Epilepsy News

Parents sue OpenAI, alleging GPT-4o coached their daughter off seizure medication - A family is suing OpenAI, saying ChatGPT coached their daughter to quietly taper off her seizure medication and keep it from her doctors before she died in February.

The Campaign for a National Plan for Epilepsy Needs Your Help - A future neurologist appeals for your support for the National Plan for Epilepsy to coordinate research and care to enable earlier diagnosis, better treatment, and hopefully a cure.

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Parents sue OpenAI over ChatGPT advice to cut daughter’s seizure drug - A wrongful death suit alleges GPT-4o coached Bowen Wan, 31, to taper off her epilepsy medication before she died in February.

Seizure action plans: More than management tools for epilepsy - Newswise — Historically, seizure action plans have focused on certain high-risk groups — such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters ...

Early diagnosis and advanced surgical treatments can help epilepsy patients lead seizure-free lives - Apollo Hospitals expert calls for expanded awareness early referrals and dedicated CSR access fund to help drug resistant epilepsy patients overcome treatment barriers ...

Comparative efficacy of first-line antiseizure monotherapy in pediatric focal epilepsy: An umbrella review of systematic reviews and meta-analyses - CONCLUSIONS: Current umbrella-level evidence does not establish clear superiority of one first-line ASM over another for seizure control in pediatric focal epilepsy. Importantly, the absence of statistically significant differences should not be interpreted as evidence of therapeutic equivalence, because several estimates remain imprecise and clinically meaningful differences cannot be excluded...

Clinical efficacy and cost-effectiveness of epilepsy surgery in low- and middle-income countries: A systematic review and meta-analysis - OBJECTIVE: To synthesize evidence on clinical outcomes, direct surgical costs, and cost-effectiveness of resective epilepsy surgery for drug-resistant epilepsy in low- and middle-income countries (LMICs).

Accuracy, Safety, and Workflow of Frameless Neuronavigation-Guided Stereoelectroencephalography in Drug-Resistant Epilepsy: A Single-Center Cohort Study - CONCLUSION: Frameless neuronavigation-guided SEEG achieved reproducible millimetric accuracy, low morbidity, and efficient workflow in a consecutive real-world cohort. These findings support frameless neuronavigation as a safe and scalable option for invasive presurgical evaluation in DRE.

Neonatal-onset developmental and epileptic encephalopathy: High genetic yield and long-term outcomes in a multicenter southern European cohort - OBJECTIVE: To determine the genetic diagnostic yield, characterize the clinical and genetic landscape, and evaluate long-term epilepsy, neurodevelopmental, and survival outcomes in a strictly defined cohort of neonatal-onset developmental and epileptic encephalopathy (DEE).

Unilateral Approach for Bilateral Posterior Cingulate Coverage in Stereoelectroencephalography: A Technical Note and Case Series - CONCLUSION: We have shown that the unilateral transhemispheric approach for bilateral PCC SEEG is feasible to sample both sides. Importantly, the transfalcine approach used, and previously considered a relative contraindication, was performed safely and accurately in our series. We demonstrated the utility of sampling both ipsilateral and contralateral PCC to identify the epilepsy network. Thus...

Phenotypic comparison of idiopathic epilepsy in English Springer Spaniels and Cocker Spaniels using a validated owner-completed questionnaire - In response to the recurring identification of medication-resistant idiopathic epilepsy (IE) in English Springer Spaniels (ESS), the objective of this retrospective questionnaire-based observational study was to delineate the phenotypic characteristics of IE in this breed in comparison to a cognate breed, the English Cocker Spaniel (ECS), employing a novel, validated, owner-completed multilingu...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.