Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Epilepsy and Seizure News
Seizure action plans: Management and educational tools in epilepsy care -
Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...
People with focal epilepsy often have seizures while driving before a diagnosis - Prior to being diagnosed with epilepsy, 5% of people with a type of epilepsy called focal epilepsy had a seizure while driving, according to a new study published in the June 7, 2023, online issue of ...
Living well with epilepsy: A diagnosis is not the end of the story - Over the past two weeks, we have explored what seizures and epilepsy are, corrected common myths, discussed seizure first aid, and examined the emotional, psychological, and cognitive challenges that ...
High Retention, Seizure-Freedom Rates for Perampanel in Epilepsy - NASHVILLE, Tennessee ―The retention rate for the antiseizure drug perampanel (Eisai Co, Ltd) is more than 70% for adult patients with epilepsy, new research shows. In early results from the PERPRISE ...
Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...
People with focal epilepsy often have seizures while driving before a diagnosis - Prior to being diagnosed with epilepsy, 5% of people with a type of epilepsy called focal epilepsy had a seizure while driving, according to a new study published in the June 7, 2023, online issue of ...
Living well with epilepsy: A diagnosis is not the end of the story - Over the past two weeks, we have explored what seizures and epilepsy are, corrected common myths, discussed seizure first aid, and examined the emotional, psychological, and cognitive challenges that ...
High Retention, Seizure-Freedom Rates for Perampanel in Epilepsy - NASHVILLE, Tennessee ―The retention rate for the antiseizure drug perampanel (Eisai Co, Ltd) is more than 70% for adult patients with epilepsy, new research shows. In early results from the PERPRISE ...
Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...
Medical News Today
PubMed
Changing Referral Patterns in Paediatric Neurology: A Tertiary Outpatient Study within Brazil's Unified Health System, 2014-2024 -
CONCLUSION: These findings suggest a change in the referral case-mix at a single tertiary paediatric neurology centre within the Brazilian SUS, characterised by a marked pre-pandemic rise in ASD referrals that stabilised at an elevated level, alongside shifts in the distribution of other neurological diagnoses.
Relative entropy as a biomarker for vagus nerve stimulation response in epilepsy: Insights from intracerebral electroencephalography - OBJECTIVE: This study aims to analyze differences in pre-implantation invasive electroencephalographic (IEEG) data between vagus nerve stimulation (VNS) responders (>50% seizure reduction) and VNS nonresponders (<50% seizure reduction).
Semiology of functional/dissociative seizures in idiopathic generalized epilepsy: An inpatient video-electroencephalographic study - OBJECTIVE: This study was undertaken to estimate the prevalence and characterize the semiology of co-occurring functional/dissociative seizures (FDSs) and identify clinical features potentially associated with the development of video-electroencephalography (video-EEG)-diagnosed FDSs in patients with idiopathic generalized epilepsy (IGE).
A CLN8 biallelic missense variant causes epilepsy with severe treatment-resistant psychosis - Epilepsy and psychosis are dysfunctions of the nervous system that may occasionally co-occur. The current study was designed to investigate the causes of psychosis with or without epilepsy in Pakistani families. We identified two consanguineous families in which all affected members had treatment-resistant psychosis while three patients also had epilepsy. Every participant was examined by psych...
Perineuronal net abnormalities in epileptic human tissue - OBJECTIVE: The extracellular matrix (ECM) performs several functions during development and in mature nervous tissue plasticity; ECM concentrates in lattice-like envelopes called perineuronal nets (PNNs), which surround the cell bodies and proximal dendrites, mainly of parvalbumin (PV) γ-aminobutyric acidergic interneurons. PNNs are proposed to serve synaptic plasticity regulation, synapse stab...
Cortical stimulation reveals effective disconnection of the epileptogenic network at seizure onset - OBJECTIVE: Seizure onset the transition from interictal to ictal network states-remains poorly understood despite decades of research. To date, most analyses of seizure onset rely on descriptors of passively recorded network variables such as spectral features or functional connectivity. However, direct causal analysis of brain network dynamics across the ictal transition have yet to be systema...
Relative entropy as a biomarker for vagus nerve stimulation response in epilepsy: Insights from intracerebral electroencephalography - OBJECTIVE: This study aims to analyze differences in pre-implantation invasive electroencephalographic (IEEG) data between vagus nerve stimulation (VNS) responders (>50% seizure reduction) and VNS nonresponders (<50% seizure reduction).
Semiology of functional/dissociative seizures in idiopathic generalized epilepsy: An inpatient video-electroencephalographic study - OBJECTIVE: This study was undertaken to estimate the prevalence and characterize the semiology of co-occurring functional/dissociative seizures (FDSs) and identify clinical features potentially associated with the development of video-electroencephalography (video-EEG)-diagnosed FDSs in patients with idiopathic generalized epilepsy (IGE).
A CLN8 biallelic missense variant causes epilepsy with severe treatment-resistant psychosis - Epilepsy and psychosis are dysfunctions of the nervous system that may occasionally co-occur. The current study was designed to investigate the causes of psychosis with or without epilepsy in Pakistani families. We identified two consanguineous families in which all affected members had treatment-resistant psychosis while three patients also had epilepsy. Every participant was examined by psych...
Perineuronal net abnormalities in epileptic human tissue - OBJECTIVE: The extracellular matrix (ECM) performs several functions during development and in mature nervous tissue plasticity; ECM concentrates in lattice-like envelopes called perineuronal nets (PNNs), which surround the cell bodies and proximal dendrites, mainly of parvalbumin (PV) γ-aminobutyric acidergic interneurons. PNNs are proposed to serve synaptic plasticity regulation, synapse stab...
Cortical stimulation reveals effective disconnection of the epileptogenic network at seizure onset - OBJECTIVE: Seizure onset the transition from interictal to ictal network states-remains poorly understood despite decades of research. To date, most analyses of seizure onset rely on descriptors of passively recorded network variables such as spectral features or functional connectivity. However, direct causal analysis of brain network dynamics across the ictal transition have yet to be systema...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.