Epilepsy News
Recent news about epilepsy, seizures and treatments.
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Epilepsy and Seizure News
Seizure action plans: Management and educational tools in epilepsy care -
Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...
New genetic switch could improve gene therapy for drug-resistant epilepsy - Epilepsy affects more than 50 million people worldwide, making it one of the most common neurological disorders. Although medication helps many patients achieve seizure control, approximately ...
Intermountain Health doctors perform 100th surgery using brain implants to improve epilepsy symptoms - SALT LAKE CITY (ABC4) — Intermountain Health neurologists are celebrating a major surgical milestone: the 100th use of an implantable device that reduces seizure activity in patients with focal ...
Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...
New tools map seizures in the brain, improve epilepsy treatment - Two new models could solve a problem that's long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part ...
EU epilepsy care gap leaves 40% with treatable seizures - As the EU turns global brain health commitments into national action, member states remain far apart on epilepsy care ...
High Retention, Seizure-Freedom Rates for Perampanel in Epilepsy - NASHVILLE, Tennessee ―The retention rate for the antiseizure drug perampanel (Eisai Co, Ltd) is more than 70% for adult patients with epilepsy, new research shows. In early results from the PERPRISE ...
New genetic switch could improve gene therapy for drug-resistant epilepsy - Epilepsy affects more than 50 million people worldwide, making it one of the most common neurological disorders. Although medication helps many patients achieve seizure control, approximately ...
Intermountain Health doctors perform 100th surgery using brain implants to improve epilepsy symptoms - SALT LAKE CITY (ABC4) — Intermountain Health neurologists are celebrating a major surgical milestone: the 100th use of an implantable device that reduces seizure activity in patients with focal ...
Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...
New tools map seizures in the brain, improve epilepsy treatment - Two new models could solve a problem that's long frustrated millions of people with epilepsy and the doctors who treat them: how to find precisely where seizures originate to treat exactly that part ...
EU epilepsy care gap leaves 40% with treatable seizures - As the EU turns global brain health commitments into national action, member states remain far apart on epilepsy care ...
High Retention, Seizure-Freedom Rates for Perampanel in Epilepsy - NASHVILLE, Tennessee ―The retention rate for the antiseizure drug perampanel (Eisai Co, Ltd) is more than 70% for adult patients with epilepsy, new research shows. In early results from the PERPRISE ...
Medical News Today
PubMed
Todd's Paralysis Simulating Acute Ischemic Stroke: A Case Report -
Todd's paralysis is a transient focal neurological deficit following epileptic seizures that may closely mimic an acute ischemic stroke, posing a diagnostic challenge in the emergency department. We report the case of a 32-year-old woman with a history of epilepsy who presented with persistent expressive aphasia and right hemiparesis after experiencing multiple generalized tonic-clonic seizures...
Following Severe Pediatric Malaria, Epilepsy Screening Is Needed Even Among Children Without Coma: Findings From a Prospective Cohort Study - CONCLUSIONS: CNS-M presentation was twice as frequent as CM at this district hospital. Quantitative EEG supports CM as a more severe acute illness, but PME developed in 15-20% of children within one year regardless of malarial coma. These findings suggest that severe malaria with neurologic involvement-regardless of coma during acute presentation-has significant secondary epilepsy risk.
Gut microbiome alterations in canine idiopathic epilepsy: a pairwise case-control study - CONCLUSION: Our findings suggest a relationship between gut microbiomes and IE. However, the specific mechanism needs to be further investigated.
Single-nucleus transcriptomics-based drug screening platform for focal cortical dysplasia - Focal cortical dysplasias (FCDs) are a major cause of drug-resistant epilepsy, yet their molecular and pathological complexity has limited the development of effective antiseizure medications. Here, we performed single-nucleus RNA sequencing on 49 human neocortical specimens spanning FCDI-III. We identified prominent transcriptional alterations in non-neuronal populations, particularly astrocyt...
Clinical practices in prehospital rescue medication use for pediatric status epilepticus in Japan: a nationwide questionnaire survey - CONCLUSIONS: Prehospital rescue medication prescribing is primarily guided by seizure duration rather than diagnostic categories. Variability in caregiver instructions highlights the need for clearer guidance to optimize prehospital seizure management.
Beyond response rates: Residual seizure burden and willingness to undergo vagus nerve stimulation again in drug-resistant epilepsy - CONCLUSIONS: Willingness to undergo VNS again was associated with relative improvement and lower postoperative residual seizure burden. These findings suggest that residual seizure burden may provide complementary patient-centered information when interpreted alongside conventional response measures and established patient-reported outcomes.
Following Severe Pediatric Malaria, Epilepsy Screening Is Needed Even Among Children Without Coma: Findings From a Prospective Cohort Study - CONCLUSIONS: CNS-M presentation was twice as frequent as CM at this district hospital. Quantitative EEG supports CM as a more severe acute illness, but PME developed in 15-20% of children within one year regardless of malarial coma. These findings suggest that severe malaria with neurologic involvement-regardless of coma during acute presentation-has significant secondary epilepsy risk.
Gut microbiome alterations in canine idiopathic epilepsy: a pairwise case-control study - CONCLUSION: Our findings suggest a relationship between gut microbiomes and IE. However, the specific mechanism needs to be further investigated.
Single-nucleus transcriptomics-based drug screening platform for focal cortical dysplasia - Focal cortical dysplasias (FCDs) are a major cause of drug-resistant epilepsy, yet their molecular and pathological complexity has limited the development of effective antiseizure medications. Here, we performed single-nucleus RNA sequencing on 49 human neocortical specimens spanning FCDI-III. We identified prominent transcriptional alterations in non-neuronal populations, particularly astrocyt...
Clinical practices in prehospital rescue medication use for pediatric status epilepticus in Japan: a nationwide questionnaire survey - CONCLUSIONS: Prehospital rescue medication prescribing is primarily guided by seizure duration rather than diagnostic categories. Variability in caregiver instructions highlights the need for clearer guidance to optimize prehospital seizure management.
Beyond response rates: Residual seizure burden and willingness to undergo vagus nerve stimulation again in drug-resistant epilepsy - CONCLUSIONS: Willingness to undergo VNS again was associated with relative improvement and lower postoperative residual seizure burden. These findings suggest that residual seizure burden may provide complementary patient-centered information when interpreted alongside conventional response measures and established patient-reported outcomes.
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.
Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.