Epilepsy and Seizure News
Many people have seizures. Here's why it doesn’t always mean epilepsy -
One of the most common causes of epilepsy is a structural brain abnormality. “Epilepsy can result from structural issues in the brain, such as brain tumors, brain injuries, brain infections or ...
Late-Onset Epilepsy a Distinct Neurodegenerative Subtype? -
Emerging clinical and autopsy evidence points to late-onset epilepsy as a potentially distinct, neurodegeneration-related form of epilepsy, with many cases still unexplained.
‘First Seizure Clinic’ for Pediatric Epilepsy a Model of Success -
A dedicated pediatric “one-stop” First Seizure Clinic cuts wait times to under a week and enables earlier diagnoses, giving families faster answers and more streamlined care.
Going beyond seizure control: evidence for cost-effectiveness of epilepsy surgery -
Over 10 million people with epilepsy qualify as surgical candidates worldwide, with 1.4 million new potential surgical candidates added each year.1 The actual number of epilepsy surgeries performed ...
'I just felt like me': West MI woman's journey from epilepsy to seizure-free life -
Taylor Hyma's journey from enduring drug-resistant epilepsy to becoming seizure-free after brain surgery highlights hope and challenges for patients.
AES: First Seizure Clinic Speeds Time to Diagnosis With Pediatric Epilepsy -
Children referred to a first seizure clinic often see a neurologist epilepsy specialist within 1 week for timely diagnosis and treatment.
Supporting someone with epilepsy: How you can help during a seizure | Health Smart -
"First thing is safety. Lower them to the ground, turn them to the side so they don't choke and time the seizure. If it goes beyond 3 to 4 minutes, call 911 immediately and don’t put anything in the ...
AI-powered models ease burden of clinical decision-making in drug-resistant epilepsy -
AI-powered registries may improve epilepsy care by extracting data from incomplete medical records, easing the burden on clinicians when decisions are necessary regarding surgical evaluations, data ...
GLP-1 drugs linked to lower epilepsy risk in diabetes patients -
Research last month suggested that starting GLP-1 receptor agonist treatment in people with epilepsy and type 2 diabetes was associated with reduced risks of seizure recurrence, hospitalization, and ...
Experts warn TikTok epilepsy care videos can be misleading -
Fake clickbait TikTok videos about epilepsy treatments are receiving more views than accurate, evidence-based offerings, a new study says.
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Microscale maps of bursting dynamics across human hippocampal slices from epilepsy patients -
Neuronal firing patterning in the dentate gyrus of epilepsy patients remains unknown at the microcircuit level. Advancements in high-density CMOS-based microelectrode arrays can be harnessed to study network activity with unprecedented spatial and temporal resolution. We use novel computational methods with high-density electrophysiology recordings to spatially map network activity of human hip...
DCPat-XFE: an explainable EEG model for psychogenic nonepileptic seizure detection -
Detecting Psychogenic Nonepileptic Seizures (PNES) is vital because PNES mimics epileptic seizures but has psychological-not electrical-origins, leading to frequent misdiagnosis and ineffective treatment. Electroencephalography (EEG) provides a non-invasive view of brain activity for distinguishing PNES from true epilepsy. Current PNES detection methods remain limited. This study introduces a c...
Impact of High-Dose Tafamidis on Hereditary ATTR (ATTRv) Amyloidosis With Central Nervous System Involvement: Two Case Reports With Clinical, Radiological and Cerebrospinal Fluid Follow Up -
CONCLUSIONS: In our two patients, progression of CNS disease occurred whilst on high-dose tafamidis, highlighting the importance of further studies into the monitoring and treatment of CNS manifestations of ATTRv.
Contextualising multimorbidity in people who use drugs: analysis of drug-death decedents in Scotland -
CONCLUSIONS: Individuals experiencing drug-related deaths exhibit substantial multimorbidity with distinct patterns often dominated by substance use and mental ill-health but also including significant physical health clusters. These distinct profiles underscore the need for integrated, tailored care strategies addressing substance use, psychiatric, and physical health needs to mitigate mortali...
Proteome profiling of cerebrospinal fluid-derived extracellular vesicles reveals potential biomarkers for drug-resistant epilepsy -
CONCLUSIONS: Proteins with differential abundance studied here are associated with epilepsy due to their potential involvement in critical processes such as neuroprotection, inflammation, cell integrity, and immune response. The observed reduction in the abundance of these proteins in drug-resistant dogs suggests that disruptions in these processes may contribute to the severity of the conditio...
Calcium-Activated Potassium Channel KCa3.1 Shape Epileptiform Discharges in the Rodent Entorhinal Cortex -
The mechanisms underlying the generation and termination of epileptic discharges remain incompletely understood. This study investigates the role of K(Ca)3.1 (KCNN4) channels in modulating epileptiform activity in the deep layers of the entorhinal cortex using two in vitro models: short-lasting late recurrent discharges (LRDs) and prolonged tonic-clonic seizure-like events (SLEs). Whole-cell pa...
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