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Mesial temporal shape asymmetry as a neuro-imaging correlate of epilepsy in mild cognitive impairment and dementia -
Epilepsy is a common comorbidity of Alzheimer's disease (AD) and related dementias (ADRD). Both epilepsy and ADRD affect the mesial temporal structures in volume and morphology. Nonetheless, mesial temporal shape and volume asymmetry remain understudied in persons with dementia and mild cognitive impairment, collectively called persons with cognitive impairment (PWCI) and co-morbid epilepsy. We...
Network-guided resection of magnetic resonance imaging-negative mesial temporal epilepsy using gamma oscillation regularity-based transfer entropy analysis -
CONCLUSION: This case demonstrates that preoperative GOR analysis can noninvasively direct focused intraoperative network interrogation and that GOR-based TE-derived directed connectivity mapping can unmask mesial temporal epileptogenicity in MRI-negative cases, thereby guiding effective, tissue-sparing resections.
Centroparietal periodic sharp-wave discharges and biphasic complexes: Novel EEG biomarkers for early diagnosis of Rasmussen encephalitis -
CONCLUSIONS: This case underscores the prognostic value of recurrent focal periodic sharp-wave discharges and biphasic complexes as prodromal EEG biomarkers for RE, aligning with one prior study linking these biphasic complexes to early-stage disease (Beaumanoir et al., 1997). Early recognition of these patterns is essential. Early initiation of immunotherapy may prevent irreversible neurologic...
Long-Term Outcomes and Safety of Surgical Treatment Following Intracranial Electroencephalography Monitoring in Pediatric Epilepsy: A Single-Center Study -
CONCLUSION: This study demonstrated a good seizure outcome rate of 54.2% in pediatric patients who underwent surgical treatment following iEEG monitoring. No major perioperative complications related to iEEG implantation were observed, and no patients experienced permanent neurological deterioration in this cohort. These findings suggest that with careful electrode selection, precise placement ...
Prevalence of epilepsy and seizure history in Finnish neuropathologically examined medico-legal autopsy cases with acute head injuries -
OBJECTIVES: Epilepsy and traumatic brain injury have a bidirectional relationship. This study aimed to report the prevalences of antemortem epilepsy diagnosis, seizure history, epilepsy-related and traumatic neuropathological findings, as well as background characteristics, among neuropathologically examined medico-legal autopsy cases with acute head injuries.
Taenia solium development and host interactions in neurocysticercosis: a narrative mini review on mechanistic pathways to epileptogenesis -
Neurocysticercosis (NCC), a central nervous system infection caused by the larval stage of Taenia solium, remains a leading cause of acquired epilepsy in endemic regions. Mounting evidence indicates that seizure development in NCC is not solely driven by host inflammatory responses but reflects complex, dynamic interactions between parasite development, host neuroimmune processes, and neuronal ...
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