Epilepsy News

FMCSA reviews 11 epilepsy waiver requests from commercial drivers - Eleven truck drivers with histories of epilepsy or seizure disorders are asking federal regulators for exemptions. The post FMCSA reviews 11 epilepsy waiver requests from commercial drivers appeared ...

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Understanding epilepsy: Seven ways to respond to an epileptic seizure - At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...

EPILEPSY AWARENESS: Local neurologist explains condition & seizure first aid - COLUMBUS, Ga. (WRBL) — Local experts say epilepsy is not a condition to be afraid of. Piedmont Columbus Regional pediatric neurologist Pierre Fequiere treats patients with epilepsy every day and knows ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Cognitive and behavioral clinical outcome assessments in children with developmental and epileptic encephalopathies: Issues and instruments - Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized. Advances in genomic technologies have transformed the diagnostic landscape of rare genetic epilepsies, including D...

Use of artificial intelligence in magnetic resonance imaging across the epileptic patient's journey: A meta-analysis of four clinical applications - OBJECTIVE: The application of artificial intelligence/machine learning (AI/ML) to magnetic resonance imaging (MRI) promises to enhance and support clinical decision-making in epilepsy. However, there currently lacks an appropriate assessment of clinical utility and study rigor of current AI/ML-driven models that are targeted toward supporting decision-making within the clinical workup in epilepsy.

Hypersensitivity reaction risk when restarting cenobamate after discontinuation: Insights from a prolonged hospitalized cohort - OBJECTIVE: To evaluate the risk of hypersensitivity reactions, including dermatological rashes, when cenobamate (CNB) is restarted at maintenance doses after temporary discontinuation.

Interictal epileptiform discharges in calcified neurocysticercosis-associated epilepsy: An exploratory study - The objective of the study was to assess the frequency of interictal epileptiform discharges (IEDs) in calcified neurocysticercosis (NCC) and its relationship with calcification burden. Forty-nine patients with calcified NCC (low-burden, 1-2 calcifications, n = 24; high-burden, ≥15 calcifications, n = 25) and seizure history underwent prolonged (8-h) electroencephalography (EEG), interpreted by...

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury - Astrocytes, glial cells in the brain, play a crucial role in maintaining brain homeostasis through functional gap junctions (GJs) primarily comprising connexin43 (Cx43). These GJs facilitate electrical and metabolic coupling between astrocytes. Dysregulation of Cx43 has been implicated in various pathologies, including traumatic brain injury (TBI) and acquired epilepsy. After mild TBI/concussio...

Predictive epileptology: the emergence of a new paradigm for the management of epileptic seizures - CONCLUSION: Wearable AI-based devices mark a fundamental shift in epilepsy management from reactive response to proactive risk management. While the technology has proven its great potential, it is not yet ready for mass clinical introduction due to existing technical and non-technical barriers. The future of this area lies in the development of integrated «closed-loop» systems that automatical...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.