Epilepsy News

How Neurofeedback Can Help Troubled Couples Get Back on the Same Wavelength - Dr. David Helfand (left) with a patient. The cap contains 19 electrodes that measure the brain’s electrical activity. Credit: Courtesy When a 10-year romantic relationship ended last spring for ...

Neurofeedback game helps patients with MS manage fatigue - A compassionate neurofeedback game that can identify fatigue aims to help patients with MS, according to a poster presented at Cedars-Sinai’s eighth annual iteration of its Virtual Medicine Conference ...

What is neurofeedback? Video game-like therapy being used to treat anxiety, ADHD and more - It’s like a gym for your brain. As issues like anxiety, depression and restless sleep have spiked during the pandemic, some people are turning to neurofeedback, a kind of gym for the brain. It’s a ...

Neurophysiological Biomarkers and Targeted Neuromodulation in Major Depressive Disorder and Bipolar Disorder - Major depressive disorder (MDD) and bipolar disorder are among the leading causes of disability worldwide. However, their pathophysiological mechanisms ...

Neurofeedback gets you back in the zone - Researchers have shown -- for the first time -- that they can use online neurofeedback to modify an individual's arousal state to improve performance in a demanding sensory motor task, such as flying ...

Neuropharmacological, Analgesic, and Anti-Inflammatory Activities of Pothos scandens Acetone Extract With GC-MS-Based Phytochemical Profiling - Pothos scandens, belonging to the Araceae family, locally known as "batilata," is traditionally used for treating various chronic diseases in folk medicine, such as epilepsy, seizures, convulsions, wounds, snakebites, skin issues, asthma, muscle problems, and diarrhea. This research examined the anxiolytic, antidepressant, analgesic, and anti-inflammatory potentials of the acetone extract of P....

Single-cell Raman spectroscopy detects pediatric focal cortical dysplasia - CONCLUSIONS: The Raman spectroscopy signature of single cells associated with FCD tissue was established. This provides credence to the hypothesis that Raman spectroscopy as a technique-if implemented using a fiber optics system-has the potential for safely optimizing the extent of FCD type II resection in pediatric focal epilepsy surgery. In addition, this technique provides insights into mult...

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post-Hippocampectomy Dynamics - Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug-resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal hippocampal resection. Postoperative electrocorticograp...

Clec7a promotes hippocampal microglial activation in rats with status epilepticus via inducing the TLR4/MyD88/NF-κB signaling pathway - Microglial polarization imbalance between pro-inflammatory M1 and anti-inflammatory M2 phenotypes is a key mechanism in epilepsy-related neuroinflammation. This study explores the role of C-type lectin domain containing 7A (Clec7a) in M1 microglial polarization in epilepsy. An AAV-shClec7a was injected intra-hippocampally into Sprague-Dawley rats prior to induction of status epilepticus (SE) us...

Different connectivity patterns of MRI-negative drug-resistant epilepsy and drug-sensitive epilepsy in cerebellar and subcortical-cortical regions - Controlling cerebellar output may reduce seizure frequency. However, the involvement of the cerebellum in the development of drug resistance remains unclear. This study aims to elucidate the cerebellar-subcortical/cortical connectivity in drug resistance mechanisms using a multimodal approach. We utilized connectivity to select moderation and mediation models to further investigate the contact ...

Screening for serum antineuronal antibodies in pediatric epilepsy - CONCLUSION: Routine serum screening with standard commercial antibody panel did not identify neuronal antibodies in this pediatric cohort with chronic focal epilepsy. APE score distinguished patients with possible immune etiologies, suggesting that validated clinical scoring systems assist in selecting patients who may benefit from antibody screening in clinical practice.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.