Epilepsy News

New fMRI neurofeedback study trains the brain to reduce depressive rumination - Major Depressive Disorder (MDD) is far from a cookie-cutter diagnosis. Different patients report suffering from different subsets of symptoms, yet most are ultimately prescribed the same first-line ...

Neurofeedback Trains Brain to Stop Depressive Rumination - A new study uses real-time fMRI neurofeedback to help depression patients reduce rumination by training specific brain circuits in a gamified environment.

Rewiring Your Brain: Neurofeedback Goes Mainstream - See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Will Strahl walked up to my door with a massive black briefcase in his ...

What Is Neurofeedback Therapy And How Does It Work? - Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...

Neurofeedback Therapists in The Woodlands, TX - Additionally, I am a certified practitioner for microcurrent neurofeedback. Are you feeling overwhelmed, stuck, or tired of carrying everything on your own? Life can feel heavy at times, and reaching ...

Inhibition of aerobic glycolysis suppresses ferroptosis via activation of the AMPK-FoxO3a pathway in epileptic rats - CONCLUSION: Inhibition of aerobic glycolysis attenuates seizure-induced ferroptosis through activation of the AMPK-FoxO3a pathway. These findings establish a mechanistic link between metabolic reprogramming and ferroptosis in epilepsy and suggest that targeting aerobic glycolysis may represent a promising therapeutic strategy for neuroprotection in epilepsy.

Insular morphological abnormalities in focal to bilateral tonic-clonic seizures - CONCLUSION: Our results supported brain network abnormalities related to FBTCS and highlighted the value of insula, particularly its subregions, in identifying FBTCS+ patients and predicting lateralization at the individual level.

5-(Benzofuran-2-yl)-3-(2-chloro-4-fluorobenzyl)-1,3,4-oxadiazol-2(3H)-one (GM-90663) Alleviates Dravet Syndrome via Inhibiting Monoamine Oxidase Activity - Dravet syndrome (DS) is a severe, catastrophic childhood epilepsy predominantly caused by loss-of-function mutations in the SCN1A gene, which encodes the voltage-gated sodium channel Na(v)1.1. In this study, we evaluated the therapeutic potential of 5-(Benzofuran-2-yl)-3-(2-chloro-4-fluorobenzyl)-1,3,4-oxadiazol-2(3H)-one (GM-90663), a novel small molecule designed to address the complex pathop...

Sleep Architecture and Microstructure in Childhood Absence Epilepsy: Clinical and Neurophysiological Perspectives - CONCLUSIONS: Sleep disturbances appear to represent an important component of the clinical phenotype of childhood absence epilepsy. Assessing the sleep architecture and sleep EEG microstructure, particularly sleep spindles, may provide insights into network dysfunction and cognitive vulnerability; however, further studies are needed to clarify their clinical utility.

Medication Adherence and Quality of Life in Epilepsy: The Potential Role of Seizure Severity in the Association Between Them - Background/Objectives: Epilepsy is a long-term condition that affects the brain and has a big impact on a person's daily life, especially in areas where people do not have a lot of money or access to good healthcare. This study aimed to evaluate the relationship between medication adherence and QoL and to assess the role of seizure severity in the association between them among patients with ep...

Microglia in Epilepsy: From Molecular Mechanism to Therapeutic Strategy - The limit of disease-modifying therapeutic strategies against epilepsy has prompted mainstream epilepsy research toward understanding the pathways contributing to epileptic seizures. Microglia, the powerhouse of the brain's innate immune system, is known for its role in epileptic seizures, contributing via neuroinflammation, neuronal death, and neurogenesis. Therapeutic targeting of microglia w...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.