Epilepsy and Seizure News
Many people have seizures. Here's why it doesn’t always mean epilepsy -
Here’s what epilepsy is, what causes it and how it’s treated if it affects you or someone you love.
'I just felt like me': West MI woman's journey from epilepsy to seizure-free life -
Taylor Hyma's journey from enduring drug-resistant epilepsy to becoming seizure-free after brain surgery highlights hope and challenges for patients.
Late-Onset Epilepsy a Distinct Neurodegenerative Subtype? -
Emerging clinical and autopsy evidence points to late-onset epilepsy as a potentially distinct, neurodegeneration-related form of epilepsy, with many cases still unexplained.
‘First Seizure Clinic’ for Pediatric Epilepsy a Model of Success -
A dedicated pediatric “one-stop” First Seizure Clinic cuts wait times to under a week and enables earlier diagnoses, giving families faster answers and more streamlined care.
AES: First Seizure Clinic Speeds Time to Diagnosis With Pediatric Epilepsy -
Children referred to a first seizure clinic often see a neurologist epilepsy specialist within 1 week for timely diagnosis and treatment.
GLP-1 Drugs Linked to Lower Epilepsy Risk in Diabetes Patients -
GLP-1 receptor agonists were tied to a 16% lower risk of epilepsy in adults with type 2 diabetes. Epilepsy is an underrecognized comorbidity in people with type 2 diabetes, the researchers noted.
Durham family, desperate to help 3-year-old with severe epilepsy, fundraising for seizure alert dog -
Doctors diagnosed Finley with epilepsy. No one else in the Mullen family has the seizure disorder, and Ashley and Will worked to learn as much as possible about it and document Finley’s ...
Experts warn TikTok epilepsy care videos can be misleading -
Fake clickbait TikTok videos about epilepsy treatments are receiving more views than accurate, evidence-based offerings, a new study says.
Xenon Showcases New 48-Month Azetukalner OLE Study Data in Epilepsy at AES 2025 -
Detailed price information for Xenon Pharmaceuticals Inc (XENE-Q) from The Globe and Mail including charting and trades.
Ozempic Shows a Possible Hidden Effect on Epilepsy Risk -
Popular GLP-1 medications such as Ozempic may carry an unexpected link to a lower risk of epilepsy in people with type 2 diabetes.
Neurofeedback News
Mindmachines.com Advances Meditation Technology with Third-Generation RoshiWave Mind Machine and Enhanced Gadgets -
Mindmachines.com has unveiled the third generation of its RoshiWave IN-SIGHT Mind Machine, introducing advanced neurofeedback technology designed to help users achieve deep meditative states through ...
Rewiring Your Brain: Neurofeedback Goes Mainstream -
Will Strahl walked up to my door with a massive black briefcase in his hand, the kind you could use to tote a dirty bomb. Once inside my living room, he cracked open the case and removed a laptop, a ...
Mindmachines.com Unveils Advanced RoshiWave Mind Machine for Enhanced Mental Wellness Through Neurofeedback Technology -
Mindmachines.com has introduced the third generation of its RoshiWave IN-SIGHT Mind Machine, a mental wellness device that employs Dynamic Neuro-Activation technology to help users achieve meditative ...
Neurofeedback as a Treatment for Parkinson’s Disease -
April was Parkinson’s Awareness Month, which prompted me to share this story and an effective, yet little-known treatment for Parkinson’s disease (PD). Parkinson’s disease is a form of brain disorder, ...
Neurofeedback Gains Popularity and Lab Attention -
You sit in a chair, facing a computer screen, while a clinician sticks electrodes to your scalp with a viscous goop that takes days to wash out of your hair. Wires from the sensors connect to a ...
Medical News Today
PubMed
Proteome profiling of cerebrospinal fluid-derived extracellular vesicles reveals potential biomarkers for drug-resistant epilepsy -
CONCLUSIONS: Proteins with differential abundance studied here are associated with epilepsy due to their potential involvement in critical processes such as neuroprotection, inflammation, cell integrity, and immune response. The observed reduction in the abundance of these proteins in drug-resistant dogs suggests that disruptions in these processes may contribute to the severity of the conditio...
Calcium-Activated Potassium Channel KCa3.1 Shape Epileptiform Discharges in the Rodent Entorhinal Cortex -
The mechanisms underlying the generation and termination of epileptic discharges remain incompletely understood. This study investigates the role of K(Ca)3.1 (KCNN4) channels in modulating epileptiform activity in the deep layers of the entorhinal cortex using two in vitro models: short-lasting late recurrent discharges (LRDs) and prolonged tonic-clonic seizure-like events (SLEs). Whole-cell pa...
Syngap1 and the development of murine neocortical progenitor cells -
SYNGAP1 regulates synaptic plasticity through interactions with scaffold proteins and modulation of Ras and Rap GTPase signaling. Human SYNGAP1 mutations are linked to intellectual disability, epilepsy, and autism. In mice, Syngap1 haploinsufficiency causes impaired LTP, premature maturation of dendritic spines, learning disabilities, and seizures, reflecting the human phenotypes of SYNGAP1 syn...
Juvenile/adult-onset POLG-related disease unmasked by valproate-associated fulminant hepatic failure -
DNA polymerase subunit gamma-1 (POLG)-related disease is a heterogeneous spectrum of mitochondrial disorders with neurologic and hepatic manifestations. We report a woman in her 20s who developed refractory seizures followed by fulminant hepatic failure after valproic acid exposure. Laboratory evaluation revealed low copper indices without evidence of Wilson disease, neuroimaging demonstrated e...
The anti-epileptic mechanism of a ketogenic diet regulating the gut microbiota via SIRT2 activation of the PI3K/AKT signaling pathway -
CONCLUSION: The anti-epileptic effect of KD in the prefrontal cortex is associated with the activation of the PI3K/Akt signaling pathway and an increase in SIRT2 expression. Additionally, our data are consistent with the emerging concept that the anti-seizure effects of KD may also involve modulation of the gut microbiota. This provides valuable insights for the development of new therapeutic i...
Loss of presenilin 2 function age-dependently increases susceptibility to kainate-induced acute seizures and blunts hippocampal kainate-type glutamate receptor expression -
Presenilin 2 (PSEN2) variants increase risk of Alzheimer's disease (AD) and unprovoked seizures. Yet, age-related PSEN2 contributions to seizure susceptibility are understudied. Critically, PSEN proteolytic capacity may regulate hippocampal kainate-type glutamate receptor (KARs) availability. Kainic acid (KA) is a KAR agonist that evokes severe seizures in mice. We hypothesized that PSEN2 knock...
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