Epilepsy News

Azetukalner linked to sustained seizure reduction in focal onset epilepsy - Individuals with focal onset epilepsy treated with azetukalner experienced sustained monthly seizure reduction and evidence of seizure freedom up to 48 months, according to data presented at the ...

Many people have seizures. Here's why it doesn’t always mean epilepsy - One of the most common causes of epilepsy is a structural brain abnormality. “Epilepsy can result from structural issues in the brain, such as brain tumors, brain injuries, brain infections or ...

First seizure clinic speeds time to diagnosis with pediatric epilepsy - Children referred to a first seizure clinic (FSC) see a neurologist epilepsy specialist within one week, according to a study presented at the annual meeting of the American Epilepsy Society, held ...

The Evolving Landscape of Epilepsy Diagnosis and Management - During this symposium, leading international epileptologists discussed the key challenges and opportunities that currently exist ...

Pyridoxine-dependent early onset seizures associated with rare gene mutations: A case series - Pyridoxine dependent epilepsy (PDE) is a rare autosomal recessive disorder. Several genes involved in Pyridoxine (B6) metabolism have been implicated in the pathogenesis of PDE, two such genes are Aldehyde Dehydrogenase 7 Family Member A1 (ALDH7A1) and Pyridox(am)ine 5'- phosphate oxidase (PNPO). To add to the limited data on PDE, three cases of Vitamin B6 dependent neonatal epilepsy caused by ...

Epileptic Tears: Two Cases of Ictal Crying with Intracranial Correlates - Dacrystic seizure is a rare phenomenon of crying during an epileptic episode. It has an established connection to hypothalamic hamartoma, but was also reported to be associated with frontal and temporal epileptic foci. We present two cases of dacrystic epilepsy. Patient 1 had suffered from magnetic resonance imaging-negative epilepsy that was characterized by both gelastic and dacrystic seizure...

Connectivity between the seizure onset zone and the thalamus correlates with seizure outcomes in thalamic responsive neurostimulation - OBJECTIVE: Thalamic responsive neurostimulation (RNS) is a surgical option for patients with drug-refractory epilepsy. However, it is unclear whether thalamic connectivity with the seizure onset zone (SOZ) has a role in clinical outcomes. Here, we aim to investigate the clinical utility of the connectivity between the SOZ and the thalamus for thalamic RNS targeting.

Effects of vagus nerve stimulation and epilepsy surgery on antiseizure medication usage in pediatric patients with drug-resistant epilepsy in the real world: A retrospective nationwide cohort study - OBJECTIVE: The long-term effects of epilepsy surgery (ES) or vagus nerve stimulation (VNS) on antiseizure medication (ASM) usage and status epilepticus (SE) diagnosis in real-world pediatric drug-resistant epilepsy (DRE) populations remain unclear. This study aimed to provide a more comprehensive understanding of how VNS and ES affect ASM usage and SE manifestations in pediatric DRE.

Frontal Lobe Neurocysticercosis Presenting With Seizures and Anxiety: A Case Report Highlighting Radiological-Psychological Dimensions - Neurocysticercosis (NCC) is a major cause of acquired epilepsy in endemic regions. While seizures are the predominant manifestation, psychological distress is often underrecognized and rarely quantified in single-lesion cases. We describe the case of a 20-year-old male from rural India with a six-month history of recurrent generalized tonic-clonic seizures, accompanied by social withdrawal and ...

Fenfluramine for seizures associated with Dravet syndrome and Lennox-Gastaut syndrome - No abstract

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.