Epilepsy News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Using Seizure-Risk Forecasts to ID Best Time for Epilepsy Monitoring - NASHVILLE, Tennessee ― Scheduling video-electroencephalography (vEEG) monitoring on the basis of personalized seizure risk forecasts may improve diagnostic accuracy, emerging research suggests. In a ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

What Is Neurofeedback Therapy And How Does It Work? - Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...

Novel neurofeedback technique enhances awareness of mind-wandering - Everyone knows the feeling. You are trying to concentrate on driving or studying, or paying attention in a boring meeting, but suddenly, you realize that you are thinking about something irrelevant to ...

What Does a Neurofeedback Technician Do? - Neurofeedback is about helping a client's brain learn to self-regulate by showing it its own EEG activity on a screen or through headphones. It is like going to the gym for your brain. It is not a ...

Neurofeedback for ADHD: Significant, Lasting Improvement - Computer-based neurofeedback can produce significant and lasting improvement in attention and focus in children with attention-deficit/hyperactivity disorder (ADHD ...

Benefits of neurofeedback for those with ADHD mainly due to unexpected factors - The most common form of neurofeedback for ADHD has been training down the theta-waves and training up beta-waves. Our study is the first large, well-blinded study of theta-beta neurofeedback designed ...

Phenotype-driven response to sodium channel blockers in neonatal and infantile genetic epilepsies with tonic seizures - CONCLUSION: SCBs are safe and highly effective in early-onset genetic epilepsies with tonic seizures, particularly in self-limited phenotypes. Recognition of tonic seizure semiology may guide early, phenotype-driven treatment decisions while awaiting genetic results.

How far-reaching is the impact of temporal lobe epilepsy surgery on quality of life 10-44 years after the operation? - CONCLUSION: Many years after surgery, most patients report good QoL. While seizure freedom remains central, factors linked to cognitive compensation and reduced stress, including disability pension, appear increasingly relevant. Changing expectations may also contribute to improved QoL. Overall, patients appear well adapted post-surgery, with a reduced long-term impact of epilepsy and surgery.

Caring Across Languages: Clinician Perceptions of Variability in US Pediatric Outpatient Epilepsy Care - Little is known about outpatient language access practices in the United States for children with epilepsy whose families use languages other than English (LOE) for medical care. The Pediatric Epilepsy Research Consortium (PERC) aimed to characterize clinician perceptions of institutional practices by developing and conducting a descriptive survey. We weighted statistical outcomes to equally re...

SVHRSP Attenuates PTZ-Induced Seizure-Like Behavior in C. elegans: Involvement of HSF-1 and Associated Changes in GABAergic Markers and Mitochondrial Homeostasis - Epilepsy is a prevalent neurological disorder. Nevertheless, approximately one-third of patients fail to achieve sufficient seizure control through current pharmacological treatments. This unmet need underscores the importance of developing new antiseizure treatments for drug-resistant epilepsy. Scorpion venom heat-resistant synthetic peptide (SVHRSP), which is derived from scorpion venom and c...

Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits - Developmental delay and seizures with or without movement abnormalities (OMIM 617836) caused by heterozygous pathogenic variants in the DHDDS gene (DHDDS-CDG) is a rare genetic disease that belongs to the progressive encephalopathy spectrum. It results in cognitive delay in affected children, accompanied by myoclonus, seizures, ataxia and tremor, which worsens over time. DHDDS encodes a subunit...

Genetic landscape of pediatric seizures in Southeast China: identification of a novel GLI3 frameshift variant through whole-exome sequencing - CONCLUSION: Whole-exome sequencing identified clinically relevant genetic findings in a subset of Southeast Chinese children with seizure disorders. The novel GLI3 frameshift variant may suggest an expansion of the GLI3-associated phenotypic spectrum, but further segregation, functional validation, and larger cohort studies are needed. The high proportion of variants of uncertain significance h...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.