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Clinical significance of subclinical seizures in epilepsy presurgical evaluation: A systematic review and meta-analysis -
OBJECTIVE: Subclinical seizures (SCSs) remain an understudied aspect of presurgical evaluation in patients with drug-resistant epilepsy (DRE), with uncertain prevalence, distribution among epilepsy types, and predictive value for surgical outcomes. This systematic review and meta-analysis aims to explore the occurrence of SCSs, their concordance with the seizure-onset zone (SOZ), and their asso...
Clinical subtypes and sleep-wake evolution pattern in epilepsy manifesting as sleep-related seizures -
OBJECTIVE: Epilepsy manifesting as sleep-related seizures (EpSRS) represents a common but heterogeneous group. This study aimed to identify distinct clinical subtypes of EpSRS and explore alterations in sleep-wake seizure rhythms over the disease course.
Seizure Action Plans Beyond the Neurology Clinic: What Emergency, School, and Primary Care Teams Need to Know for Children With Epilepsy -
Most seizures in children with epilepsy occur outside the neurology clinic. Seizure action plans (SAPs) are designed to extend the neurologist's management plan into these settings. Early SAPs primarily targeted caregivers, while current plans target not only caregivers but also teachers, other medical providers, and anyone else who may be able to intervene on behalf of these children. Some stu...
Recurrence rate and risk factors of recurrence after antiseizure medications withdrawal in children with epilepsy: a meta-analysis -
CONCLUSION: Multiple factors increase recurrence risk after antiseizure medications withdrawal in children, supporting individualized clinical decision-making.
Bridging the Gap Between Depression and Epilepsy: A Call for Integrated Neuropsychiatric Care -
"Brain health" encompasses key functions such as cognition, emotion, and behaviour, and is increasingly relevant given its role across neurological and psychiatric conditions. One of these, depression is the most common psychiatric comorbidity in people with epilepsy (PWE). When unrecognized and untreated, depression is associated with increased seizure severity and poorer treatment response, s...
Pathological and Physiological Significance of Hippocampal Ripples in Epilepsy -
Ripple activity is defined as a high-frequency synchronous neural activity that has emerged as an important biomarker of epilepsy, both in research and clinical practice. In intracranial electroencephalography, ripple-band activity is closely linked to epileptogenicity and has been investigated as a marker to guide localization of epileptogenic tissue and predict surgical outcomes. Simultaneous...
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