.(Ala106Thr) gain-of-function variant: Structural and phenotypic insights -
OBJECTIVE: Variants in GABRG2, encoding the γ2 subunit of the γ-aminobutyric acid type A receptor, are linked to epilepsy phenotypes of varying severity, with gain-of-function (GoF) variants associated with the more severe phenotypes than loss-of-function variants. Here, we provide a comprehensive analysis of the early clinical features, motor, language, and eating abilities, and structural con...
Detection of interictal epileptiform discharges using multiple bilateral insertions of a newly developed microcatheter-compatible endovascular electroencephalogram electrode: A clinical feasibility... -
OBJECTIVE: To assess the feasibility, technical performance, and safety of a novel endovascular electroencephalogram (eEEG) electrode, EP-01, designed for minimally invasive seizure localization in patients with drug-resistant epilepsy.
Multiscale network perspectives on glioma: from tumour biology to symptoms, survival and treatment -
Adult glioma is associated with a wide range of symptoms and variable survival that are not fully explained by tumour location or subtype. Recent work suggests that the disease may be better understood using a network-based framework, as opposed to more traditional localizationist thinking. In this Review, we describe three major types of network scaffolds relevant in people with glioma: sympto...
Lightweight Seizure Prediction Model based on Kernel-Enhanced Global Temporal Attention -
Clinically, epilepsy manifests as a chronic condition marked by unprovoked, recurrent seizures, plaguing over 70 million individuals with debilitating seizures and life-threatening complications. Approximately 30% of patients with epilepsy do not respond to conventional antiepileptic drugs, indicating the limited efficacy of these medications in controlling seizures universally. Therefore, seiz...
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