I was on 90mg duloxetine and taking ibuprofen for lower back and knee pain. I walk daily 3000 steps. Help walk our 2 dogs. I was having various GI issues. Saw my PCP. My BP was 178/102. I have hypertension and have been on lisinpril for 10 years. A new article JAMA neurology June 2024 sited ARB blood pressure meds reduce epilepsy incidence. So I stopped all NSAIDS. My duloxetine dose was decreased to 30mg daily. I was given a prescription for losartan 25mg daily. It is the ARB mentioned in the research article. I re started tai chi - somatic tai chi for stress reduction. I have done well in the past when de prescribing is part of my treatment plan.