Epilepsy News

Epilepsy characteristics and outcomes in patients with pleomorphic xanthoastrocytomas - CONCLUSIONS: Most patients with PXA-associated tumor-related epilepsy achieved seizure freedom after initial resection. Seizure recurrence was strongly associated with tumor recurrence at long-term follow up. ATRX loss was associated with seizure freedom at the most recent follow up, suggesting that tumor molecular features may help prognosticate epilepsy outcomes. Nearly one-third of patients ...

Reversible ipsilateral triple-region diffusion restriction after post-traumatic status epilepticus - This is a Neuro-Images submission. Per the journal's Instructions for Authors, Neuro-Images articles do not require an abstract. A brief summary is provided below for indexing purposes: A 41-year-old man with post-traumatic epilepsy developed status epilepticus after self-discontinuing antiseizure medications for two months. Brain MRI demonstrated simultaneous diffusion restriction in the right...

'To improve is to change'-but is it safe? A single surgeon's transition from lateral to vertical hemispherotomy - CONCLUSION: This study demonstrates that a single experienced epilepsy surgeon can safely transition between techniques, without compromising on seizure freedom outcomes or incurring additional morbidity. Whilst larger studies may demonstrate the favourability of one technique over the other, it may be useful to the individual surgeon to have a sound grasp of both techniques in their armamentar...

Hyperkinetic Seizures in Insular and Insulo-Opercular Seizure Onset: A Systematic Review - ObjectiveTo describe demographics, semiology, etiology, and clinical features in individuals with insulo-opercular and pure insular onset presenting with hyperkinetic seizures (HKS).MethodsUnder PRISMA guidelines, Embase, PubMed, Medline, and Cochrane were searched for articles between 1969 and January 10, 2025, using terms for hyperkinetic/hypermotor seizures, insular epilepsy, sleep-related h...

Automatic Seizure Detection using Hierarchical Spectral-Temporal Feature Learning with an Imbalance-Aware Transformer - Epilepsy manifests as a chronic neurological condition marked by recurrent seizures. Recent advances in computational analysis of Electroencephalography (EEG) signals have enabled new possibilities for identifying ictal events in extended recordings. This work develops a novel deep learning architecture that simultaneously resolves two fundamental challenges in automated seizure detection: comp...

Qualitative EEG morphology predicts early Antiseizure medication response in newly diagnosed epilepsy: A prospective cohort study - CONCLUSION: In well-defined electroclinical syndromes, qualitative IED morphology appears to provide additional prognostic information regarding early ASM response. These findings suggest that EEG morphology may complement syndrome-based assessment and that variability in spike and sharp-wave morphology may reflect underlying electrophysiological heterogeneity extending beyond fixed syndrome la...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.