Epilepsy and Seizure News
First seizure clinic speeds time to diagnosis with pediatric epilepsy -
Children referred to a first seizure clinic (FSC) see a neurologist epilepsy specialist within one week, according to a study presented at the annual meeting of the American Epilepsy Society, held ...
GLP-1s Linked to Better Seizure Control in Epilepsy -
GLP-1s are linked to lower seizure recurrence, hospitalization, and mortality risk than other glucose-lowering drugs in adults with epilepsy, new research shows.
Xenon Showcases New 48-Month Azetukalner OLE Study Data in Epilepsy at AES 2025 -
Monthly reductions in seizure frequency of 90.9% among participants treated for ≥48 months in the OLE, with 38% achieving ≥1 year of seizure ...
Praxis claims efficacy success in phase 2 seizure trial, setting up approval talks with FDA -
“SCN2A and SCN8A DEEs are devastating conditions with extremely high mortality due to the debilitating seizure burden they impose on patients, and there are currently no approved treatment options,” ...
NeuroVice Announces PATI Now Available, Launches First FDA-Cleared Device Designed for Seizure Oral Injury Protection and Airway Management at American Epilepsy Society Annual ... -
Today, NeuroVice announced that PATI is now commercially available, marking a breakthrough moment for millions of patients living with focal and grand-mal seizures. The company will debut the ...
OHSU epilepsy patient nearly seizure-free after regenerative brain cell therapy procedure -
PORTLAND, Ore. — Oregon Health and Science University is at the forefront, again, of a possible life-changing medical advancement. “I think this is a turning point. This is where I’m hopeful that ...
Stoke, Biogen present zorevunersen data at American Epilepsy Society -
Stoke Therapeutics (STOK) and Biogen (BIIB) announced data presentations on zorevunersen, an investigational antisense oligonucleotide, as a ...
Epilepsy awareness in the workplace: training and safety tips -
More than 35,000 Long Islanders live with epilepsy. Experts urge businesses to provide seizure training, safety plans, and awareness to protect employees and customers.
NEURELIS TO PRESENT CLINICAL DATA AT AMERICAN EPILEPSY SOCIETY ANNUAL MEETING -
Neurelis, Inc., the innovator behind VALTOCO® (diazepam nasal spray), today announced it will participate in the American Epilepsy Society (AES) Annual Meeting December 5-9, 2025 in Atlanta. The ...
Health Beat: Treating epilepsy -
Nearly three million Americans live with epilepsy. And for one-third of them, anti-seizure medications don't work.
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Multiscale network perspectives on glioma: from tumour biology to symptoms, survival and treatment -
Adult glioma is associated with a wide range of symptoms and variable survival that are not fully explained by tumour location or subtype. Recent work suggests that the disease may be better understood using a network-based framework, as opposed to more traditional localizationist thinking. In this Review, we describe three major types of network scaffolds relevant in people with glioma: sympto...
Lightweight Seizure Prediction Model based on Kernel-Enhanced Global Temporal Attention -
Clinically, epilepsy manifests as a chronic condition marked by unprovoked, recurrent seizures, plaguing over 70 million individuals with debilitating seizures and life-threatening complications. Approximately 30% of patients with epilepsy do not respond to conventional antiepileptic drugs, indicating the limited efficacy of these medications in controlling seizures universally. Therefore, seiz...
The neuro-cardiac axis in epilepsy -
Epilepsy is a major noncommunicable neurological disorder, most prevalent among patients with cardiovascular (CV) disease (CVD). Epilepsy incurs a higher risk for developing CVD with an odds ratio of 2.25. CVDs can influence the function of the brain, and many brain diseases are linked with CV dysfunction, in a resiprocal relationship (neurocardiac axis). In patients with epilepsy, interactions...
Use of new approach methodologies (NAMs) in epilepsy research and seizure risk assessment -
Seizures are the hallmark of treatment-resistant epilepsy and are also a frequent adverse event in drug safety testing. Here we present a critical evaluation of new approach methodologies (NAMs) in epilepsy research and seizure liability. Specifically, recent data have shown that seizure can be profiled using an in vitro seizure liability assay (iSLA) comprising a microelectrode array (MEA) of ...
Efficacy, safety, and predictors of vagus nerve stimulation in children with drug-resistant epilepsy: A single-center prospective study -
CONCLUSION: VNS is an effective and safe long-term therapy for pediatric DRE, with cumulative benefits over time. The presence of absence seizures and abnormal neuroimaging findings were key predictors of a less favorable response, which may inform clinical decision-making regarding patient selection. Caution is advised when initiating VNS therapy in children with DRE exhibiting these character...
Intraoperative electrocorticography in awake brain surgery: comparing three electrode configurations for detecting stimulus-induced and spontaneous epileptiform activity -
CONCLUSIONS: This study demonstrates a higher rate of detection of epileptiform activity with circular and standard grids when compared with strip electrodes. The standard HD grid was used less during electrical stimulation, demonstrating the importance of both the number of contacts and design array when considering optimal conditions for ECoG and functional brain mapping.
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