Epilepsy and Seizure News
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Mechanistically informed circulating biomarkers are associated with acquired epilepsy after neonatal brain injury -
CONCLUSIONS: Across two cohorts, mechanistically informed biomarkers were associated with acquired epilepsy after neonatal seizures. IL-1β, UCHL1, and GH reflect inflammation, neuronal injury, and impaired trophic signaling, while circulating miRNAs provide complementary mechanistic insight. Findings support a translational biomarker panel and highlight inflammation as a biologically plausible ...
Clinical characteristics and prognosis of focal cortical dysplasia with epilepsy in children -
CONCLUSION: Most children with FCD-related epilepsy in this cohort achieved favorable postoperative outcomes. Epileptogenic focus resection, FCD type II pathology, and temporal lobe lesion location were identified as independent factors associated with good prognosis.
Novel Smartphone-Based Screening Tool for Absence Seizures in Pediatric Settings: A Comparative Study With Video EEG -
CONCLUSIONS: The Eysz HV Recorder is an accurate tool with high sensitivity and specificity for identifying absence seizures, which could aid clinicians in differentiating epileptic from nonepileptic staring spells.
Temporal trends, regional inequalities, and economic burden of epilepsy-related hospitalizations in brazil, 2010-2024: a nationwide ecological time-series analysis -
CONCLUSION: Epilepsy-related hospitalizations represent a growing and uneven burden in Brazil. Increasing hospitalization rates and rising in-hospital mortality highlight persistent gaps in both acute and outpatient care. These findings underscore the need for targeted strategies to reduce regional disparities and improve epilepsy management, particularly among older adults.
Arterial spin labeling in pediatric epilepsy in the emergency setting: clinical predictors of diagnostic yield and optimal acquisition time -
CONCLUSIONS: ASL can be useful in rapidly identifying focal seizure in emergency setting. Timely acquisition of ASL is crucial as cerebral perfusion changes are often transient, with potentially shorter time for hypoperfusion.
Investigation of the role of HSP70 immunohistochemical staining method to the diagnosis of sudden unexpected death in epilepsy in autopsies -
CONCLUSION: HSP70 staining of the hippocampus demonstrated significantly higher staining across all subtypes in SUDEP cases. The results indicate that HSP70 immunohistochemical staining provides significant support for SUDEP diagnosis and could be employed as an ancillary staining method in forensic medicine practices.
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