Epilepsy News

Measuring transition success from paediatric to adult epilepsy services and its association with seizure outcomes: a UK retrospective cohort study - CONCLUSIONS: A novel transition success tool was developed. Larger, multicentre studies are needed to validate this tool and confirm associations with long-term outcomes.

A retrospective analysis of perinatal stroke: hemostasis abnormalities, neonatal seizures, epilepsy recurrence, and two-year neurological outcome - BACKGROUND: Neonatal stroke is a rare but potentially severe condition that may lead to long-term neurological impairment. Several factors may influence both its occurrence and outcomes.

Feline Hippocampal Necrosis and Temporal Lobe Epilepsy: A review of current literature and definitions - Feline Hippocampal Necrosis (FHN) is a histopathological diagnosis first identified 25 years ago in domestic cats, and characterised by marked neuronal necrosis largely restricted to the hippocampus. FHN is often conflated with an overlapping condition, Hippocampal Sclerosis (HS). FHN does not represent a singular neurological condition, but rather a common endpoint of several disease entities ...

Reporting Quality and Evidence Support in Randomized Controlled Trials of Bupleurum-Based Herbal Medicine Formulas for Epilepsy - CONCLUSIONS: Bupleurum-based herbal formulas demonstrate clinically significant benefits in reducing seizure frequency and duration while improving overall treatment response. However, the evidence is undermined by poor reporting quality and methodological flaws. Future trials must rigorously adhere to the CONSORT and CONSORT-CHM guidelines to enhance the validity and translational potential of...

The minimally invasive grid approach for seizure localization: patient series - BACKGROUND: Epilepsy surgery continues to advance new minimally invasive techniques for both seizure localization and treatment. Stereo-electroencephalography (sEEG) is increasingly being used; however, some patients continue to require subdural electrodes for neocortical mapping. Traditional subdural grid electrodes involve medium to large craniotomies, relatively large incisions, and can be a...

Typical and Atypical Frequency-Based Subtypes of EEG Reactivity in Hospitalized Patients and Association With Comorbidities and Outcomes - BACKGROUND AND OBJECTIVES: EEG reactivity (EEG-R) is currently classified as present, absent, or stimulus-induced rhythmic, periodic, or ictal discharges, per the American Clinical Neurophysiology Society's 2021 Critical Care EEG Terminology. However, our previous study suggested that there may be other forms of EEG-R that warrant distinction, potentially associated with different comorbidities...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.