Epilepsy News

Disinformation and misinformation in epilepsy: An analysis of multiplatform short-form social media video content - OBJECTIVE: Short-form social media content is increasing in popularity but is at risk for propagating health-related disinformation/misinformation. We aimed to quantify epilepsy-related disinformation/misinformation on three such platforms: TikTok, Instagram Reels, and YouTube Shorts.

CT perfusion abnormalities in status epilepticus: associations with clinical characteristics, EEG, and outcome measures - CONCLUSION: CTP may serve as a useful tool for early triage in centers with limited neurophysiological resources and may help suggest nonconvulsive SE in diagnostically unclear cases. Hyperperfusion on CTP appears to reflect disease severity and prolonged seizure activity rather than brain injury. Ictal EEG patterns can be associated with both hyperperfusion and hypoperfusion. CTP abnormalities...

Prevalence of sleep and mood disorders in people with epilepsy: A single-Center self-reported assessment - OBJECTIVE: This study was designed to assess the prevalence of sleep and mood disturbances and their impact on quality of life (QoL) in a real-life cohort of people with epilepsy (PwE) followed at a tertiary epilepsy center using self-reported assessments.

New insights from MRI-guided laser interstitial thermal therapy for refractory epilepsy: a state-of-the-art overview - CONCLUSION: This overview provides comprehensive evidence on the application of MRgLITT for DRE). The evidence indicates a seizure freedom rate ranging from 18.87% to 75.86% with certainty levels raning from critically low to low. While these findings are promising, further primary and secondary studies are essential to establish definitive conclusions and assess the potential for future clinic...

Clinical heterogeneity and immunotherapy outcomes in anti-GAD65 antibody-associated autoimmune encephalitis: a retrospective study - Anti-glutamic acid decarboxylase 65 (GAD65) antibody-associated autoimmune encephalitis (AE) is characterized by diverse neurological manifestations and systemic autoimmune comorbidities, posing diagnostic and therapeutic challenges. This study aimed to investigate the clinical heterogeneity, immunological characteristics, neuropathological features, and therapeutic outcomes in patients with an...

Electroencephalographic abnormalities and clinical phenotypes in children with autism spectrum disorder: a single center cohort study - CONCLUSION: Non-paroxysmal EEG abnormalities may represent a distinct neurophysiological correlate of sleep disorders in children with ASD. Comorbid epilepsy is strongly associated with intellectual disability severity, supporting the need for comprehensive neurological evaluation in this population. While broad categorical EEG patterns did not reveal significant associations with most clinical...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.