Epilepsy and Seizure News
Epilepsy can lead to earlier deaths in people with intellectual disabilities, study shows -
A combination of missed prevention opportunities and health inequalities can result in the early deaths of people living with epilepsy and intellectual disabilities, a study has shown.
GLP-1 diabetes drugs linked to lower epilepsy risk in large study -
A preliminary study of people with diabetes suggests that use of glucose-lowering GLP-1 drugs may be linked to a lower risk of developing epilepsy. The study was published in Neurology.
Promising Long-Term Results for Novel Antiseizure Medication for Resistant Epilepsy -
A novel Kv7 potassium channel opener, may offer a unique treatment option for patients with resistant focal onset seizures.
Experts warn TikTok epilepsy care videos can be misleading -
Fake clickbait TikTok videos about epilepsy treatments are receiving more views than accurate, evidence-based offerings, a new study says.
Praxis claims efficacy success in phase 2 seizure trial, setting up approval talks with FDA -
“SCN2A and SCN8A DEEs are devastating conditions with extremely high mortality due to the debilitating seizure burden they impose on patients, and there are currently no approved treatment options,” ...
Supporting someone with epilepsy: How you can help during a seizure | Health Smart -
"First thing is safety. Lower them to the ground, turn them to the side so they don't choke and time the seizure. If it goes beyond 3 to 4 minutes, call 911 immediately and don’t put anything in the ...
Semaglutide Tied to 50% Lower Risk for Epilepsy in Diabetes -
Semaglutide, a GLP-1 receptor agonist (RA), was associated with a significantly lower risk for adult-onset epilepsy in patients with diabetes than other glucose-lowering drugs (GLDs). Notably, this ...
Ozempic Shows a Possible Hidden Effect on Epilepsy Risk -
Popular GLP-1 medications such as Ozempic may carry an unexpected link to a lower risk of epilepsy in people with type 2 diabetes.
Stricter approval process reduces prescribing of anti-seizure drug that can cause birth defects -
The introduction of a stricter approval process for prescribing an anti-seizure drug that can cause birth defects when taken during pregnancy has been effective at reducing the number of prescriptions ...
Seizure-free childhood epilepsy could lead to suboptimal social, educational outcomes in young adults -
Learning difficulties and behavioral problems during childhood can lead to suboptimal social and educational outcomes among young adults with childhood epilepsy even when their seizures are well under ...
Medical News Today
PubMed
Association Between GLP-1 Receptor Agonist Use and Epilepsy Risk in Type 2 Diabetes -
BACKGROUND AND OBJECTIVES: Individuals with type 2 diabetes mellitus (T2DM) are at an increased risk of developing epilepsy, particularly in later life. While preclinical studies suggest neuroprotective properties of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), real-world comparative effectiveness data remain limited. We aimed to evaluate whether GLP-1 RA use is associated with a lowe...
Management of Functional Seizures Practice Guideline Executive Summary: Report of the AAN Guidelines Subcommittee -
This guideline provides evidence-based recommendations for clinicians, patients, and other stakeholders on the management of functional seizures. Following a National Academy of Medicine-compliant process, a multidisciplinary panel conducted a systematic review and integrated the findings with the authors' clinical experience to develop recommendations. A systematic review of the available evid...
Teaching Video NeuroImage: Tapping-Triggered Seizure Secondary to Focal Cortical Dysplasia in the Primary Somatosensory Cortex -
No abstract
Effect of Anti-Seizure Medications on Interictal Epileptiform Discharges in Focal Epilepsy -
The purpose of this study was to assess the change in frequency and distribution of focal interictal epileptiform discharges (IEDs) as measured on scalp EEG after anti-seizure medications (ASMs) were weaned in the epilepsy monitoring unit. We retrospectively reviewed the EEG of patients with focal epilepsy on a single ASM. A two-hour EEG epoch was selected at sleep onset during the first day of...
Altered Glut4, IRAP, and Brain Insulin Signaling in a Mouse Model of Epilepsy and Contributions to Glucose Transport in Neurons and Astrocytes -
There is evidence that glucose transport is impaired between seizures, which can promote seizure generation. In addition to glucose transporters Glut1 and Glut3, Glut4 is also found in the brain. Glut4 translocation is regulated by insulin signaling in peripheral tissues and insulin-regulated aminopeptidase (IRAP), but remains poorly understood in the brain. This study aimed to characterize the...
Type 3 Sturge-Weber Syndrome Presenting With Concurrent Epilepsy and Migraine -
Sturge-Weber syndrome is a rare congenital disorder with vascular malformations affecting the brain, skin, and eyes. Type 3 Sturge-Weber syndrome, the rarest form, presents with isolated leptomeningeal angiomas, often causing diagnostic delays. This report highlights an unusual presentation where both recurrent focal seizures and migraine-like headaches were prominent, long-standing features. A...
Science Daily