Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Duration-dependent hippocampal structural changes in focal epilepsy: multicenter neuroimaging evidence -
CONCLUSIONS: We provide novel neuroimaging evidence supporting the duration-related structural alteration hypothesis of hippocampal structural changes in focal epilepsy. These findings may help explain the higher proportion of HS observed in adult surgical cohorts compared to pediatric surgical cohorts and enhance understanding of epilepsy pathophysiology, suggesting that disease duration is si...
Quality, reliability, and treatment misinformation risk of epilepsy content on Chinese short-video platforms TikTok (Douyin) and Bilibili: a cross-sectional analysis - Epilepsy is one of the most prevalent chronic neurological disorders worldwide, affecting approximately 70 million people globally and imposing substantial burdens on patients, families, and healthcare systems. Its multifaceted treatment landscape spanning antiepileptic drug (AED) therapy, epilepsy surgery, ketogenic dietary therapy, and neuromodulation makes accurate health information critica...
Audio-recorded stereotyped nocturnal choking vocalisations suggesting insular epilepsy - No abstract
Compound heterozygous variants in IRAK4 cause IRAK4 deficiency characterized by recurrent bacterial infections, brain calcification, and severe epilepsy - IRAK4 deficiency is a rare autosomal recessive inborn error of immunity caused by disruption of Toll-like receptor (TLR) signaling, and characterized by recurrent pyogenic bacterial infections and impaired inflammatory responses. Here, we reported an 11-year-old boy presenting with recurrent fever, rare severe brain calcification, and seizures. The persistently elevated C-reactive protein (CRP)...
Network Toxicology, Molecular Docking, and Molecular Dynamics to Explore the Epilepsy Mechanism Induced by Tetramine Poisoning - Tetramine poisoning commonly leads to epilepsy, with complex underlying mechanisms and poor treatment outcomes. This study aimed to explore the mechanisms of epilepsy induced by tetramine poisoning via network toxicology and molecular docking approaches. Tetramine poisoning targets were obtained from the SuperPred database, whereas epilepsy-related gene targets were identified through the GeneC...
Concurrent use of ketogenic diet therapy and cannabidiol in children and adults with epilepsy: A multicenter retrospective cohort study - Cannabidiol (CBD) and Ketogenic Diet Therapy (KDT) are evidence-based treatments for pharmacoresistant epilepsy with growing popularity in recent years. Even though CBD and KDT are used for many of the same indications, there is only limited research that characterizes the interactions between these two treatments. We conducted a retrospective chart review of subjects who were treated for epile...
Quality, reliability, and treatment misinformation risk of epilepsy content on Chinese short-video platforms TikTok (Douyin) and Bilibili: a cross-sectional analysis - Epilepsy is one of the most prevalent chronic neurological disorders worldwide, affecting approximately 70 million people globally and imposing substantial burdens on patients, families, and healthcare systems. Its multifaceted treatment landscape spanning antiepileptic drug (AED) therapy, epilepsy surgery, ketogenic dietary therapy, and neuromodulation makes accurate health information critica...
Audio-recorded stereotyped nocturnal choking vocalisations suggesting insular epilepsy - No abstract
Compound heterozygous variants in IRAK4 cause IRAK4 deficiency characterized by recurrent bacterial infections, brain calcification, and severe epilepsy - IRAK4 deficiency is a rare autosomal recessive inborn error of immunity caused by disruption of Toll-like receptor (TLR) signaling, and characterized by recurrent pyogenic bacterial infections and impaired inflammatory responses. Here, we reported an 11-year-old boy presenting with recurrent fever, rare severe brain calcification, and seizures. The persistently elevated C-reactive protein (CRP)...
Network Toxicology, Molecular Docking, and Molecular Dynamics to Explore the Epilepsy Mechanism Induced by Tetramine Poisoning - Tetramine poisoning commonly leads to epilepsy, with complex underlying mechanisms and poor treatment outcomes. This study aimed to explore the mechanisms of epilepsy induced by tetramine poisoning via network toxicology and molecular docking approaches. Tetramine poisoning targets were obtained from the SuperPred database, whereas epilepsy-related gene targets were identified through the GeneC...
Concurrent use of ketogenic diet therapy and cannabidiol in children and adults with epilepsy: A multicenter retrospective cohort study - Cannabidiol (CBD) and Ketogenic Diet Therapy (KDT) are evidence-based treatments for pharmacoresistant epilepsy with growing popularity in recent years. Even though CBD and KDT are used for many of the same indications, there is only limited research that characterizes the interactions between these two treatments. We conducted a retrospective chart review of subjects who were treated for epile...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.