Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? -
Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...
Can Neurofeedback Effectively Treat ADHD? -
Neurofeedback training is an alternative therapy that uses real-time EEG data to help patients train their brains to improve focus, impulse control, and executive function. Since the 1970s, patients ...
What Is Neurofeedback Therapy? -
Neurofeedback is a noninvasive form of therapy that trains the brain to improve various neurological issues, including chronic pain, ADHD, anxiety, depression and PTSD. Using EEG to monitor real-time ...
How virtual reality is changing brain-training technology -
Integrating virtual reality into brain-training therapies can make the experience more enjoyable and engaging for users. A recent review published in the journal Applied Psychophysiology and ...
Testing a brain training device for better focus sleep and relaxation -
A detailed review of a neurofeedback headband exploring how brain training technology works and the creator’s experience using it for focus relaxation sleep and mental performance. #Neurofeedback #Men ...
Medical News Today
PubMed
Reduced inhibition of hippocampal adult-born granule cells by parvalbumin interneurons after TBI -
Traumatic brain injury (TBI) is one of the leading causes of acquired temporal lobe epilepsy. TBI drives hippocampal circuit rearrangements that may contribute to increased seizure risk, such as altered inhibitory circuit function and aberrant post-traumatic neurogenesis. In the hippocampal dentate gyrus, adult-born dentate granule cells (DGCs) acquire inhibitory synaptic inputs from parvalbumi...
Parvalbumin interneurons and dentate gyrus homeostatic dysregulation shape epileptogenesis in Angelman syndrome model mice -
Understanding how neural circuits transition from seizure-resistant to seizure-prone is essential for developing improved epilepsy therapies. Here, we study this process by leveraging the heightened susceptibility to seizure kindling of Angelman syndrome (AS) model mice, which lack the maternal Ube3a (mUbe3a) allele. We identify parvalbumin-expressing (PV+) interneurons as critical gatekeepers;...
mTORC1 drives cell-autonomous astrocyte reactivity in tuberous sclerosis -
Tuberous sclerosis complex (TSC) is a genetic neurodevelopmental disorder characterized by focal brain malformations called cortical tubers, which are associated with severe, intractable epilepsy¹. Tubers are thought to result from somatic second-hit mutations that disrupt the TSC1 or TSC2 genes in neural progenitor cells, driving hyperactive mTORC1 signalling². Glial abnormalities are commonly...
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes -
New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
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