Phenobarbital monotherapy for convulsive seizures in rural Northwest China: a 12-year longitudinal study -
CONCLUSIONS: Our study demonstrated that convulsive seizures could be effectively controlled with PB monotherapy with mild adverse effects in rural areas in Northwest China. Early treatment response, particularly seizure freedom within the first two years, is a strong indicator of long-term remission. High baseline seizure frequency is an independent risk factor for poor prognosis.
Neurofilament light-chain (Nf-L) as a biomarker in seizures and status epilepticus of varying duration -
CONCLUSION: Our data indicate that single and acute repetitive seizures likely do not cause significant neuronal injury as assessed by Nf-L concentrations in serum and CSF. In contrast, status epilepticus is accompanied by a duration-dependent increase in serum Nf-L, which presumably reflects seizure-associated cellular injury and underlines the need for rapid and consistent antiseizure treatment.
Stigma as social comorbidity in epilepsy -
Empirical evidence confirms both the pervasiveness and the significant impact of stigma among people with epilepsy (PWE). Despite being one of the most extensively studied neurological disorders, epilepsy continues to carry a disproportionate social burden across cultures and historical periods. Stigma is not only a psychological consequence but also a chronic social determinant of health that ...
Science Daily
Brain signal irregularity may provide clues to understanding epileptic process -
Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.
Breakthrough tech enables seizure localization in minutes -
New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.
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