[Info] Drugs that deplete the body of Magnesium

[RobinN]

Drug Muggers of Magnesium

Acid Blockers

* Cimetidine (Tagamet)
* Esomeprazole (Nexium)
* Famotidine (Pepcid and Pepcid Complete)
* Nizatidine (Axid)
* Omeprazole (Prilosec OTC)
* Pantoprazole (Protonix)
* Ranitidine (Zantac)
* Rabeprazole (Aciphex)
* Ranitidine (Zantac)

Antacids

* Aluminum and magnesium hydroxide (Maalox, Mylanta)
* Aluminum carbonate gel (Basaljel)
* Aluminum hydroxide (Amphojel, AlternaGEL)
* Calcium carbonate (Tums, Titralac, Rolaids)
* Magnesium hydroxide (Phillips’ Milk of Magnesia)
* Sodium bicarbonate (Alka-Seltzer, baking soda)

Antibiotics (a few examples)

* Amoxicillin (Amoxil)
* Azithromycin (Z-Pak)
* Cefaclor (Ceclor)
* Cefdinir (Omnicef)
* Cephalexin (Keflex)
* Ciprofloxacin (Cipro)
* Clarithromycin (Biaxin)
* Doxycycline (Doryx)
* Erythromycin (E.E.S.)
* Levofloxacin (Levaquin)
* Minocycline (Minocin)
* Sulfamethoxazole and trimethoprim (Bactrim, Septra)
* Tetracycline (Sumycin)

Antiviral Agents

* Delavirdine (Rescriptor)
* Foscarnet (Foscavir)
* Lamivudine (Epivir)
* Nevirapine (Viramune)
* Zidovudine, AZT (Retrovir)
* Zidovudine and Lamivudine (Combivir)

Blood Pressure Drugs

* Hydralazine (Apresoline)

ACE inhibitors:

* Enalapril and HCTZ (Vaseretic)

Angiotensin II receptor blockers:

* Valsartan and HCTZ (Diovan HCT)

Diuretics, loop:

* Bumetanide (Bumex)
* Ethacrynic acid (Edecrin)
* Furosemide (Lasix)
* Torsemide (Demadex)

Diuretics, thiazide (and any combination drug that contains HCTZ or hydrochlorothiazide—dozens of drugs contain this)

* Candesartan and HCTZ (Atacand HCT)
* Chlorothiazide (Diuril)
* Chlorthalidone (Hygroton)
* Hydrochlorothiazide or HCTZ (Hydrodiuril)
* Methyclothiazide (Enduron)
* Metolazone (Zaroxolyn)

Diuretics, potassium-sparing:

* Possibly the potassium-sparing diuretics, however this is not conclusive

Diuretics, sulfonamide:

* Indapamide (Lozol)
* Cardiac Glycoside
* Digoxin (Digitek, Lanoxicaps, Lanoxin)

Central Nervous System (CNS) Stimulants

* Methylphenidate (Metadate, Ritalin)

Cholesterol Agents

* Cholestyramine (Questran)
* Colestipol (Colestid)

Corticosteroids

* Betamethasone (Diprolene, Luxiq)
* Dexamethasone (Decadron)
* Hydrocortisone (Cortef)
* Methylprednisolone (Medrol)
* Mometasone (Elocon)
* Prednisolone (Pediapred Liquid)
* Prednisone (Deltasone, Liquid Pred, Sterapred)
* Triamcinolone (Aristocort cream)

Inhaled corticosteroids:

* Flunisolide (Nasarel, Nasalide)
* Futicasone (Flonase)
* Triamcinolone (Azmacort inhaler)

Hormone Replacement Therapy / Oral Contraceptives

* Diethylstilbestrol (DES)
* Estradiol (Activella, Climara, Combipatch, Estrace, Estraderm, Estring, EstroGel, Femring, Menostar, and many others)
* Estrogen-containing drugs (hormone replacement therapy and birth control)
* Estrogens, conjugated (Premphase, Prempro)
* Estrogens, esterified (Estratab)
* Estropipate (Ogen)
* Ethinyl estradiol (found in many birth control pills)
* Levonorgstrel (found in many birth control pills)

Immunosuppressants

* Cyclosporine (Sandimmune, Neoral)
* Tacrolimus (Prograf)

Nonsteroidal Aromatase Inhibitors for breast cancer

* Anastrozole (Arimidex)

Osteoporosis

* Raloxifene (Evista)

SERMs (Selective Estrogen Receptor Modulators—used for breast cancer)

* Raloxifene (Evista)
* Tamoxifen (Nolvadex)
* Toremifene (Fareston)

Sulfonamides

* Sulfa antibiotics, some diabetic medications

MISC:

* Alcohol
* Calcium supplementation (prolonged or in excess)
* Coffee
* Estrogen dominance
* High cortisol levels
* High-sugar diet (glucose, fructose, sucrose)
* Malabsorption of any sort (celiac or Crohn’s disease, pancreatitis, crash dieting, anorexia)
* Mineral oil

 

[k2s4ever]

I just came across this as I don't go over to this part of the forum as much. Glad I did. This is very interesting, and in a cursory search (very abbreviated), I did see references to magnesium and reducing seizures, or people reporting a correlation in their own experience.
I happen to get bad leg/foot/toe muscle cramps and have been taking a potassium supplement daily for months, and I have seen a reduction, but lately have been having them about once a week, though not as severe and they went away faster. I would wake up and not be able to lie back down as it was so darn painful. It should have dawned on me that other electrolyte issues could be at play. When I was medically hospitalized several years ago for an entirely separate issue, I was running a low potassium and was given it IV. I also though wasn't allowed to eat or drink for days due to how ill I was, but still-there obviously is a tendency there.
Well, I also have GERD and take an RX of omeprazole (less expensive that OTC!) and sure enough-it's on this list of magnesium depleters! I am going to add a magnesium supplement now, and heck, if it has an added benefit toward E, here here! All the better. What's to lose by adding it!
Thanks Robin!!

 

[Nakamova]

I've found that magnesium has helped lower my blood pressure, which zoomed up when i started on Lamictal. You're right that it get helps with muscle cramps of all kinds, including menstrual cramps.

 

[k2s4ever]

Nakamova-what type of magnesium do you take? I read for example that citrate or malate vs. the oxide (which is everywhere) is the better type to get. Well, I went to Target and two pharmacy chains (one supposedly at least had magnesium citrate, figured that might be better even-but nope, none). The vitamin store in my town would have it but was closed, so I just went with plain old oxide vs. having none. Bottle cost me 3 bucks and small change at Target, so figured oh well-just wing it for now.
hopefully it will help anyway.

 

[Nakamova]

I take Thorne brand magnesium, which I order online from iherb.com (it's probably available elsewhere too). They're 140mg magnesium citrate capsules. The "suggested use" is one to three capsules per day. I just take one capsule in the morning with my breakfast, and that certainly seems to do the trick for my blood pressure without any apparent side effects.

 

[k2s4ever]

Thanks. And I looked online and sure enough, the vitamin store has plenty of the citrate, and they stock the physical store with everything-so after I use the oxide, I know where to head. Been in there before, so I know I'll get it next time.