Epilepsy News

Frequent Cannabis Use Tied to Greater Seizure Burden in Drug-Resistant Epilepsy - Frequent cannabis users with drug-resistant epilepsy have more convulsive seizures and require more antiseizure medications, but researchers caution that the findings do not establish causation.

Frequent cannabis use tied to more severe epilepsy - Adults with hard-to-treat epilepsy who used cannabis most days had more than twice as many convulsive seizures per year and became resistant to antiseizure medications more quickly than nonusers, ...

Frequent cannabis users developed drug-resistant epilepsy 13 years earlier than non-users: study - A recent study published in 'Epilepsia' has found link between frequent recreational cannabis use and worsening seizures in patients with epilepsy.

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Focal treatment-resistant epilepsy symptoms improved with antiseizure medication - Please provide your email address to receive an email when new articles are posted on . Monthly seizure frequency percentage reduction was 68.73% for the entire study cohort. For those followed up in ...

Every seizure can look and feel very different: NMU holds presentation on epilepsy and seizure training - The presentation hopes to clear up misconceptions regarding epilepsy and seizures as well as how to help those in need.

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model - OBJECTIVE: γ-Aminobutyric acidergic (GABAergic) parvalbumin-positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage-gated channels. Specifically, the Kv3.1 voltage-gated potassium channel, which is h...

Meduna and the origins of the idea that seizures can be therapeutic - Electroconvulsive therapy (ECT) has been well discussed in psychiatry as one of the oldest, yet still enduring and effective treatments for several psychiatric disorders, including depression, catatonia, mania, and psychoses. However, the intellectual history of ECT is much less known in the field of epilepsy, in spite of the fact that the therapy's origins are squarely in epilepsy neuropatholo...

Sleep macro-architecture in sleep-deprivation-sensitive and sleep-deprivation-insensitive juvenile myoclonic epilepsy: A polysomnographic study - OBJECTIVE: Sleep deprivation (SD) triggers seizures in only a subset of patients with juvenile myoclonic epilepsy (JME). We compared sleep macro-architecture between SD-sensitive and SD-insensitive JME patients and healthy controls.

Extracellular matrix and perineuronal nets in neural plasticity, memory, and epileptogenesis - In the mature brain, the extracellular matrix (ECM) molecules derived from neurons and glia accumulate in spatially distinct extracellular compartments, including a diffuse interstitial matrix and condensed perineuronal nets (PNNs), where they regulate receptor mobility, ion homeostasis, cell-surface signaling, structural stabilization, and experience-dependent synaptic remodeling. PNNs, in par...

Editorial: The network theory of epilepsy at twenty - No abstract

Anterior shoulder dislocation after tonic-clonic seizure - No abstract

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.