Epilepsy News

Seizure action plans: Management and educational tools in epilepsy care - Historically, seizure action plans have focused on certain high-risk groups—such as people with drug-resistant epilepsy and people with a history of status epilepticus or seizure clusters. Neurology ...

Study: Epilepsy patients benefit from structured 'seizure action plans' - A new 16-week study of 204 adult epilepsy patients found that 98% of participants believe that all patients with epilepsy should have a seizure action plan (SAP), regardless of seizure status. These ...

Epilepsy: Understanding Seizures, Saving Lives, And Protecting Future Generations - Epilepsy is not a curse, not a mental illness, not contagious. It is a medical condition deserving compassion. Across societies, countless individuals living with epilepsy continue to endure fear, ...

EPILEPSY AWARENESS: Local neurologist explains condition & seizure first aid - COLUMBUS, Ga. (WRBL) — Local experts say epilepsy is not a condition to be afraid of. Piedmont Columbus Regional pediatric neurologist Pierre Fequiere treats patients with epilepsy every day and knows ...

Seizure Burden in Resistant Epilepsy May Ease With the Tincture of Time - Nearly 70% of patients with focal treatment-resistant epilepsy (FTRE) experience fewer seizures over time, new results of a multicenter study showed. However, the improvements occurred independent of ...

Rethinking cortical hypertrophy in temporal lobe epilepsy - Epilepsy is one of the most common chronic neurological disorders, and temporal lobe epilepsy (TLE) is its most prevalent form in adults. Although TLE is classified as a focal epilepsy, it has traditionally been defined by hippocampal and extra-hippocampal atrophy. However, several studies also report regions of increased cortical thickness, or cortical hypertrophy, in TLE, challenging the noti...

Minute-Resolution Sampling Reveals Rapid and Stimulus-Specific IL-1β Dynamics During Acute Epileptiform Activity - Brain inflammation is increasingly recognized as a critical contributor to seizure generation and neuronal hyperexcitability. Among proinflammatory mediators, interleukin-1β (IL-1β) has been implicated in epileptogenesis; however, its acute temporal dynamics during seizure initiation remain poorly characterized because of limitations in conventional sampling approaches. In this study, we invest...

Complete seizure freedom following minimally invasive laser callosotomy in a patient with lissencephaly type 1: Challenging the traditional paradigm - No abstract

Cerebral X-Linked Adrenoleukodystrophy Associated with Hemophilia A: a case report - CONCLUSIONS: This case highlights the genetic vulnerability of the Xq28 locus and the possible co-occurrence of Hemophilia A and ALD. Physicians should maintain a high index of clinical suspicion for ALD in males with known FVIII deficiency and cognitive signs or concomitant hyperpigmentation as early diagnosis is vital for life-saving therapeutic interventions.

Predictors of long-term seizure outcomes and perceived quality of life outcomes after temporal lobe epilepsy surgery - CONCLUSIONS: TLE surgery provides robust seizure control and significant perceived QOL improvements for most patients in the long term. Hippocampal sparing surgery in NTLE did not seem to affect perceived memory difficulties but was more likely to be associated with suboptimal seizure outcomes.

Lacosamide Concentration in Various Biological Matrices (Plasma, Saliva, and Hair) Does Not Correlate with Clinical Outcomes in Patients with Epilepsy - CONCLUSIONS: Lacosamide concentrations in blood, saliva, or hair do not correlate with seizure frequency and are therefore not reliable markers of adherence. However, salivary lacosamide measurement may offer a practical alternative to plasma monitoring.

Brain signal irregularity may provide clues to understanding epileptic process - Researchers propose a new method to differentiate signals from the epileptic focus from those recorded in other parts of the brain without the presence of an epileptic seizure. This technique may help detect epilepsy-induced features from these signals much quicker than conventional analysis techniques.

Breakthrough tech enables seizure localization in minutes - New research introduces a novel network analysis technology that uses minimally invasive resting state electrophysiological recordings to localize seizure onset brain regions and predict seizure outcomes in just 10 minutes.

Antidepressant use during pregnancy not linked to epilepsy in children - A new study suggests that antidepressant use by mothers during the first trimester of pregnancy does not increase the chances of epilepsy and seizures in babies.