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More Than a Daughter: Margaret A. Lennox-Buchthal (1913-2001), Epileptologist -
In a 2010 book chapter on the pioneering encephalographer Mary A.B. Brazier, PhD (1904-1995), a photo of a smiling woman is labeled "Margaret Lennox-Buchthal, wife of Fritz, daughter of William Lennox." Yet, like most women, Margaret Lennox-Buchthal, MD (1913-2001), was more than a wife and a daughter. She was an assistant professor at the Yale School of Medicine and associate professor at the ...
AI for Poststroke Epilepsy: Scoping Review of Imaging-Based Prediction Models and Implications for African Settings -
CONCLUSIONS: Imaging-based AI for predicting PSS and PSE has progressed rapidly, but important methodological and geographical gaps remain. Limited external validation, heterogeneous reporting, and the absence of African development and validation cohorts restrict confidence in the generalizability of existing models. Future research should prioritize the development of explainable imaging-base...
Routing to the seizure in postoperative human glioma cortex: spatio-temporal uncoupling between slow and fast extracellular neuronal activities -
CONCLUSIONS: In the periglioma human cortex, seizures arise from progressively recruited neuronal assemblies sculpted together with HFOs, providing new insights into the microphysiological processes of glioma-related ictogenesis and requiring consideration of the preictal fast and focal neuronal activity.
A novel de novo variant of CDKL5 in an Iranian child with infantile-onset refractory epilepsy -
CONCLUSION: The present study can expand the mutational spectrum of CDKL5 and highlight the clinical advantage of sequencing-based genetic testing for early diagnosis and personalized therapeutic management of refractory epilepsy.
Video EEG in pediatric epilepsy: Diagnostic significance and association between frequency band power and cognitive impairment severity -
CONCLUSION: VEEG demonstrated higher diagnostic performance than routine EEG, and EEG frequency band power was correlated with cognitive impairment severity.
Reversal of refractory epilepsy in an adult with GAMT deficiency: A case report and comparative literature review -
OBJECTIVE: Guanidinoacetate methyltransferase (GAMT) deficiency is a rare autosomal recessive creatine biosynthesis disorder. Reports specifically focusing on adult patients remain scarce.
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