So what's the "truth" about Zinc and seizures?

[forward2007]

Has anyone ever heard anything from their Neurologist about Zinc and seizures?

They can't seem to make up their mind here:

Zinc and Epilepsy: A Puzzling Relationship

Ever since the discovery that zinc induces seizures in rats, it has resulted in the suggestion that the release of cellular zinc plays a major role in the generation and propagation of epileptic activity. However, as the evidence was gathered, many contradictions accumulated. It has been proposed that zinc may act to attenuate the GABA response and thereby elicit hyperexcitability of the neurons and thereby incur a seizure. Conversely, it has also been found that zinc may act as an inhibitory neurotransmitter decreasing the likelihood of a seizure. Some researchers have noted a post-seizure increase in the level of zinc in the brains of rats and mice while others research do not show an increase. These variations could be due to differing lag times between the seizure and the sacrifice. Zinc has also been implicated in the pathology of cell death in response to activation of glutamate receptors. All in all, there seems to be a connection between zinc and seizures, but there are too many contradictions to clarify the nature of the relationship

 

[epileric]

I've never heard of zinc having any effect on seizures at all. Even from what I've seen in the science sites there doesn't seem to be any definite reaction one way or the other.

CONCLUSIONS:
Clinical research in epilepsy presented contradictory results. In fact, the reviewed studies, both animal and human, did not give enough evidence to determine if organic zinc variations are directly related to epilepsy. Most of them gave not statistically significant results.

http://www.ncbi.nlm.nih.gov/pubmed/16775802

 

[jyearta]

I had problems with taking zinc, but with this memory I can not remember what my reaction was. I did stop using it.

I have since started a log on each medic. presc. and over the counter.
date I started New Med/vit.
date I stopped
reason

 

[Nakamova]

Like all trace elements, zinc plays a role in neurological development, and some studies have a suggested a link between zinc and fever seizures.

But for the most part, as Forward reports, the current zinc research is contradictory and hasn't yet produced definitive info.