Epilepsy News

Watch Out! A Few Minutes of Seizure May Mean Years of Mental Health Risk - Post-seizure psychosis may be linked to a higher risk of future psychiatric disorders in people with epilepsy.

Using Seizure-Risk Forecasts to ID Best Time for Epilepsy Monitoring - NASHVILLE, Tennessee ― Scheduling video-electroencephalography (vEEG) monitoring on the basis of personalized seizure risk forecasts may improve diagnostic accuracy, emerging research suggests. In a ...

Seizure first aid, epilepsy awareness bill signed into law - Legislation aimed at helping South Carolina workplaces respond appropriately when someone experiences a seizure has been signed into law by Gov. Henry McMaster.

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

In people with epilepsy, sleeping after a seizure may trigger more seizures - Add Yahoo as a preferred source to see more of our stories on Google. A new study suggests that the memory-forming stage of sleep could be key for understanding epileptic seizures. . | Credit: ...

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

Corpus callosotomy in Lennox-Gastaut syndrome: Effectiveness, safety, and predictors of outcome: A systematic review and meta-analysis - BACKGROUND: Lennox-Gastaut syndrome (LGS) is a severe, drug-resistant developmental and epileptic encephalopathy for which corpus callosotomy (CC) can be a particularly effective option for seizure control. However, this benefit must be weighed against the tradeoff of permanent corpus callosum disconnection. Although use of CC declined with the rise of neuromodulation, interest has resurged wit...

Prevalence of epilepsy and seizures in frontotemporal dementia: a systematic review and meta-analysis - Seizures and epilepsy are increasingly recognized in neurodegenerative diseases, yet their burden in frontotemporal dementia (FTD) remains poorly defined. We conducted a systematic review and meta-analysis to estimate the prevalence of epilepsy or seizures in FTD, assess comparative risk versus controls, and explore variation across clinical subtypes. MEDLINE/PubMed, Embase, Cochrane Library, L...

Idiopathic generalized epilepsy: biases and inconsistencies - OBJECTIVES: Distinguishing Idiopathic Generalized Epilepsy (IGE) from focal epilepsy (FE) can be challenging when IGE cases present with asymmetric clinical or electroencephalographic (i.e., atypical) features. We aimed to identify factors that lead to discordance in IGE diagnoses among epileptologists.

Characterizing Epileptic Network Dynamics with Koopman Operator: Toward Surgical Targeting of Seizure Onset Zones - Accurate localization of the seizure onset zone (SOZ) is essential for the surgical treatment of drug-resistant epilepsy, yet it remains challenging because seizures involve rapid and variable spatiotemporal reorganization of brain networks. In this study, we propose a Koopman-inspired dynamic graph (KDG) framework for SOZ localization from intracranial electroen cephalography (iEEG). Unlike co...

Invasive Neuromodulation of Drug-Resistant Epilepsy in Pediatric Populations: A Comprehensive Systematic Review and Meta-Analysis - CONCLUSIONS: VNS, RNS, and DBS provide meaningful seizure reduction with favorable safety profiles in pediatric DRE, though seizure freedom remains uncommon. Treatment selection should be individualized on the basis of epilepsy characteristics, age, and practical considerations.

Pediatric developmental epileptic encephalopathies treated with cenobamate: Real-world outcomes across etiologies, syndromes, and seizure types - OBJECTIVE: This study was undertaken to assess cenobamate (CNB) effectiveness, tolerability, and dosing in pediatric developmental and epileptic encephalopathies (DEEs), testing prespecified hypotheses on response by syndrome, etiology, electroencephalographic pattern, seizure type, CNB dose (mg/kg/day), and concomitant medication.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.