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Long and complex shadow childhood epilepsy casts over educational achievement -
No abstract
Utilization, tolerability, and perception of medical cannabis use in patients with seizures -
The aim of this study was to describe patterns of use and patient choice of medical cannabis products for the treatment of seizures. Included were individuals certified with seizures and dispensed medical cannabis products between July 1, 2015, and December 31, 2023. Data were abstracted from dispensing records and self-reports at each visit describing cannabis use, seizure frequency, comedicat...
Safety and adverse event profiles in neuromodulation therapies for drug-resistant epilepsy -
Drug-resistant epilepsy (DRE) is associated with clinical and psychosocial burdens, and non-pharmacological therapies play an important role when seizure control cannot be achieved with antiseizure medications alone. Neuromodulation therapies, including vagus nerve stimulation (VNS), deep brain stimulation (DBS), and responsive neurostimulation (RNS), have become important options for patients ...
Introducing the D-DAND scale: Development of a comprehensive caregiver-administered tool for Dravet syndrome comorbidities -
OBJECTIVE: The Dravet Disease-Associated Neuropsychiatric Disorders (D-DAND) scale is a new caregiver-administered interview designed to assess the wide range of developmental and behavioral comorbidities in Dravet syndrome (DS) beyond seizures. D-DAND's preliminary psychometric properties in a large patient sample are reported.
A smart mattress for detecting and correcting the prone position: A feasibility study toward night-time SUDEP prevention -
OBJECTIVE: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in otherwise healthy patients with epilepsy; about 70% occurs during sleep, and nearly 90% of patients are found prone (face-down). Following a nocturnal seizure, terminal apnea occurs between 2.5 and 10.8 min postictally (median ~ 5 min), defining a narrow but actionable window for intervention. Although body-...
Perils and progress in epilepsy surgery utilization: Twenty-five years later -
More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti-seizure medication (ASM) for drug-resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for evaluation-guidance that subsequent consensus has since br...
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