Epilepsy News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Patients engage with epilepsy monitor in real time, improving seizure detection - A team has built an AI-based interface that enables real-time communication between patients and epilepsy monitoring devices. As part of a small clinical study at the University of Pennsylvania in ...

Seizure action plans: More than management tools for epilepsy - Newswise — Historically, seizure action plans have focused on certain high-risk groups — such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters ...

Seizure or epilepsy? Understanding the critical difference could save lives - A sudden episode of shaking, confusion, or loss of awareness can be frightening - but does it mean epilepsy? Understanding the difference between a seizure and epilepsy is crucial for timely treatment ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

Efficacy of Lactobacillus reuteri as an adjunctive therapy for seizure control and quality of life in pediatric drug-resistant epilepsy: A prospective interventional study - CONCLUSIONS: In this single-arm before-after study, statistically significant within-participant changes in HRQOL and seizure frequency were observed during the 12-week period following adjunctive L. reuteri supplementation. However, the absolute magnitude of these changes was modest and their clinical significance remains uncertain. Because there was no concurrent placebo control group, the ob...

Combining responsive neurostimulation with resection or ablation for treatment of epilepsy: a multicenter experience - CONCLUSIONS: Combined RNS with resection or ablation might provide meaningful seizure control in complex drug-resistant epilepsy with acceptable safety profiles. These findings describe current practice and support further investigation of hybrid surgical strategies in patients with challenging seizure networks as a potential treatment strategy.

More Than a Daughter: Margaret A. Lennox-Buchthal (1913-2001), Epileptologist - In a 2010 book chapter on the pioneering encephalographer Mary A.B. Brazier, PhD (1904-1995), a photo of a smiling woman is labeled "Margaret Lennox-Buchthal, wife of Fritz, daughter of William Lennox." Yet, like most women, Margaret Lennox-Buchthal, MD (1913-2001), was more than a wife and a daughter. She was an assistant professor at the Yale School of Medicine and associate professor at the ...

AI for Poststroke Epilepsy: Scoping Review of Imaging-Based Prediction Models and Implications for African Settings - CONCLUSIONS: Imaging-based AI for predicting PSS and PSE has progressed rapidly, but important methodological and geographical gaps remain. Limited external validation, heterogeneous reporting, and the absence of African development and validation cohorts restrict confidence in the generalizability of existing models. Future research should prioritize the development of explainable imaging-base...

Routing to the seizure in postoperative human glioma cortex: spatio-temporal uncoupling between slow and fast extracellular neuronal activities - CONCLUSIONS: In the periglioma human cortex, seizures arise from progressively recruited neuronal assemblies sculpted together with HFOs, providing new insights into the microphysiological processes of glioma-related ictogenesis and requiring consideration of the preictal fast and focal neuronal activity.

A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy - CONCLUSION: The present study can expand the mutational spectrum of CDKL5 and highlight the clinical advantage of sequencing-based genetic testing for early diagnosis and personalized therapeutic management of refractory epilepsy.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.