Epilepsy News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

EPILEPSY AWARENESS: Local neurologist explains condition & seizure first aid - COLUMBUS, Ga. (WRBL) — Local experts say epilepsy is not a condition to be afraid of. Piedmont Columbus Regional pediatric neurologist Pierre Fequiere treats patients with epilepsy every day and knows ...

Study: Epilepsy patients benefit from structured 'seizure action plans' - A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status. These ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

High Retention, Seizure-Freedom Rates for Perampanel in Epilepsy - NASHVILLE, Tennessee ―The retention rate for the antiseizure drug perampanel (Eisai Co, Ltd) is more than 70% for adult patients with epilepsy, new research shows. In early results from the PERPRISE ...

Diagnostic accuracy of artificial intelligence models for seizure outcome prediction after epilepsy surgery: A systematic review and meta-analysis - Drug-resistant epilepsy (DRE) affects approximately one-third of individuals with epilepsy. Although surgery offers the best chance of durable seizure freedom in appropriately selected patients, postoperative outcomes remain difficult to predict. Artificial intelligence (AI) has been proposed to improve individualized presurgical prediction, but its diagnostic performance has not been quantitat...

Quality assessment of persian epilepsy mobile applications: A systematic review using uMARS and DISCERN - CONCLUSION: The results showed that Persian-language epilepsy-related apps demonstrated high functionality but limited support for behavior change, engagement, and esthetics. Information quality was generally poor, and none of the evaluated apps were free of charge. These findings highlight the urgent need for developing high-quality, evidence-based epilepsy apps that support comprehensive self...

Effectiveness and safety of brivaracetam in patients with focal epilepsy: A systematic review and meta-analysis - CONCLUSIONS: Adjunctive BRV achieves a pooled responder rate of 44.0%, with results stable on sensitivity analysis. Longer duration of epilepsy may be associated with reduced effectiveness. BRV exhibits an acceptable safety profile, supporting its use as an adjunctive option for focal epilepsy.

Small sharp spikes precede the development of epileptiform discharges in temporal lobe epilepsy - Small sharp spikes (SSS), traditionally regarded as benign EEG variants, have increasingly been linked to temporal lobe epileptogenicity. However, their potential role as early EEG biomarkers of temporal lobe epilepsy (TLE) remains unclear. We analyzed 11 patients with or without a prior epilepsy diagnosis whose initial EEGs demonstrated isolated SSS in the absence of interictal epileptiform di...

Bayesian Uncertainty-aware Deep Learning with noisy labels: Tackling annotation ambiguity in EEG seizure detection - Deep learning is advancing EEG processing for automated epileptic seizure detection and onset zone localization, yet its performance relies heavily on high-quality annotated training data. However, scalp EEG is susceptible to high noise levels, which in turn leads to imprecise annotations of the seizure timing and characteristics. This "label noise" presents a significant challenge in model tra...

Aggression in epilepsy and sleep: from historical accounts to brain networks and human behaviour - For a long time, epilepsy has been associated with violent behaviour, acquiring a highly stigmatising reputation, shaped mainly by 19th-century medical theories that postulated a direct connection between epilepsy and the criminal personality. Such stigma exerts a negative effect on the quality of life of people with epilepsy and remains a significant concern in forensic settings. This narrativ...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.