Epilepsy News

Patients engage with epilepsy monitor in real time, improving seizure detection - A team has built an AI-based interface that enables real-time communication between patients and epilepsy monitoring devices. As part of a small clinical study at the University of Pennsylvania in ...

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

NEURELIS TO PRESENT ANALYSES OF STUDY DATA FROM PEDIATRIC PATIENTS WITH SEIZURE CLUSTERS AT THE CHILD NEUROLOGY SOCIETY ANNUAL MEETING - Neurelis, Inc., a neuroscience company focused on the development and commercialization of therapeutics for the treatment of epilepsy ...

Seizure action plans: More than management tools for epilepsy - Newswise — Historically, seizure action plans have focused on certain high-risk groups — such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

Epigenetics and epilepsy - Epilepsy is one of the most prevalent neurologic conditions, affecting about 82 million persons worldwide. Epilepsy is characterized by spontaneous recurrent convulsive or nonconvulsive seizures. Most epilepsies in adulthood are acquired and can be traced back to an initiating injurious event to the brain, such as a traumatic brain injury, stroke, status epilepticus, or viral brain infection. E...

Patients with hemispheric epilepsy: Electroclinical characteristics and factors associated with intractability - CONCLUSIONS: The outcome of hemispheric epilepsy is largely determined by the type of brain lesion, with MCDs and Rasmussen encephalitis conferring the highest risk for intractability. In contrast, static acquired lesions were more often associated with better seizure control.

Short-term heart rate variability is associated with seizure outcome in drug-resistant temporal lobe epilepsy - We examined whether standard 5-minute heart rate variability (HRV) derived from interictal EEG-ECG recordings is associated with postoperative seizure outcome in drug-resistant temporal lobe epilepsy (TLE). Forty surgical TLE patients were studied before and after resection. Patients with persistent disabling seizures showed greater postoperative reductions in SDNN, RMSSD, LF, and HF power than...

Beyond seizure control: Non-seizure-related outcomes in focal-onset epilepsy treated with adjunctive cenobamate. Third interim results from the BLESS study - OBJECTIVE: Cenobamate is approved for treatment of focal seizures in adults, but evidence on non-seizure outcomes remains limited. This interim statistical analysis of the cenoBamate in aduLts with focal-onsEt SeizureS (BLESS) study evaluated patient- and clinician-reported outcomes for up to 52 weeks of cenobamate treatment.

Change in clobazam pharmacokinetics after introduction of cenobamate - Cenobamate is a new antiseizure medication with an unusually high seizure-free rate, resulting in frequent use in patients with drug-resistant epilepsy. Many of these patients are taking clobazam (CLB) at baseline. Cenobamate has important interactions with CLB, requiring CLB dose adjustment in conjunction with cenobamate titration. There is limited guidance on the optimal CLB dose adjustment a...

Temporal association between adjunctive repetitive transcranial magnetic stimulation and seizure reduction in a pediatric patient with DNM1L-associated EMPF1: a case report - CONCLUSIONS: In this case, adjunctive rTMS applied alongside standard antiepileptic and metabolic "cocktail" therapy was temporally associated with a pronounced reduction in seizure frequency in a patient with DNM1L-associated EMPF1. This temporal association is hypothesis-generating and does not permit attribution of the observed seizure reduction to rTMS; further investigation in larger cohor...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.