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A 2008 critical review found that with the possible exception of back pain, chiropractic manipulation has not been shown to be effective for any medical condition.[16] Health claims made by chiropractors regarding use of manipulation for pediatric health conditions are supported by only low levels of scientific evidence[105][131] that does not demonstrate clinically relevant benefits.[132]
A 2012 systematic review found insufficient low bias evidence to support the use of spinal manipulation as a therapy for the treatment of hypertension.[157] A systematic review in 2011 found moderate evidence to support the use of manual therapy for cervicogenic dizziness.[158] There is very weak evidence for chiropractic care for adult scoliosis (curved or rotated spine)[159] and no scientific data for idiopathic adolescent scoliosis.[160] A 2007 systematic review found that few studies of chiropractic care for nonmusculoskeletal conditions are available, and they are typically not of high quality; it also found that the entire clinical encounter of chiropractic care (as opposed to just SM) provides benefit to patients with cervicogenic dizziness, and that the evidence from reviews is negative, or too weak to draw conclusions, for a wide variety of other nonmusculoskeletal conditions, including ADHD/learning disabilities, dizziness, high blood pressure, and vision conditions.[161] Other reviews have found no evidence of significant benefit for asthma,[162] baby colic,[131][163] bedwetting,[164] carpal tunnel syndrome,[165] fibromyalgia,[166] gastrointestinal disorders,[167] kinetic imbalance due to suboccipital strain (KISS) in infants,[131][168] menstrual cramps,[169] or pelvic and back pain during pregnancy.[170]