Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Entraining chimeras: The effect of driving with regular, irregular, and real-world phases -
Chimera states in coupled oscillator networks are paradigmatic examples of partial synchronization in nonlinear systems, with direct relevance to real-world network dynamics, such as neuronal dynamics. Since real-world networks are not isolated, but embedded in larger interacting systems, chimeras have also been studied under the influence of other networks and external signals. In particular, ...
Clinical case of a pregnant woman with arteriovenous malformation, hemorrhagic venous infarcts and epileptic seizures: a case report - CONCLUSION: This clinical case presents interest due to the combination of medical conditions, which resulted in cerebrovascular incidents with different localizations and characteristics during pregnancy, complicated with epileptic seizures.
Perirhinal cortex gains control of hippocampal seizures via broad downstream circuits in male mouse models - The perirhinal cortex (PRh) has extensive interconnections with limbic structures, including the fasciola cinerea (FC), a recently identified node and therapeutic target in temporal lobe epilepsy. However, the neural circuit basis between PRh and FC in seizure progression remains unclear. Here we show that the PRh provides the principal excitatory input to the FC and plays an important role in ...
Gastrodin alleviates neuronal damage in epileptic cell models by targeting P2RY12 to inhibit microglial hyperactivation - Epilepsy is a chronic neurological disorder characterized by recurrent seizures, with its onset and progression closely linked to neuroinflammation, where abnormal activation and migration of microglia serve as a key pathological process. This study focuses on the regulatory role of gastrodin, the principal active component of the traditional Chinese medicine Gastrodia elata, and its target P2R...
The heartbeat evoked potential and the prediction of functional seizure semiology - Functional seizures (FSs) are common, but distinguishing FS from epileptic seizures (ESs) can be challenging, and the pathophysiology is not well-understood. The heartbeat evoked potential (HEP) reflects the central processing of cardiac signals and bodily attention. Our group previously demonstrated HEP differences between FS and ES. Here, we sought to replicate these HEP findings in an indepe...
Before attributing a positive effect to levetiracetam extended compared to immediate release, appropriately designed studies are necessary - No abstract
Clinical case of a pregnant woman with arteriovenous malformation, hemorrhagic venous infarcts and epileptic seizures: a case report - CONCLUSION: This clinical case presents interest due to the combination of medical conditions, which resulted in cerebrovascular incidents with different localizations and characteristics during pregnancy, complicated with epileptic seizures.
Perirhinal cortex gains control of hippocampal seizures via broad downstream circuits in male mouse models - The perirhinal cortex (PRh) has extensive interconnections with limbic structures, including the fasciola cinerea (FC), a recently identified node and therapeutic target in temporal lobe epilepsy. However, the neural circuit basis between PRh and FC in seizure progression remains unclear. Here we show that the PRh provides the principal excitatory input to the FC and plays an important role in ...
Gastrodin alleviates neuronal damage in epileptic cell models by targeting P2RY12 to inhibit microglial hyperactivation - Epilepsy is a chronic neurological disorder characterized by recurrent seizures, with its onset and progression closely linked to neuroinflammation, where abnormal activation and migration of microglia serve as a key pathological process. This study focuses on the regulatory role of gastrodin, the principal active component of the traditional Chinese medicine Gastrodia elata, and its target P2R...
The heartbeat evoked potential and the prediction of functional seizure semiology - Functional seizures (FSs) are common, but distinguishing FS from epileptic seizures (ESs) can be challenging, and the pathophysiology is not well-understood. The heartbeat evoked potential (HEP) reflects the central processing of cardiac signals and bodily attention. Our group previously demonstrated HEP differences between FS and ES. Here, we sought to replicate these HEP findings in an indepe...
Before attributing a positive effect to levetiracetam extended compared to immediate release, appropriately designed studies are necessary - No abstract
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.