http://www.drugs.com/drug_interactions.phpInteractions between your selected drugs
No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.
Other drugs that your selected drugs interact with
• There are 137 other drugs known to interact with 5-HTP (5-hydroxytryptophan)
• There are 818 other drugs known to interact with Topamax (topiramate)
http://en.wikipedia.org/wiki/Serotonindream more vividly - wake up with tons of energy (that's a new one for me!)
Tryptophan is thought to be only a dietary factor when it's well known to be made by microbes such as bacteria and yeast via biosynthesis. When in balance, I believe our gut flora likely has the enzymes necessary to create tryptophan. There's a lot of research since the 1960s on E.coli producing tryptophan, yet I can't seem to find anything about gut flora producing our tryptophan (it's all about eating turkey and cashews to modern science).The Wikipedia has some good info on 5 HTP, serotonin and melatonin. Basically, the body uses 5-HTP to create serotonin in the brain. Serotonin is used to produce melatonin. The advantage of taking 5-HTP versus the end products directly (via the digestive tract) is that the end products cannot pass through the blood-brain barrier, so they are less effective:
Here's another page that lays it all out:From Tryptophan to Serotonin to Melatonin