Epilepsy News

Teen with Epilepsy Dies After Seizure Leads to Cardiac Arrest: ‘There Was No Warning’ - Ellen May Hardwick, 18, went into cardiac arrest following a seizure that occurred with "no warning." Her family is now raising awareness of SUDEP (sudden unexpected death in epilepsy).

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Focal treatment-resistant epilepsy symptoms improved with antiseizure medication - Please provide your email address to receive an email when new articles are posted on . Monthly seizure frequency percentage reduction was 68.73% for the entire study cohort. For those followed up in ...

Understanding epilepsy: Seven ways to respond to an epileptic seizure - At the forefront of epilepsy research and treatment is the University of Alabama at Birmingham Epilepsy Center, a collaborative initiative between the UAB Department of Neurology and UAB Hospital, ...

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

An Analysis of the Response Time to the Push Button in the Epilepsy Monitoring Unit - The National Association of Epilepsy Centers mandates that epilepsy monitoring unit (EMU) patient observers must always be present to minimize risk of patient injury during admissions. To comply with this requirement, our staffing model and workflow were adjusted accordingly. Upon activation of the event button, rather than attending to EMU patients in person, the patient observer responded ver...

Mini-Open Partial Callosotomy in Pediatric Patients - CONCLUSION: Mini-open partial callosotomy is a safe and efficient procedure that minimizes the morbidity associated with a larger approach. It can be performed and taught in conventionally equipped microsurgical neurosurgery units, thus contributing to further emphasize the use of epilepsy surgery also in resource constrained environments.

Assessment of the utility of optically pumped magnetometer magnetoencephalography in preoperative localization of refractory epilepsy: A prospective study - OBJECTIVE: Precise localization of the epileptogenic zone (EZ) is crucial for epilepsy surgery success. Optically pumped magnetometer magnetoencephalography (OPM-MEG) is a promising noninvasive technique requiring rigorous clinical validation.

Dynamic limbic-executive decoupling underpins the reciprocal link between drug-resistant state and depression in temporal lobe epilepsy - OBJECTIVE: Depression is the most common psychiatric comorbidity in temporal lobe epilepsy. It is not merely a psychological reaction to seizures; accumulating evidence supports a bidirectional relationship in which mood dysregulation may also precede drug resistance. Here, we tested whether dynamic limbic-executive integration provides an in vivo circuit-level substrate for this reciprocity.

High-frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development - OBJECTIVE: The development of posttraumatic epilepsy after traumatic brain injury (TBI) is potentially identifiable by measuring biomarkers of epileptogenesis, namely pathological high-frequency oscillations (pHFOs). pHFOs are promising candidates, but it remains uncertain whether they can be detected early after TBI in clinical settings. This study was undertaken to determine the incidence and...

Add-on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss-of-function gamma-aminobutyric acid type A receptor variants - OBJECTIVE: The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss-of-function (LoF) variants in γ-aminobutyric acid type A (GABA(A)) receptor genes. As a positive allosteric modulator of GABA(A) receptors, case reports suggest that vinpocetine can reduce epileptiform activity and seizure frequ...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.