Epilepsy News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Study: Epilepsy patients benefit from structured 'seizure action plans' - A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status. These ...

Using Seizure-Risk Forecasts to ID Best Time for Epilepsy Monitoring - NASHVILLE, Tennessee ― Scheduling video-electroencephalography (vEEG) monitoring on the basis of personalized seizure risk forecasts may improve diagnostic accuracy, emerging research suggests. In a ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Pediatrics in Brevard: Here's what to know about epilepsy, what to do if someone has seizure - Add Yahoo as a preferred source to see more of our stories on Google. More than 3.4 million people in the United States have epilepsy, so it is a relatively common diagnosis. In fact, it is the fourth ...

In people with epilepsy, sleeping after a seizure may trigger more seizures - Add Yahoo as a preferred source to see more of our stories on Google. A new study suggests that the memory-forming stage of sleep could be key for understanding epileptic seizures. . | Credit: ...

A Young Child With Global Developmental Delay and Epilepsy Secondary to a Novel Variant of KBG Syndrome - KBG syndrome is a rare neurodevelopmental disorder caused by changes in the ANKRD11 gene (ankyrin repeat domain-containing protein 11). It is typically inherited in an autosomal dominant pattern. This syndrome is characterized by a distinct constellation of clinical findings, including short stature, distinctive craniofacial manifestations, skeletal abnormalities, and abnormal patterns of hair ...

Neuromodulation by electrical stimulation timing during picture naming task based on high gamma dynamics - CONCLUSIONS: A strong relationship exists between the HGA and the ECS-timing. Short ECS disrupts brain functions and networks when appropriately aligned with the HGA. Combining HGA dynamics with ECS reveals the functional distribution and physiological dynamics during naming tasks.

Machine learning-based lateralization and localization of seizure onset in focal cortical dysplasia patients using ictal scalp EEG - INRODUCTION: This study aimed to develop and evaluate a machine learning framework for classifying seizure onset zone lateralization and localization in patients with focal cortical dysplasia using ictal scalp electroencephalography (EEG).

Dynamic alterations in cardiac autonomic regulation during recurrent generalized seizures - Epileptic seizures are associated with cardiovascular disturbances, yet how cardiac autonomic regulation changes across repeated seizures remains unclear. Here, using a pentylenetetrazol-induced murine model, we combined ECG telemetry, heart rate variability (HRV) analysis, pharmacological intervention, optical mapping, and brainstem patch-clamp recordings to characterize seizure-associated aut...

Adaptive immune dysregulation drives new-onset refractory status epilepticus - New-onset refractory status epilepticus (NORSE) is a life-threatening neurological condition that emerges abruptly in individuals without a prior history of epilepsy and is characterised by seizures that are refractory to standard antiseizure medications. NORSE is associated with high mortality and long-term neurological deficits, and autoimmune encephalitis (AIE) represents a major identifiabl...

Antenatal diagnosis and maternal sirolimus treatment of polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome - BACKGROUND: Polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome is a rare autosomal recessive mTORopathy caused by biallelic STE20-related kinase adaptor alpha (STRADA) loss-of-function variants. Animal models demonstrate that in utero mechanistic target of rapamycin (mTOR) inhibition can prevent cortical dyslamination, suggesting a prenatal therapeutic window.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.