Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Atypical Pediatric Epilepsy: A Narrative Review of Classification, Diagnosis, and Emerging Therapeutics -
Atypical pediatric epilepsies represent a heterogeneous group of disorders characterized by uncommon etiologies, variable clinical presentations, and frequent resistance to standard antiseizure medications. Recent advances in classification, along with developments in genomics, neuroimaging, and autoimmune neurology, have expanded the recognized spectrum of these conditions. However, a signific...
Long-Term Drop-Seizure Response Patterns to Cannabidiol According to Genetic Status in Lennox-Gastaut Syndrome - CONCLUSION: Long-term drop-seizure response to CBD in LGS was sustained but not stratified by genetic status, supporting a syndrome-level treatment approach irrespective of genetic findings.
Adjunctive perampanel in children with focal-onset seizures and developmental delay or intellectual disability: efficacy, tolerability, and sleep benefits - CONCLUSION: Adjunctive PER demonstrated favorable effectiveness and tolerability in children with focal-onset seizures and DD/ID despite substantial drug resistance and was also associated with improvement in sleep disturbance.
Involvement of the Claustrum in Human Epileptic Seizures - CONCLUSIONS: Our study suggests that the claustrum is often involved during seizures arising from the temporal lobe and cingulate cortexes and could play a role in modulation of the epileptogenic network.
Brain Research Bulletin NF-kappaB as a context-dependent inflammatory regulator of glial programs in epilepsy - Neuroinflammation is increasingly recognized as an important contributor to epileptogenesis and seizure recurrence, with microglia and astrocytes serving as major regulators of the inflammatory microenvironment. Among the pathways implicated in glia-mediated inflammation, nuclear factor kappa B (NF-κB) occupies a central position by integrating danger signals, metabolic stress, and activity-dep...
Utilizing wearable activity trackers to promote physical activity in people with epilepsy: a randomized controlled trial - OBJECTIVE: To evaluate exercise education alone versus exercise education in combination with a wearable physical activity tracker in people with epilepsy (PWE) to determine the effect on physical activity and measure potential impact on depression, anxiety, sleep, and quality of life (QoL).
Long-Term Drop-Seizure Response Patterns to Cannabidiol According to Genetic Status in Lennox-Gastaut Syndrome - CONCLUSION: Long-term drop-seizure response to CBD in LGS was sustained but not stratified by genetic status, supporting a syndrome-level treatment approach irrespective of genetic findings.
Adjunctive perampanel in children with focal-onset seizures and developmental delay or intellectual disability: efficacy, tolerability, and sleep benefits - CONCLUSION: Adjunctive PER demonstrated favorable effectiveness and tolerability in children with focal-onset seizures and DD/ID despite substantial drug resistance and was also associated with improvement in sleep disturbance.
Involvement of the Claustrum in Human Epileptic Seizures - CONCLUSIONS: Our study suggests that the claustrum is often involved during seizures arising from the temporal lobe and cingulate cortexes and could play a role in modulation of the epileptogenic network.
Brain Research Bulletin NF-kappaB as a context-dependent inflammatory regulator of glial programs in epilepsy - Neuroinflammation is increasingly recognized as an important contributor to epileptogenesis and seizure recurrence, with microglia and astrocytes serving as major regulators of the inflammatory microenvironment. Among the pathways implicated in glia-mediated inflammation, nuclear factor kappa B (NF-κB) occupies a central position by integrating danger signals, metabolic stress, and activity-dep...
Utilizing wearable activity trackers to promote physical activity in people with epilepsy: a randomized controlled trial - OBJECTIVE: To evaluate exercise education alone versus exercise education in combination with a wearable physical activity tracker in people with epilepsy (PWE) to determine the effect on physical activity and measure potential impact on depression, anxiety, sleep, and quality of life (QoL).
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.