Epilepsy News

CREATe Therapeutics Achieves Complete Seizure Prevention in a Severe Model of Focal Epilepsy - Breakthrough Preclinical Result in Epilepsy Treatment These findings strengthen our confidence as we progress toward ...

After Epilepsy Surgery, When to Stop ASMs Matters - A multicenter cohort study explores how the timing of ASM withdrawal after epilepsy surgery may influence seizure relapse and long-term outcomes.

Can Epilepsy Be Cured? A Neurologist Explains What Seizure-Free Really Means - What does it truly mean to be seizure-free A Neurologist explains the difference between remission and a cure and the latest treatment options for managing the condition ...

Pediatrics in Brevard: Here's what to know about epilepsy, what to do if someone has seizure - More than 3.4 million people in the United States have epilepsy, so it is a relatively common diagnosis. In fact, it is the fourth-most common neurologic condition in the world. November is National ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

Doctor explains: How childhood epilepsy often goes undetected and what parents must know - Epilepsy remains one of the most common neurological disorders globally. Firstpost brings out experts’ views on signs, developmental impact, rural-urban treatment gaps and how AI and precision ...

Understanding epilepsy: Seven ways to respond to an epileptic seizure - At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...

Focal treatment-resistant epilepsy symptoms improved with antiseizure medication - Please provide your email address to receive an email when new articles are posted on . Monthly seizure frequency percentage reduction was 68.73% for the entire study cohort. For those followed up in ...

Rewiring Your Brain: Neurofeedback Goes Mainstream - Will Strahl walked up to my door with a massive black briefcase in his hand, the kind you could use to tote a dirty bomb. Once inside my living room, he cracked open the case and removed a laptop, a ...

High-precision neurofeedback accelerates the mental health benefits of meditation - A new study published in the journal Mindfulness has found that high-precision brain training can help novice meditators learn the practice more effectively. The findings indicate that neurofeedback ...

Neurofeedback for ADHD: Significant, Lasting Improvement - Computer-based neurofeedback can produce significant and lasting improvement in attention and focus in children with attention-deficit/hyperactivity disorder (ADHD ...

Neurofeedback Gains Popularity and Lab Attention - You sit in a chair, facing a computer screen, while a clinician sticks electrodes to your scalp with a viscous goop that takes days to wash out of your hair. Wires from the sensors connect to a ...

Understanding The Role Of Neurofeedback Technology In Addressing ADHD - Attention-deficit/hyperactivity disorder (ADHD) is a prevalent challenge in today's educational and professional landscapes. Most of us are familiar with ADHD, either ...

Probiotics and seizure susceptibility in preclinical epilepsy models: mechanistic insights from a systematic review and meta-analysis - The gut microbiota can affect neuronal excitability, inflammation, and oxidative balance via the gut-brain axis, shaping seizure susceptibility. To translate these findings into clinical approaches, a synthesis of preclinical microbiome-based evidence is needed. This systematic review and meta-analysis examined the putative anticonvulsant, anti-inflammatory, antioxidant, and neuroprotective eff...

Investigating the role of cortical microglia in a mouse model of viral infection-induced seizures - Microglia, resident immune sentinels in the brain, are crucial in responding to tissue damage, infection, damage signals like purines (ATP/ ADP), and clearing cellular debris. It is currently unknown how microglial reactivity progresses and contributes to seizure development following Theiler's Murine Encephalomyelitis Virus (TMEV) infection. Previously, it has been demonstrated that purinergic...

Diagnosis of the first seizure-like events in children from third-tier cities in southwestern China: a retrospective cohort study - CONCLUSIONS: Although we aimed to identify risk factors applicable to resource-limited areas, we found that only high seizure frequency, abnormal video-EEG findings and structural brain MRI abnormalities independently predicted a subsequent diagnosis of epilepsy. These findings underscore the need for targeted paediatrician training, as well as increased financial investment in resource-limited...

Ido1 and Ido2 deficiencies attenuate kainic acid-induced ictogenesis - Insults to the brain in the form of injury, infection and exposure to seizurogenic chemicals can induce seizures (ictogenesis). Seizure episodes during any of these events is one of the biggest risk factors for the development of treatment-resistant epilepsy, making the acute ictogenic period a critical time for intervention. Indoleamine-2,3-dioxygenases (Ido1 & Ido2) modulate systemic and cent...

Senescence markers in peripheral blood mononuclear cells in pediatric drug-resistant epilepsy - CONCLUSION: We observed no evidence of established stress-induced premature or replicative senescence in drug-resistant epilepsy patients. However, elevated proinflammatory cytokines and high p21/p16 expression in the drug-resistant group may suggest ongoing seizures cause cellular stress which could increase susceptibility to senescence in drug-resistant pediatric epilepsy patients over time.

Synthesis and Pd(0)-Catalyzed Arylation of Naphthalen-2-yl 5-Bromofuran-2-Carboxylate Derivatives: Anticonvulsant Evaluation via In Vivo and In Silico Studies - A series of naphthalene-2-yl 5-bromofuran-2-carboxylate (5a-5h) was synthesized using a palladium-catalyzed approach. The in vivo experiments and in silico studies were used to assess the anticonvulsant potential of the synthesized library of compounds. We tested the in vivo anticonvulsant activity using the acute 6 Hz model and pentylenetetrazol (PTZ) seizure models, antiepileptic potential of...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.