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Seizures are known manifestation of hypoglycemia. In patients with epilepsy, hypoglycemia might decrease the threshold for seizure development. In one study of 92 patients with epilepsy, 56.4% were found to have a subnormal fasting blood glucose concentration.
In addition, transient EEG abnormalities have been observed in some patients during a glucose tolerance test. These abnormalities occurred, not when the blood glucose level was at its lowest point, but at a time that insulin levels would have been expected to be elevated. These EEG changes werre hypothesized to result from insulin-induced transport of water and electrolytes into the brain, leading to cerebral hyperosmolality. While the observed EEG changes were not necessarily of the type associated with seizures, these finding raise the possibility that hyperinsulinemia could trigger seizures in patients with epilepsy.
Thus, hypoglycemia and hyperinsulinemia might each contribute to the pathogenesis of epilepsy in some cases. Patients with epilepsy who have evidence of these abnormalities might benefit from nutritional interventions, such as avoiding refined sugar, caffeine, and alcohol; eating frequently; consuming adequate amounts of protein, and supplementing with chromium, other trace minerals, magnesium, and B vitamins.
http://findarticles.com/p/articles/mi_m0FDN/is_1_12/ai_n19170695/