Epilepsy News

Opinion | If a student had a seizure in the classroom, would your school be prepared? - "A parent whose child has epilepsy shouldn’t have to send an email in August asking whether anyone in the building knows what to do," high schooler Rishik Kondadadi writes.

The link between sleep, brain injury and seizures - New research is uncovering how sleep quality after traumatic brain injury (TBI) may be the key to preventing seizures and reducing the risk of post-traumatic epilepsy.

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Pediatrics in Brevard: Here's what to know about epilepsy, what to do if someone has seizure - Add Yahoo as a preferred source to see more of our stories on Google. More than 3.4 million people in the United States have epilepsy, so it is a relatively common diagnosis. In fact, it is the fourth ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Teacher with Epilepsy from Viral Seizure Video Shares Advice for Others Navigating Chronic Illness at Work (Exclusive) - For Yareli Jessica Gijon, one of the biggest lessons she’s learned while living with epilepsy is that asking for help is not a weakness. The 33-year-old California teacher, who recently went viral ...

Down syndrome-associated trisomic chromosomal regions modify amyloid-β accumulation and cause early death in a mouse model of aspects of Alzheimer's disease - BackgroundIndividuals with Down syndrome (DS), caused by triplication of chromosome 21 (Hsa21), face a significantly increased risk of early-onset Alzheimer's disease (AD) and epilepsy. However, the specific impact of Hsa21 genes on these risks is not yet fully understood.ObjectiveTo investigate how triplication of mouse chromosome 16 (Mmu16), homologous to Hsa21, affects amyloid-β (Aβ) accumul...

Relationship Between Patient Activation and Quality of Life in HCN1-Related Epilepsy - CONCLUSION: Increased patient activation is strongly associated with better HRQOL in HCN1-associated epilepsy. Interventions that enhance patient involvement, self-management, and disease awareness may improve psychosocial and clinical outcomes in these patients.

Depression in Epilepsy: Drug and Non-Drug Interventions Based on Multimodal Pathogenesis - Depression is a common comorbidity in patients with epilepsy, significantly impacting their quality of life. However, the precise mechanisms underlying depression in epilepsy remain unclear. This review synthesizes the latest research on the pathogenesis of depression in epilepsy, focusing on abnormalities in monoamine neurotransmitters, neuroinflammation, HypothalamicPituitary-Adrenal (HPA) ax...

Efficacy of oxcarbazepine in treating focal epilepsy based on resting-state EEG functional connectivity and power spectral analyses - CONCLUSIONS: These findings suggest that the response to oxcarbazepine in focal epilepsy is linked to differential regulation of slow-frequency brain networks. Persistent low-frequency synchronization reflects ongoing network instability and reduced treatment efficacy, whereas attenuation of pathological slow-wave activity indicates effective network stabilization. These band-limited spectral a...

Peripheral blood inflammatory biomarkers and response to vagus nerve stimulation in pediatric drug-resistant epilepsy: A retrospective cohort study - CONCLUSION: The efficacy of VNS in pediatric DRE is associated with systemic inflammatory dynamics. Postoperative changes in these inflammatory indices are associated with VNS treatment outcomes and may serve as a potential prognostic indicator for clinical response.

Carbonic anhydrase VII: Development of selective inhibitors and their pharmacological significance - Human carbonic anhydrase VII (hCA VII) is a cytosolic zinc metalloenzyme largely expressed in the brain, where it plays an important role in regulating intracellular pH. hCA VII emerged as a valuable therapeutic target for epilepsy and other neurological disorders due to its involvement in neuronal excitability and seizure generation. We provide a comprehensive outline of the structural feature...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.