Epilepsy News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Seizure action plans: More than management tools for epilepsy - Newswise — Historically, seizure action plans have focused on certain high-risk groups — such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

Video EEG in pediatric epilepsy: Diagnostic significance and association between frequency band power and cognitive impairment severity - CONCLUSION: VEEG demonstrated higher diagnostic performance than routine EEG, and EEG frequency band power was correlated with cognitive impairment severity.

Reversal of refractory epilepsy in an adult with GAMT deficiency: A case report and comparative literature review - OBJECTIVE: Guanidinoacetate methyltransferase (GAMT) deficiency is a rare autosomal recessive creatine biosynthesis disorder. Reports specifically focusing on adult patients remain scarce.

Frequent involvement of cingulate and insulo-opercular regions in sleep-related hypermotor epilepsy: A multimodal presurgical study - OBJECTIVE: Sleep-related hypermotor epilepsy (SHE) is classically considered a frontal lobe epilepsy; however, accumulating evidence suggests that hypermotor seizures may arise from multiple frontal and extrafrontal regions. We characterized the anatomical distribution of best available localizations in patients with SHE using multimodal presurgical data.

Epileptic seizure onset early warning using a lightweight multimodal self-explainable neural network - BackgroundCutting-edge deep learning algorithms are applied to epileptic seizures to uncover hidden patterns and achieve high accuracy. Post hoc algorithms explain black-box models but do not reveal the detailed workings of the algorithms. Therefore, intrinsic methods overcome these issues; however, they suffer from improper use of indicative metrics and performance-to-accuracy trade-offs.Objec...

Empagliflozin in Lafora disease: A first-in-human 6-month pilot study with electroclinical and FDG-PET findings - OBJECTIVE: Lafora disease (LD) is a rare, fatal neurodegenerative epilepsy with no approved treatments. Empagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, has shown neuroprotective actions in preclinical models through modulation of glycogen metabolism, induction of a pseudo-ketogenic state, improved mitochondrial efficiency, and reduction of excitatory neurotransmission. Based ...

The First Report of a Bang-Sensitive Strain in Drosophila funebris: Molecular-Genetic and Lipidomic Characterization - Bang sensitivity (BS) is a well-characterized seizure-and-paralysis phenotype in Drosophila melanogaster, but its genetic basis remains unexamined in the phylogenetically distant sister species Drosophila funebris. Here, we identify a naturally occurring BS strain in D. funebris from a wild population near Lake Valday, characterized by acute mechanical shock-induced seizures and paralysis, and ...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.