Epilepsy and Seizure News
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Role of antiseizure medication in postoperative late seizure and survival among patients with newly diagnosed glioblastoma: A multicenter retrospective study -
CONCLUSIONS: LEV and PER after glioblastoma surgery were associated with a reduced risk of late seizure compared with LCM or no medication. LEV or PER may be considered as postoperative ASMs to optimize seizure control and potentially help preserve patients' QOL.
Hemispheric asymmetries in rodent models of neurological diseases: a systematic review -
INTRODUCTION: Hemispheric asymmetries are a core organizational principle of the vertebrate brain, but they are still not fully integrated into the study of preclinical models of neurological disease. Although many rodent models naturally include lateralization through unilateral interventions, hemispheric differences are not consistently examined or systematically reported.
Pediatric occipital lobe epilepsy: A modern review of etiological classification, management, and outcomes -
Pediatric occipital lobe epilepsy (OLE) comprises syndromes with seizures originating from the posterior cerebral cortex. Previously "benign", recent International League Against Epilepsy (ILAE) updates reclassified these as self-limited or structural focal epilepsies, reflecting their complex causes and morbidity potential. The 2017 ILAE guidelines shifted from syndromic recognition to an etio...
Successful Treatment of Refractory Landau-Kleffner Syndrome with Memantine in a Child with GRIN2A Gain-of-Function Variant -
Landau-Kleffner syndrome and related epilepsy-aphasia spectrum disorders are characterized by childhood-onset language regression, sleep-activated epileptiform activity, and frequently refractory seizures. This case report describe a boy with normal early development who developed progressive aphasia and non-motor seizures around age three, with electroencephalographic findings consistent with ...
New-Onset Convulsive Status Epilepticus Temporally Associated With Accidental Inhalation of Billygoat Weed (Ageratum conyzoides) Smoke: A Case Report -
Status epilepticus is most commonly associated with structural, metabolic, infectious, autoimmune, or toxic etiologies. Plant-related toxic exposures are uncommon causes of new-onset status epilepticus and remain poorly characterized. Ageratum conyzoides (billygoat weed) is an invasive plant widely distributed in tropical and subtropical regions and is frequently used in traditional medicine. W...
DECREASE study: A European pool-analysis of patients with significant reductions in concomitant antiseizure medications in cenobamate Early Access Programs -
OBJECTIVE: To evaluate the effectiveness and tolerability of cenobamate in patients with a significant reduction in concomitant antiseizure medication (ASM) in European cenobamate Early Access Programs (EAPs).
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