Why oh why did I have a seizure

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Stalwart
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I've been seizure free for two years until recently. I've been trying to figure out why. I can't come up with much of an answer, my sleeping pattern is odd.

I usually change my sleep schedule. It's like, for a week I will go to bed at 9pm, next week 11pm, then 3am, then it'll go on and on like that until I hit 8pm again which usually is roughly one month. Could that be one of the triggers for seizures?

I started reading up on aspartame. I always brushed it off as a conspiracy theory, even before I had epilepsy and after I brushed it off. I've been drinking a lot more coke zero (5 a day) recently. I read this: http://www.naturalnews.com/008952_aspartame_seizures.html

A 35-year-old male anesthetist had three grand mal seizures, severe headaches and visual difficulty while drinking 4-6 diet colas daily, but none for two years after stopping aspartame. He told the U. S. Senate hearing on "NutraSweet"—Health and Safety Concerns, held on November 3, 1987:
Aspartame - Is It Safe by H J Roberts MD, page 14

I went two years, until just now. I want to know why. I realize there were other triggers. When I get up early in the morning, my memory would clear for couple of seconds and I would feel my hand drop to the desk without actually doing it by intention. I've been going to sleep, and waking up to my leg jumping up.

Do you become immune to drugs after certain period of time?

Do any of you think my increased consumption of diet sodas with aspartame could be partly responsible? I should be asking my doctor this I realize it, but I can't ever talk to him directly. I always talk to his nurse, and she calls me back. I have to go visit him every 6 months to ask these questions. Anyway, would by sleeping pattern or diet sodas be increasing it? Thanks.

Starting today I am going to reduce my consumption of diet sodas to water and nothing else. I will see if that helps with me losing weight, etc.
 
Interrupted sleep and altered sleep patterns can be a trigger for me, an abundance of good quality sleep is critical for me.

Aspartame can be a trigger for some people who seem sensitive to it, it does not cause me any problems. Diet sodas are just a liquid laboratory experiment diluted with filtered water, best to avoid them.

Yes you can become immune to drugs as in they lose their effectiveness and require dosing increases or addition of a second drug or even a change to a different drug if it loses all effectiveness.
Changes in brand of medication, body weight, diet, illness, season, can all cause changes in how the body responds to our meds.

Sometimes trying to find a reason for a seizure is an exercise in futility, was it a single thing that triggered it? Was it the culmination of a bunch of little things? Or was it just that sometimes a brain prone to having seizures is going to seize?

For me I have to get lots of sleep including taking naps, eat a healthy(ish) diet, exercise, and try to change how I handle stress as much as possible.
 
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My very first seizures arrived out of the blue after a three-day stretch when I...
1. Hadn't been sleeping and 2. hadn't been consuming anything, except for 3. Diet soda (w. aspartame).

Both sleep issues and dietary issues can be triggering, especially if you already have a lowered seizure threshold. And yes, some people build up a tolerance to anti-seizure meds as well.

Fatigue is the #1 seizure trigger so the more you can proactive about getting good quality sleep, the better. Having consistent sleep times is easier on the brain and body. If you are taking your meds at consistent times, but constantly changing your sleep and activity levels significantly, then that can also potentially affect the metabolism rate of your meds, and in turn their efficacy.

As for sodas with aspartame, yes they can have a triggering effect for some people. Aspartame mimics aspartic acid, which is one of neurotransmitters that stimulates the brain (msg is another food additive that can have similar effects by mimicking glutamic acid, also a neurotransmitter that plays a role in stimulating the brain). Along with there are other potential problems with high diet-soda consumption:

1. Depleted magnesium. Magnesium plays a huge role in protecting the brain. High phosphoric acid levels in soda and/or high consumption of such sodas can lead to reduced magnesium and calcium in you body. The phosphorous binds with those minerals in your blood so that your body can't store them. It's important to make sure that you are getting plenty of other sources of maagnesium (as well as calcium and vitamin D) in your diet, and not consuming sodas at the same time. In addition, aspartame/aspartic acid interferes with magnesium as well, and chronic aspartame ingestion can potentially deplete magnesium.

2. Too much caffeine. Not only is its stimulant effect triggering for some, but caffeine ALSO can deplete the body of minerals including magnesium and calcium, especially if you aren't consuming a whole lot of other foods.

If you are drinking 5 sodas a day, your diet may (or may not) contain other imbalances that can be triggering if you have epilepsy, things like low-blood sugar, dehydration, electrolyte imbalance, and/or excessive consumption of foods with high glycemic index (carbs for the most part).

The above factors may or may not have led to your seizure breakthrough, but it's great that you are taking a closer look at dietary or sleep issues and are being proactive in making changes. It's good to go slow though -- going cold turkey on any substance (including caffeine) can be stressful on the brain.

Good luck!
Nak
 
The hospital did a electrolyte blood test. They said it can make seizures happen or get worse. They said mine was normal.
 
If I remember correctly a standard electrolyte test will not detect long term magnesium deficiency, it only test circulating electrolytes not what is stored.

There is some kind of blood cell/red blood cell test that measures the magnesium in the blood cells themselves.

I cannot remember what it is called and my Google fu is not working today.
 
Not getting enough sleep is a HUGE seizure trigger for me. I usually go to sleep around midnight and get up around 10 am. I'm pretty good at sticking to this schedule. I take an hour or two nap in the afternoon also. It seems if I go too many days without that nap I'm almost sure to have a seizure.

Caffeine is also a seizure trigger for me. I'm ok having a cup or two of coffee or soda a day every so often but when I drink a ton of I might have a seizure. If I drink caffeine in the evening I'll usually fall asleep later than normal too. This will cause me to not get enough sleep and that can bring on a seizure as I said.
 
I finally did my own thinking. I remember my doctor talking about how his patients were on brand name drugs then pharmacists prescribed generic versions, and his patents started having seizures.

I looked further into this, I found that the FDA has a rule that a generic version must be within 80 to 120% of bioequivalence. I assume this is still accurate. Okay, now I had my medication refilled on the 13th. I started taking that. Okay, I had a seizure on the 21st. Coincidence? I checked the brand it's teva. I have multiple bottles that I haven't thrown away, I checked, they're all the same brand.

Am I just being paranoid? I think it is the generic version of the drug. I don't just want to be told it's just a break through seizure, and it's just something that happens. I think there is a reason behind it. I think this is perhaps possible. I'm not sure, since it's the brand name teva though. Has anybody else had issues?
 
No you not paranoid it happens with lots of medication thyroxin that another and my brother inlaw put on the cheap insulin he had countless hypos now where the other stuff he was fine again a cost thing.
I was told medication made all over the world thus travels through countless weather atmospheric conditions and who knows how old the different ingredients are
 
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