Epilepsy and Seizure News
Pediatrics in Brevard: Here's what to know about epilepsy, what to do if someone has seizure -
More than 3.4 million people in the United States have epilepsy, so it is a relatively common diagnosis. In fact, it is the fourth-most common neurologic condition in the world. November is National ...
Understanding epilepsy: Seven ways to respond to an epileptic seizure -
At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...
Proposed bill aims to improve seizure response awareness in state workplaces -
Advocates say bystanders often do the wrong thing without realizing, sometimes operating off of common misconceptions about how to help.
Why Early Detection of Seizures and Epilepsy Is so Important -
For parents, a child having a seizure is one of the most frightening experiences imaginable. While many childhood seizures are brief and isolated, others are more serious and persistent. To make the ...
Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time -
Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...
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Uncovering targets and molecular pathways for personalizing treatment in epilepsy -
INTRODUCTION: Despite licensing of many new antiseizure drugs over the last few decades, the proportion of pharmacoresistant epileptic seizures has remained largely unchanged at about 30%. However, recent progress in genetics has revealed new and more specific therapeutic targets that can be addressed through improved drug design and advancements in gene therapy, such as improved antisense olig...
Automatic EEG artifact detection using a local-global feature fusion network in time and time-frequency domains -
CONCLUSIONS: The method effectively exploits the complementarity among the three feature types by utilizing feature concatenation and CNN-based fusion, enhancing feature representation and improving model generalization.
Identification and validation of key genes as diagnostic biomarkers for epilepsy using bioinformatics and machine learning -
Epilepsy is a common neurological disorder with a complex molecular pathogenesis. Approximately one-third of patients experience drug-resistant seizures, which severely impairs their quality of life. This study employed an integrated bioinformatics and machine learning approach to identify key genes associated with epilepsy. Epilepsy-related datasets from the GEO database were analyzed using di...
Shared metabolic pathways in epilepsy and plant immunity: From evolution to diet -
Epilepsy is a widespread neurological disorder characterized by recurrent seizures resulting from abnormal electrical activity in the brain. The origin and severity of these seizures vary depending on the brain regions involved. A key factor influencing seizure susceptibility is vitamin B6, an essential cofactor in neurotransmitter metabolism, where both deficiency and excess can lead to advers...
A model of new-onset refractory status epilepticus (NORSE) using intrahippocampal kainic acid in adolescent mice -
New-onset refractory status epilepticus (NORSE) is a devastating neurological condition characterized by the sudden onset of prolonged, drug-resistant seizures in previously healthy individuals. A clinically relevant animal model is essential to elucidate its pathophysiology, improve treatment, and reduce morbidity and mortality in NORSE. We developed an adolescent mouse model of NORSE by induc...
Impact of pediatric epilepsy on sleep architecture: A systematic review and meta-analysis -
CONCLUSION: Pediatric epilepsy is significantly associated with multidimensional sleep architecture abnormalities, including increased sleep disturbances, reduced sleep efficiency, and decreased REM sleep proportion. This study highlights the need to integrate sleep assessment and management into comprehensive epilepsy care, providing a data-supported basis for optimizing clinical outcomes.
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