Neurofeedback News
Medical News Today
PubMed
Loss of Function of AFG3L2 Leading to Developmental and Epileptic Encephalopathy -
AIM: To delineate the clinical features of AFG3L2-related developmental and epileptic encephalopathy (DEE) and explore its pathogenic mechanisms.
Epileptogenic lesions in the Australian epilepsy project: A harmonized 3-T magnetic resonance imaging protocol and its diagnostic yield -
OBJECTIVE: Detection of epilepsy-causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, prognosis, and treatment planning in people with epilepsy. We aimed to establish an epilepsy-directed multisite harmonized 3-T MRI acquisition protocol for the Australian Epilepsy Project (AEP) and describe the clinical structural brain findings in the initial partici...
Risk Factors for White Matter Lesion Burden in Adults with Focal Epilepsy -
CONCLUSION: WMH are common in adults with focal epilepsy, and the frontal lobe is the most frequently affected region. Age, interictal epileptiform discharges, and seizure duration are independent risk factors for greater WMH burden. WMH may serve as an imaging marker for clinical seizure severity.
Antiseizure Medications Impact Mitochondrial Ion Channels via Novel Bioenergetic and Neural Mechanisms -
Antiseizure medications (ASMs) have traditionally been characterized by their modulation of neuronal ion channels and synaptic processes; however, accumulating evidence indicates that numerous ASMs also directly modulate mitochondrial function. Specifically, several ASMs interact with ion channels located in both the inner and outer mitochondrial membranes, including the voltage-dependent anion...
Shoulder instability and associated shoulder injuries in patients with epilepsy -
CONCLUSION: In patients with epilepsy, shoulder dislocations predominantly occur during generalized seizures, with anteroinferior dislocations being the most frequent, while posterior dislocations are significantly more prevalent compared to the general population. Recurrent dislocations were associated with significantly larger humeral and posterior glenoid defects, indicating progressive bone...
Effect of immunotherapy on seizure severity and spike-wave index in epileptic encephalopathy with spike-wave activation in sleep: The value of EEG spikes in monitoring treatment response -
CONCLUSION: IVIg therapy was associated with significant and sustained electrophysiological improvement and is accompanied by clinical improvement in children with EE-SWAS and DEE-SWAS. However, changes in SWI were not significantly correlated with functional, behavioral, or seizure outcomes, suggesting a dissociation between electrophysiological and clinical responses. These findings indicate ...
Science Daily