Epilepsy News

Fenfluramine linked to significantly improved seizure outcomes vs. placebo at 14 weeks - Individuals with a rare form of epilepsy treated with fenfluramine experienced significantly greater seizure reduction as well as clinically meaningful global functioning improvement compared with ...

What to know about epilepsy and seizure first aid - November is Epilepsy Awareness Month. Many people may already be aware of the condition from its prevalence in medical dramas, but that portrayal is often exaggerated and does not fully encapsulate ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - The first seizure clinic model enabled rapid diagnosis and treatment for children with epilepsy, according to data presented at the American Epilepsy Society Annual Meeting. These specialized ...

Many people have seizures. Here's why it doesn’t always mean epilepsy - One of the most common causes of epilepsy is a structural brain abnormality. “Epilepsy can result from structural issues in the brain, such as brain tumors, brain injuries, brain infections or ...

AAN’s First-Ever Functional Seizure Guideline Released - The AAN’s first-ever functional seizure guideline targets stigma and unnecessary treatment, offering clearer diagnostic steps and guidance on effective psychological interventions.

New tools map seizures in the brain, improve epilepsy treatment - Two new models could solve a problem that's long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part ...

What Is Epilepsy Surgery? - Medications can control seizures in most people with epilepsy, but they don’t work for everyone. About 30% of people taking the drugs can’t tolerate the side effects. In some cases, brain surgery may ...

Want good info on epilepsy treatment? Don't ask Dr. TikTok - ATLANTA -- Much of the content on social media regarding epilepsy treatment isn't accurate and could actually hurt people, researchers reported at the American Epilepsy Society (AES) annual meeting.

Ozempic Linked to Smaller Risk of Epilepsy - Taking GLP-1 medications like Ozempic is linked to a smaller risk of developing epilepsy than taking DPP-4 inhibitors. | Drug Discovery And Development ...

Autism and Epilepsy: What to Know If You’re on the Spectrum and Have Seizures - Autism spectrum and epilepsy frequently occur together. Both conditions affect brain function and behaviors. However, researchers do not yet fully understand why the two conditions share such a strong ...

Rewiring Your Brain: Neurofeedback Goes Mainstream - Will Strahl walked up to my door with a massive black briefcase in his hand, the kind you could use to tote a dirty bomb. Once inside my living room, he cracked open the case and removed a laptop, a ...

What is neurofeedback therapy? - Medically reviewed by Shaheen Lakhan, MD, PhD, FAAN Key Takeaways Neurofeedback therapy uses electrical sensors on the head to track brain reactions.The therapy helps with conditions like ADHD, ...

How Neurofeedback Can Help You - Neurofeedback is a computer-guided, noninvasive brain-function training based on EEG feedback. Neurofeedback is also called “neurotherapy,” “neurobiofeedback,” or “electroencephalography” (EEG) ...

Novel adjunct treatments for posttraumatic stress disorder: Neurofeedback and deep brain reorienting - Dr. Lanius discusses the need for novel adjunct treatments for posttraumatic stress disorder (PTSD), highlighting two promising approaches ...

What Is Neurofeedback Therapy And How Does It Work? - Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...

Comparative study of behavior and pathology in three mouse models of kainic acid-induced epilepsy - CONCLUSION: The intravenous + kainic acid model exhibited low mortality, reduced dosage requirements, and inducible localized pathological damage, rendering it suitable for investigating localized neuronal injury. The intraperitoneal method, though simple with higher mortality, is preferable for systemic seizure models. The noninvasive intranasal approach is promising for trauma-sensitive resea...

Intranasal Seletracetam in a Patient with Reading Epilepsy: First-in-Human Use to Prevent Reflex Seizures - We report the first human use of intranasal seletracetam (SEL) to prevent reflex seizures. A patient with epilepsy with reading-induced seizures on levetiracetam (3,000 mg/day) continued to experience reading-induced focal seizures with preserved consciousness. Detectable in serum within 2 minutes of intranasal administration, 30 mg seletracetam delayed seizure onset from 1:56 (placebo) to 4:17...

Probiotics in epilepsy treatment: a meta-analysis of efficacy and safety - CONCLUSION: Probiotics improved seizure activity, relative power in certain EEG frequency bands, and intestinal barrier function without increasing the incidence of adverse reactions, supporting their feasibility as complementary treatment for epilepsy. Limited sample size and methodological necessitate further validation.

A Narrative Review of Emerging Immune Targets in Neuroinflammation-Driven Epileptogenesis: From Complement Pathways to Immune Checkpoints - Epileptogenesis, the process by which a normal brain becomes epileptic, has long been attributed to excitotoxicity and neuronal hyperexcitability. Advances in neuroimmunology now indicate that neuroinflammation contributes materially to seizure initiation, propagation, and chronicity, opening avenues for therapies that aim to modify disease biology rather than merely suppress symptoms. To maint...

Shaking in Darkness: Posterior Reversible Encephalopathy Syndrome (PRES)-Induced Acute Bilateral Blindness and Seizures - Posterior reversible encephalopathy syndrome (PRES) is a neurologic disorder that causes acute or subacute cerebral edema, brain capillary leakage, and a hyperperfusion encephalopathy that results in presenting symptoms of headache, vision changes, seizure activity, altered mentation, nausea or vomiting, or focal neurologic deficits. We describe a case of PRES in the setting of severe hypertens...

Clinical Utility of Whole-Exome Sequencing in a Consanguineous Family with UNC80-related Neurodevelopmental Disorder: A Case Series and Review of the Literature - The UNC79 and UNC80 proteins form key regulatory subunits of the sodium leak channel, non-selective (NALCN), a channel fundamental to maintaining neuronal excitability. The UNC80 gene, located on chromosome 2 at the 2q34 locus, encodes a critical component of this channel complex, contributing to its permeability to Na⁺, K⁺, and Ca²⁺ ions. Mutations in this gene are presumed to be linked to sym...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.