Epilepsy News

Recent news about epilepsy, seizures and treatments.

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Epilepsy and Seizure News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Using Seizure-Risk Forecasts to ID Best Time for Epilepsy Monitoring - NASHVILLE, Tennessee ― Scheduling video-electroencephalography (vEEG) monitoring on the basis of personalized seizure risk forecasts may improve diagnostic accuracy, emerging research suggests. In a ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

In people with epilepsy, sleeping after a seizure may trigger more seizures - Add Yahoo as a preferred source to see more of our stories on Google. A new study suggests that the memory-forming stage of sleep could be key for understanding epileptic seizures. . | Credit: ...

Decoding epilepsy in brain waves - Neurologists often use EEGs to help diagnose epilepsy, but routine recordings offer only about a 20-minute snapshot of brain activity. Without a seizure captured during that window, clinicians must ...

Medical News Today

PubMed

Abnormal KCC2 expression and function in a mouse model of epilepsy and tuberous sclerosis complex - OBJECTIVE: Drug-resistant epilepsy is a common, severe manifestation of the genetic disorder tuberous sclerosis complex (TSC). Although significant mechanistic and therapeutic advances have been made in TSC, treatments for seizures remain largely ineffective. Decreased expression of the potassium-chloride cotransporter KCC2 is associated with depolarizing γ-aminobutyric acid (GABA) signaling an...

The genetic architecture of epilepsy across molecular mechanisms and clinical heterogeneity - Epilepsy comprises a highly heterogeneous group of neurological disorders unified by a persistent predisposition to recurrent seizures, yet driven by remarkably diverse genetic, molecular, and network-level mechanisms. Advances in genomic technologies have revealed that epilepsy arises from a multilayered genetic architecture encompassing rare high-penetrance monogenic variants, common polygeni...

Auditory-triggered reflex focal motor seizures after stroke: A video-EEG case - No abstract

MRI-targeted focal transcranial magnetic stimulation reproducing habitual seizure semiology during presurgical evaluation: An instructive clinical vignette - No abstract

Efficacy of synthetic ACTH in confirmed and presumed monogenic developmental and epileptic encephalopathies - OBJECTIVE: Adrenocorticotropic hormone (ACTH) is an effective treatment for infantile epileptic spasms syndrome (IESS); however, its mechanism of action remains incompletely understood. This study aimed to evaluate ACTH treatment response at the level of protein-protein interactions (PPIs) in patients with confirmed and presumed monogenic developmental and epileptic encephalopathies (DEEs).

Nucleus basalis functional connectivity aberrations in temporal lobe epilepsy and improvements after successful epilepsy surgery - OBJECTIVE: Resective surgery achieves seizure freedom in approximately 60%-80% of patients with drug-resistant temporal lobe epilepsy (TLE), yet the extent to which seizure cessation permits recovery of disrupted functional brain networks remains unclear. Increasing evidence suggests that recurrent seizures alter subcortical-cortical communication involved in arousal and cognition, contributing...

Science Daily

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.

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