Epilepsy News
Recent news about epilepsy, seizures and treatments.
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New fMRI neurofeedback study trains the brain to reduce depressive rumination -
Major Depressive Disorder (MDD) is far from a cookie-cutter diagnosis. Different patients report suffering from different subsets of symptoms, yet most are ultimately prescribed the same first-line ...
Rewiring Your Brain: Neurofeedback Goes Mainstream - See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Will Strahl walked up to my door with a massive black briefcase in his ...
Neurofeedback Trains Brain to Stop Depressive Rumination - A new study uses real-time fMRI neurofeedback to help depression patients reduce rumination by training specific brain circuits in a gamified environment.
What Is Neurofeedback Therapy And How Does It Work? - Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...
Neurofeedback gets you back in the zone - Researchers have shown -- for the first time -- that they can use online neurofeedback to modify an individual's arousal state to improve performance in a demanding sensory motor task, such as flying ...
Rewiring Your Brain: Neurofeedback Goes Mainstream - See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Will Strahl walked up to my door with a massive black briefcase in his ...
Neurofeedback Trains Brain to Stop Depressive Rumination - A new study uses real-time fMRI neurofeedback to help depression patients reduce rumination by training specific brain circuits in a gamified environment.
What Is Neurofeedback Therapy And How Does It Work? - Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...
Neurofeedback gets you back in the zone - Researchers have shown -- for the first time -- that they can use online neurofeedback to modify an individual's arousal state to improve performance in a demanding sensory motor task, such as flying ...
Medical News Today
PubMed
Neuroimaging spectrum of GATOR1-related epilepsy (GATORopathies) -
CONCLUSION: GATOR1-related epilepsy demonstrates substantial variability in neuroimaging and electroclinical features, extending beyond focal cortical malformations to include diffuse cortical malformations, generalized neuroparenchymal atrophy, and MRI-negative presentations. These findings highlight the value of integrated genetic, imaging, and electroclinical assessment in routine clinical p...
Comparative Predictive Performance of Serum and Dose-Normalized Valproate Levels for Seizure Control in Adults With Epilepsy - Background Valproate is a widely used antiepileptic drug, but its clinical response shows considerable interindividual variability. Conventional therapeutic ranges may not reliably predict seizure control, and the role of dose-normalized valproate levels in forecasting seizure as an outcome remains unclear. Objective To evaluate the predictive performance of serum valproate levels for seizure c...
Clinical application of HMGB1-TLR4 signaling pathway-mediated neuroinflammatory markers in infantile epileptic spasms syndrome - CONCLUSIONS: The HMGB1-TLR4 pathway mediates neuroinflammation in IESS pathogenesis and may serve as a therapeutic target. A high Δ(Pre-Post) HMGB1 level was identified as a protective factor against short-term treatment failure of prednisone, indicating that dynamic monitoring of HMGB1 has clinical value for predicting short-term treatment responses to prednisone, though it does not predict lo...
Altered white matter structural network in self-limited epilepsy with centrotemporal spikes - CONCLUSIONS: SeLECTS presents with topological changes, which were associated with duration of epilepsy and neuropsychological score, and WM structural network might help clinical classification for children with SeLECTS. The STG.L may might be a suitable brain area for monitoring the disease condition.
Incidental Dysembryoplastic Neuroepithelial Tumor Identified During the Evaluation of Acute Headache and Vomiting in a Pediatric Patient - Acute headache in pediatric patients often warrants neuroimaging when accompanied by vomiting or concerning clinical features. While most cases are benign or infectious in etiology, incidental structural abnormalities may be discovered. Dysembryoplastic neuroepithelial tumors (DNETs) are rare, benign, WHO grade I glioneuronal tumors, commonly associated with epilepsy and typically located in co...
Refractory seizures as a manifestation of anti-epileptic drug induced hypocalcemia and vitamin D deficiency - Enzyme-inducing antiepileptic drugs (EIAEDs) such as carbamazepine, phenytoin, phenobarbital, and primidone are used in the management of epilepsy and can alter hepatic enzymes of the cytochrome P450 (CYP450) system. This can have a significant impact on vitamin D metabolism. We describe the case of a 34-year-old female diagnosed with focal epilepsy who presented to the hospital at 25-weeks ges...
Comparative Predictive Performance of Serum and Dose-Normalized Valproate Levels for Seizure Control in Adults With Epilepsy - Background Valproate is a widely used antiepileptic drug, but its clinical response shows considerable interindividual variability. Conventional therapeutic ranges may not reliably predict seizure control, and the role of dose-normalized valproate levels in forecasting seizure as an outcome remains unclear. Objective To evaluate the predictive performance of serum valproate levels for seizure c...
Clinical application of HMGB1-TLR4 signaling pathway-mediated neuroinflammatory markers in infantile epileptic spasms syndrome - CONCLUSIONS: The HMGB1-TLR4 pathway mediates neuroinflammation in IESS pathogenesis and may serve as a therapeutic target. A high Δ(Pre-Post) HMGB1 level was identified as a protective factor against short-term treatment failure of prednisone, indicating that dynamic monitoring of HMGB1 has clinical value for predicting short-term treatment responses to prednisone, though it does not predict lo...
Altered white matter structural network in self-limited epilepsy with centrotemporal spikes - CONCLUSIONS: SeLECTS presents with topological changes, which were associated with duration of epilepsy and neuropsychological score, and WM structural network might help clinical classification for children with SeLECTS. The STG.L may might be a suitable brain area for monitoring the disease condition.
Incidental Dysembryoplastic Neuroepithelial Tumor Identified During the Evaluation of Acute Headache and Vomiting in a Pediatric Patient - Acute headache in pediatric patients often warrants neuroimaging when accompanied by vomiting or concerning clinical features. While most cases are benign or infectious in etiology, incidental structural abnormalities may be discovered. Dysembryoplastic neuroepithelial tumors (DNETs) are rare, benign, WHO grade I glioneuronal tumors, commonly associated with epilepsy and typically located in co...
Refractory seizures as a manifestation of anti-epileptic drug induced hypocalcemia and vitamin D deficiency - Enzyme-inducing antiepileptic drugs (EIAEDs) such as carbamazepine, phenytoin, phenobarbital, and primidone are used in the management of epilepsy and can alter hepatic enzymes of the cytochrome P450 (CYP450) system. This can have a significant impact on vitamin D metabolism. We describe the case of a 34-year-old female diagnosed with focal epilepsy who presented to the hospital at 25-weeks ges...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.