Billyboyboo
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Just curious.
Thanks.
Thanks.
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I don't sit around the house and feel sorry for myself, there are better things to do.
Depression is about me!
Depression
It is important to appreciate that very few physicians would accept that depression is purely a biochemical phenomenon. Many other factors are thought to contribute; biological and genetic factors as well as personality traits and life events may all contribute. In addition, there are a number of psychological theories about the aetiology of depression. Perhaps the greatest areas of agreement about depression are that:
the condition is complex
there is no one explanation of its cause
there is no single treatment that will be effective in all cases.
What Happens in the Brain
The areas of the brain implicated in depression are the forebrain and the limbic system .
Many structures of the forebrain appear to be involved in depression, although it is not certain if a disturbance to these brain areas causes depression, or if they are simply affected in the course of the disease. The brain areas involved include the frontal and temporal lobes of the forebrain, the basal nuclei , and parts of the limbic system including the hippocampus , amygdala and the cingulate gyrus . The cerebral cortex controls thinking and it is likely that abnormalities in this part of the forebrain are responsible for the negative thoughts that are typical of depression.
The hypothalamus and the pituitary gland may also play a role in depression, as they are involved in hormonal control, and increased levels of some hormones may play a role in maintaining a depressed state.
If the body is placed under stress, the hypothalamus-pituitary-adrenal axis becomes activated. The hypothalamus produces corticotropin releasing factor (CRF) which is hypothesised to play a role in the precipitation of certain forms of depression. CRF stimulates the pituitary gland to secrete adrenocorticotropic hormone, which in turn stimulates the adrenal glands to release cortisol. Cortisol depresses mood and approximately 50% of people with severe depression have raised cortisol levels.
In the brainstem , the raphe nuclei and the locus coeruleus are involved in the transmission of signals to other parts of the brain, and are likely to be involved in depression. An imbalance or deficiency of the neurotransmitters , serotonin, noradrenaline and dopamine are implicated in depression, although it may be a change in receptor function, and not neurotransmitter concentration, that causes depression.
The best way to fight depression is count your blessings and pray for the needs of others. If you have a blessing in your life and you turn it into somthing good for someone else you will always have that blessing! The best blessing I can think of is seizure freedom for us all.