Epilepsy and Seizure News
Seizure action plans: Management and educational tools in epilepsy care -
Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...
Using Seizure-Risk Forecasts to ID Best Time for Epilepsy Monitoring -
NASHVILLE, Tennessee ― Scheduling video-electroencephalography (vEEG) monitoring on the basis of personalized seizure risk forecasts may improve diagnostic accuracy, emerging research suggests. In a ...
Seizure or epilepsy? Understanding the critical difference could save lives -
A sudden episode of shaking, confusion, or loss of awareness can be frightening - but does it mean epilepsy? Understanding the difference between a seizure and epilepsy is crucial for timely treatment ...
Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time -
Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...
NEURELIS PRESENTS STUDIES ON SEIZURE CLUSTERS AT THE AMERICAN EPILEPSY SOCIETY ANNUAL MEETING -
SAN DIEGO, Dec. 6, 2024 /PRNewswire/ -- Neurelis, Inc., today announced details of its presentations at the American Epilepsy Society (AES) Annual Meeting to be held December 6-10 in Los Angeles. The ...
The brain has its own thermostat. A study shows epilepsy may interfere with it -
Doctors have long known that changes in body temperature can affect seizure activity. Fever can trigger seizures in some young children, while in rare forms of epilepsy, bathing in hot water can bring ...
Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? -
Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...
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Instrumental activities of daily living in older adults with epilepsy: A cross-sectional and longitudinal multicenter study -
OBJECTIVE: Instrumental activities of daily living (IADLs) represent a critical but understudied measure of day-to-day function in people with epilepsy (PWE). In the multicenter Brain Aging and Cognition in Epilepsy (BrACE) study of PWE ≥55 years of age, we examined the proportion, clinical correlates, epilepsy-related predictors, and longitudinal trajectory of IADL impairment.
Excess mortality and causes of death of people with epilepsy in rural China: A nationwide cohort study -
OBJECTIVE: Epilepsy is associated with increased risk of excess mortality compared to the general population. Identifying causes of death is critical for guiding prevention strategies. Earlier studies in resource-limited settings suggested that accidental deaths were the main causes, but whether the mortality pattern has changed over time remains unclear. This study aimed to update the knowledg...
Functional (dissociative) seizures in PCDH19-clustering epilepsy: Clinical characteristics and diagnostic challenges -
OBJECTIVE: Functional (dissociative) seizures (FDS) are increasingly recognized among individuals with epilepsy, intellectual disability (ID), and psychiatric disorders, but their occurrence in PCDH19-clustering epilepsy (CE) has not been systematically described. We aimed to characterize the clinical features, diagnostic pathways, and management of FDS in individuals with genetically confirmed...
A randomized controlled trial of a multimodality digital health intervention to aid the delivery of the modified ketogenic diet therapy for epilepsy: The Keto eCoach trial protocol -
OBJECTIVE: Dietary therapy is an effective treatment for drug-resistant epilepsy; however, low adherence presents a significant barrier to use in the clinical setting. This study aims to evaluate a multimodality digital health intervention to overcome this barrier and improve outcomes in adults undertaking the modified ketogenic diet for epilepsy.
Invasive network neuromodulation for insular epilepsy: A three-center retrospective study -
To characterize invasive neuromodulation for insular drug-resistant epilepsy, we retrospectively evaluated 22 patients treated with responsive neurostimulation (RNS; n = 14) or chronic subthreshold stimulation (CSS; n = 8). Stereoelectroencephalography was performed in 20 cases (91%). Median baseline seizure frequency was 10.5/month. Forty-one percent had prior epilepsy surgery. At year 3, medi...
Integrating rare and common variation in epilepsy genetics: from genetic architecture to penetrance and clinical expressivity -
Epilepsy genetics has often been interpreted through a useful but simplified dichotomous framework in which severe epilepsies, particularly developmental and epileptic encephalopathies, are attributed mainly to rare, high-effect variants, whereas more common epilepsies are viewed as arising largely from the cumulative effects of common, small-effect variation. Although this framework has been i...
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