Epilepsy News

Every seizure can look and feel very different: NMU holds presentation on epilepsy and seizure training - The presentation hopes to clear up misconceptions regarding epilepsy and seizures as well as how to help those in need.

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Development and psychometric validation of a screening tool of psychosocial risk factors in patients with epilepsy: the ARisE study protocol - Introduction Epilepsy is one of the most common neurological chronic diseases worldwide. While medications can control seizures, about one-third of people with epilepsy have drug-resistant epilepsy ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Michigan Epilepsy Foundation to host seizure recognition training - On Wednesday’s TV6 Morning News, Shannon Waid and Renee Roederer with the Michigan Epilepsy Foundation joined Molly Birch to explain how you can participate.

First seizure clinic provides visit, pediatric epilepsy diagnosis in less than a week - Please provide your email address to receive an email when new articles are posted on . The model expedites access to specialists after a first seizure. The mean time between the referral and the ...

In people with epilepsy, sleeping after a seizure may trigger more seizures - Add Yahoo as a preferred source to see more of our stories on Google. A new study suggests that the memory-forming stage of sleep could be key for understanding epileptic seizures. . | Credit: ...

Does Levetiracetam Improve Seizure Outcomes in Pediatric Epilepsy? - Although levetiracetam was associated with improved seizure outcomes compared with placebo in pediatric epilepsy, it did not demonstrate superior efficacy when compared with established active ...

Voxel-based morphometry in mesial temporal lobe epilepsy surgery: an exploratory Moroccan pilot study - CONCLUSION: Implementing this VBM workflow was feasible within a newly established Moroccan epilepsy surgery programme. The findings are preliminary, descriptive, and hypothesis-generating; they do not establish disease mechanisms or postoperative reorganization. Larger, adequately powered longitudinal studies using dedicated repeated-measures models and multimodal quantitative MRI are required.

Reduced inhibition of hippocampal adult-born granule cells by parvalbumin interneurons after TBI - Traumatic brain injury (TBI) is one of the leading causes of acquired temporal lobe epilepsy. TBI drives hippocampal circuit rearrangements that may contribute to increased seizure risk, such as altered inhibitory circuit function and aberrant post-traumatic neurogenesis. In the hippocampal dentate gyrus, adult-born dentate granule cells (DGCs) acquire inhibitory synaptic inputs from parvalbumi...

Parvalbumin interneurons and dentate gyrus homeostatic dysregulation shape epileptogenesis in Angelman syndrome model mice - Understanding how neural circuits transition from seizure-resistant to seizure-prone is essential for developing improved epilepsy therapies. Here, we study this process by leveraging the heightened susceptibility to seizure kindling of Angelman syndrome (AS) model mice, which lack the maternal Ube3a (mUbe3a) allele. We identify parvalbumin-expressing (PV+) interneurons as critical gatekeepers;...

Perampanel improves cognitive function in epilepsy by targeting AMPA receptor subunit GluR2-mediated endoplasmic reticulum stress and synaptic plasticity - CONCLUSION: GluR2-mediated ERS may involve the improved effects of Perampanel in cognitive function of epilepsy patients by promoting synaptic plasticity.

mTORC1 drives cell-autonomous astrocyte reactivity in tuberous sclerosis - Tuberous sclerosis complex (TSC) is a genetic neurodevelopmental disorder characterized by focal brain malformations called cortical tubers, which are associated with severe, intractable epilepsy¹. Tubers are thought to result from somatic second-hit mutations that disrupt the TSC1 or TSC2 genes in neural progenitor cells, driving hyperactive mTORC1 signalling². Glial abnormalities are commonly...

Development and psychometric validation of a screening tool of psychosocial risk factors in patients with epilepsy: the ARisE study protocol - INTRODUCTION: Epilepsy is one of the most common neurological chronic diseases worldwide. While medications can control seizures, about one-third of people with epilepsy have drug-resistant epilepsy and continue to experience seizures. Psychosocial burdens are a major concern, as they are linked to seizure worsening and vice versa. Early identification of risk factors for psychosocial burdens c...

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.