Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Vagus nerve stimulation: anti-inflammatory effects in epilepsy -
CONCLUSION: VNS efficacy appears to be associated with a complex, multi-phasic biological response. The temporal dynamics of peripheral biomarkers may reflect a potential early stabilization of the blood-brain barrier, followed by delayed systemic immunomodulation. While blood-based analysis precludes direct conclusions regarding central neuroinflammation, the delayed reduction of circulating i...
Validation of the Persian NDDI-E for Depression Screening in Adolescents with Epilepsy - CONCLUSION: The Persian NDDI-E proves to be a valid and reliable screening tool for depression in adolescents with epilepsy, facilitating early detection and intervention in busy clinical settings. Routine screening is recommended to improve patient outcomes, though larger multicenter studies are needed to confirm these findings.
Hyperventilation-Induced High-Amplitude Rhythmic Slowing and Its Impact on Migraine Frequency in Children: A Retrospective Observational Cohort Study - CONCLUSION: This is the first study on the correlation of HIHARS with migraine in children. Patients aged 7 to 12 years old with HIHARS had more susceptibility to migraine headaches. It is suggested that children with HIHARS and a history of migraine in first-degree family members will be more susceptible to developing migraine in life.
Trans orbital eyebrow approach for selective resections in mesial temporal lobe epilepsy: Technical aspects and preliminary case series - CONCLUSION: Transorbital eyebrow approach is safe and effective for SAH, with a positive impact on cognitive functions and QOL. Although preliminary, these findings suggest that it may be an option in patients with pure MTLE.
The importance of genetic testing in managing developmental epileptic encephalopathy in resource-limited settings: a case report - CONCLUSION: Pathogenic variants of CACNA(1)E, particularly those causing either gain-of-function or loss-of-function effects, are linked to severe neurodevelopmental disorders. Clinically, CACNA(1)E mutations often present in early childhood with severe neurodevelopmental impairment, global developmental delay, autistic features, feeding difficulties, and self-injurious behaviors. The molecular...
Early reduction in unplanned healthcare utilization following vagus nerve stimulation for pediatric epilepsy - CONCLUSIONS: In a large, consecutive, single-surgeon series, pediatric VNS implantation was associated with an early reduction in unplanned acute healthcare utilization and an exceptional surgical safety profile. Our observations suggest that VNS provides a rapid and clinically significant reduction in unplanned seizure-related hospital admissions and ER visits within the first 3 months of impl...
Validation of the Persian NDDI-E for Depression Screening in Adolescents with Epilepsy - CONCLUSION: The Persian NDDI-E proves to be a valid and reliable screening tool for depression in adolescents with epilepsy, facilitating early detection and intervention in busy clinical settings. Routine screening is recommended to improve patient outcomes, though larger multicenter studies are needed to confirm these findings.
Hyperventilation-Induced High-Amplitude Rhythmic Slowing and Its Impact on Migraine Frequency in Children: A Retrospective Observational Cohort Study - CONCLUSION: This is the first study on the correlation of HIHARS with migraine in children. Patients aged 7 to 12 years old with HIHARS had more susceptibility to migraine headaches. It is suggested that children with HIHARS and a history of migraine in first-degree family members will be more susceptible to developing migraine in life.
Trans orbital eyebrow approach for selective resections in mesial temporal lobe epilepsy: Technical aspects and preliminary case series - CONCLUSION: Transorbital eyebrow approach is safe and effective for SAH, with a positive impact on cognitive functions and QOL. Although preliminary, these findings suggest that it may be an option in patients with pure MTLE.
The importance of genetic testing in managing developmental epileptic encephalopathy in resource-limited settings: a case report - CONCLUSION: Pathogenic variants of CACNA(1)E, particularly those causing either gain-of-function or loss-of-function effects, are linked to severe neurodevelopmental disorders. Clinically, CACNA(1)E mutations often present in early childhood with severe neurodevelopmental impairment, global developmental delay, autistic features, feeding difficulties, and self-injurious behaviors. The molecular...
Early reduction in unplanned healthcare utilization following vagus nerve stimulation for pediatric epilepsy - CONCLUSIONS: In a large, consecutive, single-surgeon series, pediatric VNS implantation was associated with an early reduction in unplanned acute healthcare utilization and an exceptional surgical safety profile. Our observations suggest that VNS provides a rapid and clinically significant reduction in unplanned seizure-related hospital admissions and ER visits within the first 3 months of impl...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.