Epilepsy News

The association of opioid use disorder with post-cerebral aneurysm rupture outcomes - CONCLUSIONS: Pre-existing OUD was associated with higher post-rupture mortality, seizures, myocardial infarction, and longer hospitalization. Further studies are needed to clarify mechanisms, better address residual confounding, and determine whether these associations persist across settings.

Assessment of gabapentin efficacy in patients with KCNQ2-developmental epileptic encephalopathy - KCNQ2‑related developmental epileptic encephalopathy (KCNQ2‑DEE) is characterized by intractable epilepsy, cognitive impairment, and behavioral problems, highlighting the urgent need for precision therapies. This study aimed to promote the clinical application of gabapentin, a known Kv7 channel opener, in KCNQ2‑DEE by evaluating its efficacy in four patients carrying different KCNQ2 variants. T...

Carrying the weight in silence: lived realities of epilepsy caregivers in Shai Osudoku and Ningo Prampram - CONCLUSION: The findings underscore the need for contextually grounded epilepsy care models that address the interplay of sociocultural beliefs, financial constraints, and barriers to healthcare access. Strengthening and improving caregiver support through accessible mental health services, targeted education, improved access to affordable antiseizure medications, and community-based stigma-red...

Use of medium-chain triglycerides in paediatric patients with drug-resistant epilepsy without ketogenic therapy - OBJECTIVE: This study aimed to evaluate the efficacy of a Medium Chain Triglyceride (MCT) add-on treatment in children with drug-resistant epilepsy (DRE).

Seizure outcomes after laser interstitial thermal therapy for pediatric extratemporal lobe epilepsy - CONCLUSIONS: This study demonstrated that LITT is a safe and effective treatment option for pediatric ETLE and may achieve acceptable rates of seizure freedom with a minimally invasive approach. Concordance between noninvasive imaging (particularly PET) with LITT targets was associated with favorable outcomes, underscoring the importance of thorough preoperative evaluations to determine appropr...

Every Second Counts: The School Nurse as a Health Educator - A Cross Sectional Observational Study - Background Schools are key environments for children's daily lives, where urgent events such as syncope, hypoglycemia, seizures, and minor trauma can occur. In Italy, the absence of school nurses and the lack of mandatory first aid training for all teachers place initial emergency management largely on educational staff, whose preparation is variable. Enhancing first aid culture and readiness i...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.