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NMDAR-antibody encephalitis: Seizure semiology and EEG findings -
BACKGROUND: N-methyl-D-aspartate receptor antibody encephalitis (NMDAR-Ab-E) is an autoantibody-mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability.
Sexual and reproductive health information needs of young adults with chronic conditions: a scoping review protocol -
OBJECTIVE: This scoping review aims to identify, map, and synthesize evidence on the sexual and reproductive health (SRH) information needs of youth 15-24 years living with epilepsy, congenital heart disease (CHD), or systemic lupus erythematosus (SLE) in the USA and Canada, and identify barriers and facilitators to access to SRH information and services.
Intraventricular schwannoma presenting with memory impairment and full neurological recovery after surgical resection: a case report -
CONCLUSIONS: This case highlights the exceptional rarity of intraventricular schwannomas and demonstrates that isolated transient memory impairment may represent an atypical presenting manifestation. Complete microsurgical excision remains the treatment of choice and is associated with excellent neurological outcomes. Awareness of this rare diagnosis may facilitate earlier recognition and appro...
Resection plus stereotactic radiosurgery versus stereotactic radiosurgery alone and control of brain metastasis-induced seizures -
CONCLUSIONS: Patients treated with S+SRS experienced fewer posttreatment seizures at 6 months than patients treated with SRS, despite larger index lesions in patients treated with S+SRS and prevalent antiseizure medication use in the entire study population. Although multivariable models showed no significant associations at 12 months or beyond, the role of resection in controlling BrM-induced ...
Efficacy and Safety of Perampanel in Patients With Brain Tumor-Related Epilepsy: A Systematic Review and Meta-Analysis -
PURPOSE OF REVIEW: Epileptic seizures are a common and often debilitating complication in patients with brain tumors, significantly affecting quality of life and clinical outcomes. Brain tumor-related epilepsy (BTRE) is characterized by complex pathophysiologic mechanisms, notably glutamate-mediated neuronal hyperexcitability within the peritumoral environment. Perampanel, a selective, noncompe...
MiRNA Dysregulation in Epilepsy: Bridging Molecular Mechanisms and Therapeutic Innovation -
MicroRNAs (miRNAs), small non-coding RNA molecules, have been considered as pivotal regulators of gene expression, influencing many biological functions, including nerve cell development, synaptic plasticity, and inflammatory responses. Their biogenesis involves a multi-step process, beginning with transcription by RNA polymerase II, followed by processing through Drosha and Dicer enzymes, culm...
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