Epilepsy and Seizure News
The Campaign for a National Plan for Epilepsy Needs Your Help -
A future neurologist appeals for your support for the National Plan for Epilepsy to coordinate research and care to enable earlier diagnosis, better treatment, and hopefully a cure.
Seizure action plans: Management and educational tools in epilepsy care -
Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...
Seizure action plans: More than management tools for epilepsy -
Newswise — Historically, seizure action plans have focused on certain high-risk groups — such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters ...
Epilepsy Advocacy Network provides resources, plans fundraiser -
One in 26 people will develop epilepsy in their lifetime, and one 1 in 10 people will have a seizure. November is just around the corner, and that is Epilepsy Awareness Month. Carrie Jones and Kim ...
Patients engage with epilepsy monitor in real time, improving seizure detection -
A team has built an AI-based interface that enables real-time communication between patients and epilepsy monitoring devices. As part of a small clinical study at the University of Pennsylvania in ...
Using Seizure-Risk Forecasts to ID Best Time for Epilepsy Monitoring -
NASHVILLE, Tennessee ― Scheduling video-electroencephalography (vEEG) monitoring on the basis of personalized seizure risk forecasts may improve diagnostic accuracy, emerging research suggests. In a ...
Epilepsy Explained: Causes, Seizure Types, and Treatment Options for Better Control -
Egyptian fruit bats flew more slowly after eating alcohol-laced food. Now the urine strips that caught boozy wild chimps may be used on wild bats. Teen Heart Health Scores Average 68.3 in Ninth Grade ...
First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week -
Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...
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Viral Infection-Induced Epilepsy and the Gut Microbiome Crosstalk -
Viral infections of the central nervous system (CNS) pose a significant risk for seizures, and in some cases, long-term epileptogenesis. Seizure development following viral infection involves diverse CNS mechanisms, with emerging evidence that peripheral factors, including gut microbiome composition and immune-inflammatory responses, also contribute. The gut microbiome is a multifaceted ecosyst...
Epilepsy in paediatric neurofibromatosis type 1: clinical features and associated factors in a single-centere cohort -
CONCLUSIONS: In our cohort, epilepsy occurred in 4.74% of patients. Most had favorable seizure outcomes. Epilepsy was associated with cerebrovascular anomalies and neurodevelopmental comorbidities but not with NBOs or intracranial tumours. These findings suggest that children with NF1 and cerebrovascular abnormalities may warrant particular vigilance for seizures, while those with epilepsy shou...
Advances in neurological disease models and optimization of the laboratory animal environment for reproducible research -
Animal models of neurological diseases have evolved from phenotype-based systems to integrated platforms that link genetics, molecular signaling, synaptic physiology, neural circuits, behavior, and therapeutic responses. Simultaneously, increasingly precise phenotyping has revealed that experimental outcomes are strongly influenced by age, microbiological status, diet, housing, stress, previous...
Timing of Post-Stroke Seizures and Functional Outcomes: Exploring Gender-Based Disparities -
CONCLUSIONS: RSS, especially in females, and hemorrhagic stroke are high-risk predictors of disability. Targeted seizure prophylaxis and gender-sensitive rehabilitation strategies may improve outcomes. Prospective studies should validate these associations and explore underlying mechanisms.
Anti-Seizure Medication Monitoring in Pediatric Patients -
Therapeutic drug monitoring of anti-seizure medications (ASMs) in pediatric patients presents unique challenges and considerations. In this article, the authors discuss pediatric physiology and developmental pharmacokinetics in the context of ASMs. Thirteen ASMs are discussed, including information on the history, mechanism of action and pharmacokinetics, relevant drug interactions, adverse eff...
Design, synthesis, and biological evaluation of isatin-based benzenesulfonamides as carbonic anhydrase II/VII inhibitors with anticonvulsant activity -
Epilepsy remains a challenging neurological disorder, with a significant proportion of patients exhibiting resistance to current antiseizure medications. Herein, we report the rational design, synthesis, and biological evaluation of a new series of isatin-thiazolidine-2,4-dione hybrids bearing a pendant benzenesulfonamide moiety as potential antiepileptic agents targeting epilepsy-associated ca...
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