My husband and I are about at our wits end with epilepsy meds for our 19 year old son with autism and epilepsy. He has been on trileptal for 5 years and tolerated it well, but he still has about 2 to 3 seizures a month. In the past 15 months we have tried Vimpat, Depakote and Topamax. All gave him horrible side effects.He was aggressive, agitated and had rashes sometimes. We tried lamictal for about 6 months and it increased his seizures and his behavior was always so on and off. So now we are back to just trileptal. It seems every med we try is just a disaster. He is also taking a long time to withdraw from lamictal, he has good days and bad days. 15 months ago we didn't have any aggressive behaviors. We feel the constant going on and off meds has really messed him up. Which is worse , a seizure or freaking out from medication? I vote for freaking out from meds. Just wondering if anyone else hears about people with autism having difficulty with meds!