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Long-term clinical outcomes of the Adams modification to the anatomical hemispherectomy for refractory epilepsy: A case series and global systematic review -
CONCLUSIONS: This study presents the largest systematic review of hemispherectomies to date and provides new insight into a surgical modification that influenced the evolution of modern epilepsy surgery.
Cerebral small vessel disease burden in late-onset epilepsy of unknown aetiology: insights from a prospective multicenter cohort -
CONCLUSION: In this thoroughly characterized cohort, moderate-to-severe cSVD was infrequent, with age identified as the sole risk factor. These findings support the hypothesis that cSVD may serve as a biomarker of brain aging. Further research is required to substantiate these results.
Epilepsy-associated labor force exclusion in a multi-ethnic neurology cohort -
CONCLUSIONS: In this single-center specialty-neurology cohort, epilepsy was associated with lower documented employment and higher recorded unemployment or disability than a contemporaneous comparator with other neurological conditions. These cross-sectional findings should be interpreted in the context of a clinically selected referral population and unmeasured neurological, functional, occupa...
Use of Purified Cannabidiol in Treatment-Resistant Pediatric Epilepsy: Beyond Lennox-Gastaut Syndrome, Dravet Syndrome, and Tuberous Sclerosis Complex -
CONCLUSIONS: Among our cohort of treatment-resistant pediatric epilepsy, purified CBD was efficacious in a broad range of pediatric epilepsies and was well tolerated as an adjunctive anti-seizure medication. This medication may be considered in pharmacoresistant pediatric epilepsies in conditions beyond its FDA-labeled indications.
Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review -
OBJECTIVE: A systematic review was conducted to synthesize current anatomo-clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence-based guidance for interpreting this ictal semiology during presurgical evaluation.
Prevalence of neuropsychiatric and seizure disorders in neurofibromatosis type 1: a systematic review and meta-analysis -
Neurofibromatosis type 1 (NF1) is associated with intellectual disability (ID), autism spectrum disorder (ASD), attention deficit hyperactivity disorder (ADHD), emotional and seizure disorders. However, published prevalence estimates vary widely. The aim of this meta-analysis was to estimate the prevalence of ID, ASD, ADHD, epileptic seizures and emotional disorders in NF1. A systematic search ...
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