Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Three-Year Mortality After First Acute Symptomatic Seizure: A Prospective, Population-Based Study in Ireland -
BACKGROUND AND OBJECTIVES: Acute symptomatic seizures (ASyS) are clinical seizures occurring at the time of a systemic insult or in close temporal association with a documented brain injury. We aimed to determine the 3-year mortality following a first ASyS.
Cross-material memory prediction: Influence of preoperative visual memory on postoperative verbal memory change after left anterior temporal lobe resection in people with epilepsy - OBJECTIVE: Left anterior temporal lobe resection (TLR) in people with epilepsy is associated with a high risk of postoperative verbal memory decline. Whereas substantial evidence supports the role of preoperative verbal memory in predicting postoperative verbal memory change, the potential contribution of preoperative visual memory has been rarely investigated.
Comorbidity spectrum in children and youth with epilepsy based on a validated and classified population-based childhood epilepsy cohort - OBJECTIVE: This study was undertaken to describe the occurrence and distribution of medical, neurological, neurodevelopmental, and psychiatric comorbidities in children and youth with epilepsy (CYE) and risk factors of such conditions.
β-Hydroxybutyrate reduces neuronal excitability via GIRK channels - OBJECTIVE: The ketogenic diet is used to treat drug-resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure suppression remain understudied. β-Hydroxybutyrate (β-HB), a principal ketone body, exerts antiseizure effects, yet its downstream ionic mechanisms remain unclear.
The Five Sign: A hand posture suggesting insulo-opercular involvement in focal seizures - OBJECTIVE: The Five Sign is a previously underrecognized ictal hand posture characterized by full extension and spreading of the fingers. We aimed to determine its localizing value and underlying network basis in patients with drug-resistant focal epilepsy.
Uncovering Individual Language Vulnerability in Epilepsy Through Functional Connectivity Laterality - CONCLUSION: Our findings suggest an individual vulnerability of language networks to seizure burden, although this uncorrected, exploratory finding requires replication in larger, independent samples. Incorporating functional connectivity measures into presurgical clinical fMRI analysis may enhance our ability to predict and protect language function in patients with TLE by prioritizing further...
Cross-material memory prediction: Influence of preoperative visual memory on postoperative verbal memory change after left anterior temporal lobe resection in people with epilepsy - OBJECTIVE: Left anterior temporal lobe resection (TLR) in people with epilepsy is associated with a high risk of postoperative verbal memory decline. Whereas substantial evidence supports the role of preoperative verbal memory in predicting postoperative verbal memory change, the potential contribution of preoperative visual memory has been rarely investigated.
Comorbidity spectrum in children and youth with epilepsy based on a validated and classified population-based childhood epilepsy cohort - OBJECTIVE: This study was undertaken to describe the occurrence and distribution of medical, neurological, neurodevelopmental, and psychiatric comorbidities in children and youth with epilepsy (CYE) and risk factors of such conditions.
β-Hydroxybutyrate reduces neuronal excitability via GIRK channels - OBJECTIVE: The ketogenic diet is used to treat drug-resistant epilepsy, yet the molecular mechanisms coupling metabolic state to seizure suppression remain understudied. β-Hydroxybutyrate (β-HB), a principal ketone body, exerts antiseizure effects, yet its downstream ionic mechanisms remain unclear.
The Five Sign: A hand posture suggesting insulo-opercular involvement in focal seizures - OBJECTIVE: The Five Sign is a previously underrecognized ictal hand posture characterized by full extension and spreading of the fingers. We aimed to determine its localizing value and underlying network basis in patients with drug-resistant focal epilepsy.
Uncovering Individual Language Vulnerability in Epilepsy Through Functional Connectivity Laterality - CONCLUSION: Our findings suggest an individual vulnerability of language networks to seizure burden, although this uncorrected, exploratory finding requires replication in larger, independent samples. Incorporating functional connectivity measures into presurgical clinical fMRI analysis may enhance our ability to predict and protect language function in patients with TLE by prioritizing further...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.