Epilepsy News

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

EPILEPSY AWARENESS: Local neurologist explains condition & seizure first aid - COLUMBUS, Ga. (WRBL) — Local experts say epilepsy is not a condition to be afraid of. Piedmont Columbus Regional pediatric neurologist Pierre Fequiere treats patients with epilepsy every day and knows ...

Understanding epilepsy: Seven ways to respond to an epileptic seizure - At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

Microbiota-gut-brain axis and treatment resistance in epilepsy: a multicentre prospective study protocol (CARE) - INTRODUCTION: Approximately one-third of people with epilepsy (PWE) experience resistance to treatment, including pharmacological therapies, epilepsy surgery, vagus nerve stimulation (VNS) and dietary interventions such as the ketogenic diet (KD). Emerging evidence suggests that the gut microbiota may influence seizure susceptibility and treatment response through the microbiota-gut-brain axis,...

Ketogenic diet in children with epilepsy: A bibliometric and science mapping analysis of global research - CONCLUSION: The field of ketogenic diet research in childhood epilepsy has evolved into a clinically focused and increasingly multidisciplinary area. While seizure control remains central, emerging themes emphasize individualized treatment, long-term safety, and evidence-based standardization. This study clarifies research dynamics, intellectual frameworks, and knowledge gaps, providing a frame...

Seize the Data: A User-Friendly GUI for High-Resolution Analysis of Seizure Dynamics in HD-MEA Recordings - High-density multielectrode arrays (HD-MEAs) generate large, complex datasets that are challenging to efficiently manage and analyze with existing tools, especially in open-source environments. To address this, we developed the BYU Seizure and Analytics Tool (YSA), an open-source graphical user interface built in Python and C++ for efficient analysis and visualization of HD-MEA recordings. The ...

Synaptic dysfunction-related gene expression spatially correlates with widespread cortical network atrophy in temporal lobe epilepsy - Temporal lobe epilepsy (TLE) exhibits marked lateralized gray matter alterations, yet whole-brain network vulnerability patterns, particularly those independent of seizure laterality, remain incompletely understood. Furthermore, the spatial correspondence between macroscopic network disruptions and underlying molecular architectures lacks systematic characterization, limiting mechanistic insigh...

Interictal thalamocortical network configuration is associated with susceptibility to seizure-related impaired consciousness in focal epilepsy - CONCLUSIONS: Interictal thalamocortical network organization involving the CMN is associated with susceptibility to seizure-related impaired consciousness. Band-specific differences in the relative configuration of CMN-SOZ and CMN-non-SOZ synchronization, together with reduced aperiodic offset in FBTCS, may reflect interictal network states related to vulnerability or resilience to impaired con...

Transcranial acoustoelectric imaging (tABI) of seizure activity in human head model with neuronavigation - The human brain consists of multiple interacting neuronal networks that interleave at fine spatial and temporal scales. This complexity presents a challenge for scalp EEG and other noninvasive mapping techniques to accurately identify seizures and abnormal current patterns from background activity. To address this unmet need, this study investigates Transcranial Acoustoelectric Brain Imaging (t...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.