Epilepsy News

Recent news about epilepsy, seizures and treatments.

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Epilepsy and Seizure News

Experts warn TikTok epilepsy care videos can be misleading - Fake clickbait TikTok videos about epilepsy treatments are receiving more views than accurate, evidence-based offerings, a new study says.

Promising Long-Term Results for Novel Antiseizure Medication for Resistant Epilepsy - A novel Kv7 potassium channel opener, may offer a unique treatment option for patients with resistant focal onset seizures.

Unified EEG imaging improves mapping for epilepsy surgery - A new advance from Carnegie Mellon University researchers could reshape how clinicians identify the brain regions responsible for drug-resistant epilepsy. Surgery can be a life-changing option for ...

Praxis claims efficacy success in phase 2 seizure trial, setting up approval talks with FDA - “SCN2A and SCN8A DEEs are devastating conditions with extremely high mortality due to the debilitating seizure burden they impose on patients, and there are currently no approved treatment options,” ...

GLP-1s Linked to Better Seizure Control in Epilepsy - GLP-1s are linked to lower seizure recurrence, hospitalization, and mortality risk than other glucose-lowering drugs in adults with epilepsy, new research shows.

Nerve Stimulation for Epilepsy: Intracranial Versus Extracranial Approaches Compared - But long-term mortality -- which her group considered a proxy for seizure control -- became substantially worse for patients treated with VNS compared with the intracranial implants, starting at about ...

Epilepsy awareness in the workplace: training and safety tips - More than 35,000 Long Islanders live with epilepsy. Experts urge businesses to provide seizure training, safety plans, and awareness to protect employees and customers.

Health Beat: Treating epilepsy - Nearly three million Americans live with epilepsy. And for one-third of them, anti-seizure medications don't work.

Teen seizure-free after two brain surgeries, returns to cheer team - Kaylee Hill, diagnosed with epilepsy before high school, is now seizure-free after advanced mapping technology guided two successful surgeries.

First seizure clinic speeds time to diagnosis with pediatric epilepsy - Children referred to a first seizure clinic (FSC) see a neurologist epilepsy specialist within one week, according to a study presented at the annual meeting of the American Epilepsy Society, held ...

Medical News Today

PubMed

Mapping epileptogenic brain using a unified spatial-temporal-spectral source imaging framework - Noninvasive electrophysiological source imaging (ESI) is a valuable tool for localizing and imaging brain activity, with significant potential to aid presurgical planning in focal drug-resistant epilepsy (fDRE) patients. Scalp electroencephalography (EEG) biomarkers, including interictal spikes, high-frequency oscillations (HFOs), and seizures, each offer unique capabilities in estimating the e...

Fourth ventricular hamartoma presenting with epileptic spasms: case-based review and surgical considerations - CONCLUSION: Early recognition of FVRHs as potential epileptogenic foci and timely surgical intervention can lead to seizure freedom and favorable neurodevelopmental outcomes. This case reinforces the role of cerebellar lesions in pediatric epilepsy and supports aggressive surgical management when feasible.

Metformin Alleviates Cognitive Impairment in Chronic-Phase Epileptic Rats by Modulating the TLR4/MyD88/NF-κB Pathway and Gut Flora Composition - Epilepsy (EP) is characterized by recurring spontaneous seizures, often leading to long-standing cognitive impairment, significantly impacting the quality of life. Due to the unknown pathogenic pathways, developing effective treatments for epilepsy-associated cognitive impairment has been challenging. Metformin, a first-line oral antidiabetic drug, has proven effective in various EP models. Rec...

Meta-analysis of genetic mapping studies in mice reveals candidate epilepsy modifier genes that are outside the current drug development landscape - OBJECTIVE: Despite decades of development in anti-seizure medications, ~30% of individuals remain refractory to all treatments, and none of the existing therapies are disease modifying. Identifying targets outside the current preclinical paradigm is critically important. This study aimed to characterize the landscape of current epilepsy treatments at the level of gene interaction networks and i...

Individual-specific resting-state networks predict language dominance in drug-resistant epilepsy - CONCLUSIONS AND RELEVANCE: Our model is publicly available (github link), which may be used to predict language dominance from approximately 10 minutes of resting-state fMRI. This provides a practical, non-invasive tool for presurgical evaluation of drug-resistant epilepsy.

Case Report: Congenital neurosyphilis presenting as post-hemorrhagic hydrocephalus in a preterm infant and a review of literature - CONCLUSION: This case highlights the relevance of universal maternal syphilis screening and early neonatal evaluation. Maternal Treponema pallidum infection during pregnancy can result in preterm birth and may be associated with neurological complications, such as hemorrhages, seizures, and motor impairment, which can require multidisciplinary management and long-term follow-up.

Science Daily

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.

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