Epilepsy and Seizure News
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Bellevue Therapist Beverly Brashen, Ph.D. Offers Specialized Insomnia Treatment and Neurofeedback Therapy for Trauma and Chronic Sleep Disorders Across Greater Seattle -
The integrative therapist at beverlybrashen.com combines neurofeedback, CBT-I, somatic therapy, trauma-informed care, ...
Rewiring Your Brain: Neurofeedback Goes Mainstream -
See more of our trusted coverage when you search. Prefer Newsweek on Google to see more of our trusted coverage when you search. Will Strahl walked up to my door with a massive black briefcase in his ...
What Is Neurofeedback? -
Whenever I mention that neurofeedback helped me regain my life after my multiple brain injuries — or that I’m now a neurofeedback provider — the first reaction is to ask me, what is neurofeedback? I’m ...
Elite athletes enhance their performance with 'neurofeedback'—and you can get a device for $99 -
When you think of the training tools that professional athletes have at their disposal, high-tech sports equipment and state-of-the-art athletic facilities come to mind. But training for peak ...
What Is Neurofeedback Therapy And How Does It Work? -
Ashwini Nadkarni, M.D., is a board-certified psychiatrist, Assistant Professor at Harvard Medical School and Interim Vice Chair for Faculty Affairs in the Department of Psychiatry at Brigham and Women ...
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PubMed
State-Dependent Modulation of Neurotransmitter Systems in Epilepsy: A Mechanistic Framework for Seizure Dynamics and Biomarker Variability -
Epilepsy is increasingly conceptualized as a disorder of dynamic network instability rather than a static imbalance between excitation and inhibition. However, substantial variability in seizure occurrence, clinical expression, and treatment response remains insufficiently explained by existing models. This narrative review examines how neurotransmitter systems contribute to seizure dynamics wi...
Cannabidiol reduces atypical absence seizures and epileptic spasms in a Gabrb3(+/D120N) mouse model of Lennox-Gastaut syndrome -
OBJECTIVE: Lennox-Gastaut syndrome (LGS) is a drug-resistant developmental and epileptic encephalopathy (DEE). Preclinical drug development for LGS is constrained by a lack of syndrome-relevant animal models. We aimed to evaluate a Gabrb3^(+/D120N) knock-in (KI) mouse model of LGS by quantifying atypical absence seizures and epileptic spasms and assessing their sensitivity to antiseizure agents.
Pediatric epilepsy surgery: Global survey of invasive explorations -
OBJECTIVE: Invasive presurgical evaluation plays a key role in pediatric epilepsy surgery, particularly in magnetic resonance imaging (MRI)-negative cases, by guiding resective, disconnective, or ablative procedures. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Taskforce study provides an updated global overview of current invasive evaluation practices.
Seizure relapse in new onset epilepsy: It is not always drug resistance -
OBJECTIVE: Seizure recurrence in new onset epilepsy (NOE) can result from various factors. Although drug ineffectiveness is frequently investigated, other causes-such as nonadherence, inadequate treatment, nonepileptic events (e.g., functional/dissociative), or acute symptomatic seizures-also impact patient outcomes. This retrospective, longitudinal single-center study evaluated relapse causes ...
The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI -
OBJECTIVE: Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication-resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized equipment and expertise. Prior EEG-fMRI work has shown t...
Epilepsy surgery in pediatric patients with complex COL4A1/2-associated epilepsy -
OBJECTIVE: Pathogenic variants in COL4A1/2 compromise vascular basement membrane integrity, causing intrauterine hemorrhage and infarction leading to extensive structural brain lesions. Vascular disruptions during critical windows of neuronal migration can result in malformations of cortical development (MCD), which may drive epileptogenicity. While surgery is established for drug-resistant foc...
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