Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Epilepsy and Seizure News
What to know about epilepsy and seizure first aid -
November is Epilepsy Awareness Month. Many people may already be aware of the condition from its prevalence in medical dramas, but that portrayal is often exaggerated and does not fully encapsulate ...
What Is Epilepsy Surgery? - Medications can control seizures in most people with epilepsy, but they don’t work for everyone. About 30% of people taking the drugs can’t tolerate the side effects. In some cases, brain surgery may ...
What Is Epilepsy Surgery? - Medications can control seizures in most people with epilepsy, but they don’t work for everyone. About 30% of people taking the drugs can’t tolerate the side effects. In some cases, brain surgery may ...
Medical News Today
PubMed
Knowledge graph representation of the mappings between seizure semiology and epileptogenic zones -
Precise epileptogenic zone (EZ) localization remains challenging for epilepsy surgery planning. While seizure semiology provides valuable localization information, subjective interpretation and inter-observer variability limit clinical utility. We developed a computational framework utilizing knowledge graph architectures to analyze ictal semiology-EZ relationships systematically. We constructe...
Elevated FKBP5 expression associates with epilepsy-related molecular changes and promotes neuronal hyperexcitability - CONCLUSION: These findings suggested that FKBP5 played a significant role in regulating neuronal excitability and extracellular glutamate homeostasis. However, due to discrete sampling and the lack of continuous seizure monitoring, the present in vivo data do not establish a definitive causal contribution of FKBP5 to epileptogenesis, warranting future studies integrating longitudinal EEG and ce...
Targeted gene panel testing in pediatric epilepsy: Diagnostic outcomes and expanding genetic insights - CONCLUSION: Epilepsy gene panel testing is a valuable diagnostic tool in pediatric clinical practice. The identification of pathogenic variants across a wide range of genes - including a high proportion of novel mutations - supports the integration of genetic testing into the routine evaluation of pediatric epilepsy for improved etiological clarification and long-term management.
Nationwide registry-linked retrospective cohort study of Ganglioglioma in children and adults: Long-term follow-up of anti-seizure medication and mortality - CONCLUSIONS: This study demonstrates that long-term ASM discontinuation after ganglioglioma surgery is negatively associated with increasing age. ASM discontinuation is the same for those undergoing surgery in an epilepsy surgery program as for those who do not. Future studies are needed to explore why older patients are less likely to discontinue ASM treatment after ganglioglioma surgery.
Drug-resistant temporal lobe epilepsy: Seizure outcome in children versus adults - CONCLUSION: Children benefit more from TLE surgery than adults, due to earlier intervention and shorter duration of seizures. The principle of "time is brain" holds true in epilepsy; prolonged duration of uncontrolled seizures fosters network expansion, highlighting the need for "early surgical referral" and "catching them young."
Eye patches and seizure frequency in young people with Sunflower syndrome - The goal of this study was to assess the impact of wearing an eye patch on seizure frequency in patients with Sunflower syndrome, a reflex photosensitive epilepsy. Caregivers were instructed to record the number of handwaving episodes (HWEs) that occurred per hour under each of the following conditions: (1) no eye patch, (2) wearing an eye patch on the eye ipsilateral to the hand involved in ha...
Elevated FKBP5 expression associates with epilepsy-related molecular changes and promotes neuronal hyperexcitability - CONCLUSION: These findings suggested that FKBP5 played a significant role in regulating neuronal excitability and extracellular glutamate homeostasis. However, due to discrete sampling and the lack of continuous seizure monitoring, the present in vivo data do not establish a definitive causal contribution of FKBP5 to epileptogenesis, warranting future studies integrating longitudinal EEG and ce...
Targeted gene panel testing in pediatric epilepsy: Diagnostic outcomes and expanding genetic insights - CONCLUSION: Epilepsy gene panel testing is a valuable diagnostic tool in pediatric clinical practice. The identification of pathogenic variants across a wide range of genes - including a high proportion of novel mutations - supports the integration of genetic testing into the routine evaluation of pediatric epilepsy for improved etiological clarification and long-term management.
Nationwide registry-linked retrospective cohort study of Ganglioglioma in children and adults: Long-term follow-up of anti-seizure medication and mortality - CONCLUSIONS: This study demonstrates that long-term ASM discontinuation after ganglioglioma surgery is negatively associated with increasing age. ASM discontinuation is the same for those undergoing surgery in an epilepsy surgery program as for those who do not. Future studies are needed to explore why older patients are less likely to discontinue ASM treatment after ganglioglioma surgery.
Drug-resistant temporal lobe epilepsy: Seizure outcome in children versus adults - CONCLUSION: Children benefit more from TLE surgery than adults, due to earlier intervention and shorter duration of seizures. The principle of "time is brain" holds true in epilepsy; prolonged duration of uncontrolled seizures fosters network expansion, highlighting the need for "early surgical referral" and "catching them young."
Eye patches and seizure frequency in young people with Sunflower syndrome - The goal of this study was to assess the impact of wearing an eye patch on seizure frequency in patients with Sunflower syndrome, a reflex photosensitive epilepsy. Caregivers were instructed to record the number of handwaving episodes (HWEs) that occurred per hour under each of the following conditions: (1) no eye patch, (2) wearing an eye patch on the eye ipsilateral to the hand involved in ha...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.